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PDB: 435 件
5F67
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An exquisitely specific PDZ/target recognition revealed by the structure of INAD PDZ3 in complex with TRP channel tail
分子名称: Inactivation-no-after-potential D protein, TRP C terminal Tail
著者Ye, F, Shang, Y, Liu, W, Zhang, M.
登録日2015-12-05
公開日2016-02-24
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.76 Å)
主引用文献An Exquisitely Specific PDZ/Target Recognition Revealed by the Structure of INAD PDZ3 in Complex with TRP Channel Tail
Structure, 24, 2016
2IDG
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Crystal Structure of hypothetical protein AF0160 from Archaeoglobus fulgidus
分子名称: Hypothetical protein AF0160
著者Zhao, M, Zhang, M, Chang, J, Chen, L, Xu, H, Li, Y, Liu, Z.J, Rose, J.P, Wang, B.C, Southeast Collaboratory for Structural Genomics (SECSG)
登録日2006-09-15
公開日2006-11-14
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.69 Å)
主引用文献Crystal structure of Hypothetical Protein AF0160 from Archaeoglobus fulgidus at 2.69 Angstrom resolution
To be Published
8YUV
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Cryo-EM structure of the immepip-bound H3R-Gi complex
分子名称: 4-(1H-imidazol-5-ylmethyl)piperidine, CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
著者Shen, Q, Tang, X, Wen, X, Cheng, S, Xiao, P, Zang, S, Shen, D, Jiang, L, Zheng, Y, Zhang, H, Xu, H, Mao, C, Zhang, M, Hu, W, Sun, J, Chen, Z, Zhang, Y.
登録日2024-03-27
公開日2024-06-05
最終更新日2024-11-06
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Molecular Determinant Underlying Selective Coupling of Primary G-Protein by Class A GPCRs.
Adv Sci, 11, 2024
8YUU
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BU of 8yuu by Molmil
Cryo-EM structure of the histamine-bound H3R-Gi complex
分子名称: CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
著者Shen, Q, Tang, X, Wen, X, Cheng, S, Xiao, P, Zang, S, Shen, D, Jiang, L, Zheng, Y, Zhang, H, Xu, H, Mao, C, Zhang, M, Hu, W, Sun, J, Chen, Z, Zhang, Y.
登録日2024-03-27
公開日2024-06-05
最終更新日2024-10-30
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Molecular Determinant Underlying Selective Coupling of Primary G-Protein by Class A GPCRs.
Adv Sci, 11, 2024
8YUT
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Cryo-EM structure of the amthamine-bound H2R-Gs complex
分子名称: 5-(2-azanylethyl)-4-methyl-1,3-thiazol-2-amine, CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
著者Shen, Q, Tang, X, Wen, X, Cheng, S, Xiao, P, Zang, S, Shen, D, Jiang, L, Zheng, Y, Zhang, H, Xu, H, Mao, C, Zhang, M, Hu, W, Sun, J, Chen, Z, Zhang, Y.
登録日2024-03-27
公開日2024-06-05
最終更新日2024-11-20
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Molecular Determinant Underlying Selective Coupling of Primary G-Protein by Class A GPCRs.
Adv Sci, 11, 2024
7DJZ
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BU of 7djz by Molmil
Crystal structure of SARS-CoV-2 Spike RBD in complex with MW01 Fab
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CITRIC ACID, MW01 heavy chain, ...
著者Wang, J, Jiao, S, Wang, R, Zhang, J, Zhang, M, Wang, M.
登録日2020-11-22
公開日2021-06-09
最終更新日2024-11-20
実験手法X-RAY DIFFRACTION (2.397 Å)
主引用文献Antibody-dependent enhancement (ADE) of SARS-CoV-2 pseudoviral infection requires Fc gamma RIIB and virus-antibody complex with bivalent interaction.
Commun Biol, 5, 2022
7DK0
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BU of 7dk0 by Molmil
Crystal structure of SARS-CoV-2 Spike RBD in complex with MW05 Fab
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, MW05 heavy chain, MW05 light chain, ...
著者Wang, J, Jiao, S, Wang, R, Zhang, J, Zhang, M, Wang, M.
登録日2020-11-22
公開日2021-06-09
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (3.199 Å)
主引用文献Antibody-dependent enhancement (ADE) of SARS-CoV-2 pseudoviral infection requires Fc gamma RIIB and virus-antibody complex with bivalent interaction.
Commun Biol, 5, 2022
5ET0
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Crystal structure of Myo3b-ARB2 in complex with Espin1-AR
分子名称: Espin, Myosin-IIIb
著者Liu, H, Li, J, Liu, W, Zhang, M.
登録日2015-11-17
公開日2016-02-03
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Myosin III-mediated cross-linking and stimulation of actin bundling activity of Espin
Elife, 5, 2016
5ET1
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Crystal structure of Myo3b-ARB1 in complex with Espin1-AR
分子名称: Espin, GLYCEROL, Myosin-IIIb
著者Liu, H, Li, J, liu, W, Zhang, M.
登録日2015-11-17
公開日2016-02-03
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Myosin III-mediated cross-linking and stimulation of actin bundling activity of Espin
Elife, 5, 2016
4D8O
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Crystal Structure of the ankyrin-B ZU5-ZU5-UPA-DD tandem
分子名称: Ankyrin-2
著者Wei, Z, Wang, C, Yu, C, Zhang, M.
登録日2012-01-11
公開日2012-03-28
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.203 Å)
主引用文献Structure of the ZU5-ZU5-UPA-DD tandem of ankyrin-B reveals interaction surfaces necessary for ankyrin function
Proc.Natl.Acad.Sci.USA, 109, 2012
8WZZ
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BU of 8wzz by Molmil
Short-chain dehydrogenase/reductase16 (SDR16) from Antrodia camphorata
分子名称: SDR16
著者Zhang, Y.Q, Zhang, M, Ye, M.
登録日2023-11-02
公開日2024-11-06
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Short-chain dehydrogenase/reductase16 (SDR16) from Antrodia camphorata
To Be Published
4DC2
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BU of 4dc2 by Molmil
Structure of PKC in Complex with a Substrate Peptide from Par-3
分子名称: ADENINE, Partitioning defective 3 homolog, Protein kinase C iota type
著者Shang, Y, Wang, C, Yu, J, Zhang, M.
登録日2012-01-17
公開日2012-07-11
最終更新日2024-11-20
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Substrate recognition mechanism of atypical protein kinase Cs revealed by the structure of PKC iota in complex with a substrate peptide from Par-3
Structure, 20, 2012
8I3E
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BU of 8i3e by Molmil
Crystal structure of ELKS1 in complex with Piccolo
分子名称: ELKS/Rab6-interacting/CAST family member 1, MKIAA0559 protein
著者Cai, Q, Zhang, M.
登録日2023-01-17
公開日2024-01-24
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Short-distance vesicle transport via phase separation.
Cell, 187, 2024
4EGX
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BU of 4egx by Molmil
Crystal structure of KIF1A CC1-FHA tandem
分子名称: DI(HYDROXYETHYL)ETHER, GLYCEROL, Kinesin-like protein KIF1A
著者Yu, J, Huo, L, Yue, Y, Xu, T, Zhang, M, Feng, W.
登録日2012-04-02
公開日2012-10-03
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.51 Å)
主引用文献The CC1-FHA Tandem as a Central Hub for Controlling the Dimerization and Activation of Kinesin-3 KIF1A
Structure, 20, 2012
8XVN
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BU of 8xvn by Molmil
Short-chain dehydrogenase/reductase6 (SDR6) from Antrodia camphorata
分子名称: Short-chain dehydrogenases/reductase
著者Zhang, Y.Q, Zhang, M, Ye, M.
登録日2024-01-15
公開日2025-01-15
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Short-chain dehydrogenase/reductase6 (SDR6) from Antrodia camphorata
To Be Published
8XVO
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BU of 8xvo by Molmil
Crystal structure of a short-chain dehydrogenase/reductase 16 (SDR16) from Antrodia camphorata
分子名称: GLYCEROL, short-chain dehydrogenase/reductase 16
著者Zhang, Y.Q, Zhang, M, Ye, M.
登録日2024-01-15
公開日2025-01-15
実験手法X-RAY DIFFRACTION (1.946 Å)
主引用文献Crystal structure of a short-chain dehydrogenase/reductase 16 (SDR16) from Antrodia camphorata
To Be Published
4EJQ
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BU of 4ejq by Molmil
Crystal structure of KIF1A C-CC1-FHA
分子名称: Kinesin-like protein KIF1A
著者Huo, L, Yue, Y, Ren, J, Yu, J, Liu, J, Yu, Y, Ye, F, Xu, T, Zhang, M, Feng, W.
登録日2012-04-06
公開日2012-10-03
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.893 Å)
主引用文献The CC1-FHA Tandem as a Central Hub for Controlling the Dimerization and Activation of Kinesin-3 KIF1A
Structure, 20, 2012
4EDJ
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Crystal structure of the GRASP55 GRASP Domain with a phosphomimetic mutation (S189D)
分子名称: Golgi reassembly-stacking protein 2, POTASSIUM ION
著者Truschel, S.T, Zhang, M, Bachert, C, Macbeth, M.R, Linstedt, A.D.
登録日2012-03-27
公開日2012-05-09
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.901 Å)
主引用文献Allosteric Regulation of GRASP Protein-dependent Golgi Membrane Tethering by Mitotic Phosphorylation.
J.Biol.Chem., 287, 2012
7DPM
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BU of 7dpm by Molmil
Crystal structure of SARS-CoV-2 Spike RBD in complex with MW06 Fab
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1, ...
著者Wang, J, Jiao, S, Wang, R, Zhang, J, Zhang, M, Wang, M.
登録日2020-12-20
公開日2021-02-17
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (3.304 Å)
主引用文献Characterization of MW06, a human monoclonal antibody with cross-neutralization activity against both SARS-CoV-2 and SARS-CoV.
Mabs, 13, 2021
2NS5
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BU of 2ns5 by Molmil
The conserved N-terminal domain of Par-3 adopts a novel PB1-like structure required for Par-3 oligomerization and apical membrane localization
分子名称: Partitioning-defective 3 homolog
著者Feng, W, Wu, H, Chan, L.-N, Zhang, M.
登録日2006-11-03
公開日2007-09-04
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献The Par-3 NTD adopts a PB1-like structure required for Par-3 oligomerization and membrane localization
Embo J., 26, 2007
7X1N
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Crystal structure of MEF2D-MRE complex
分子名称: DNA (5'-D(P*AP*AP*CP*TP*AP*TP*TP*TP*AP*TP*AP*AP*G)-3'), DNA (5'-D(P*TP*CP*TP*TP*AP*TP*AP*AP*AP*TP*AP*GP*T)-3'), Myocyte enhancer factor 2D/deleted in azoospermia associated protein 1 fusion protein
著者Zhang, H, Zhang, M, Wang, Q.Q, Chen, Z, Chen, S.J, Meng, G.
登録日2022-02-24
公開日2022-05-25
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.315 Å)
主引用文献Functional, structural, and molecular characterizations of the leukemogenic driver MEF2D-HNRNPUL1 fusion.
Blood, 140, 2022
6ZH0
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Structure of human galactokinase 1 bound with 2-(4-chlorophenyl)-N-(pyrimidin-2-yl)acetamide
分子名称: 2-(1,3-benzoxazol-2-ylamino)spiro[1,6,7,8-tetrahydroquinazoline-4,1'-cyclohexane]-5-one, Galactokinase, N-(3-chlorophenyl)-2,2,2-trifluoroacetamide, ...
著者Mackinnon, S.R, Bezerra, G.A, Zhang, M, Foster, W, Krojer, T, Brandao-Neto, J, Douangamath, A, Arrowsmith, C, Edwards, A, Bountra, C, Brennan, P, Lai, K, Yue, W.W.
登録日2020-06-20
公開日2022-06-01
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Fragment Screening Reveals Starting Points for Rational Design of Galactokinase 1 Inhibitors to Treat Classic Galactosemia.
Acs Chem.Biol., 16, 2021
7XJF
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Crystal structure of 6MW3211 Fab in complex with CD47
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ...
著者Wang, J, Wang, R, Jiao, S, Wang, S, Zhang, J, Zhang, M, Wang, M.
登録日2022-04-16
公開日2023-05-31
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Blockade of dual immune checkpoint inhibitory signals with a CD47/PD-L1 bispecific antibody for cancer treatment.
Theranostics, 13, 2023
2OGP
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Solution structure of the second PDZ domain of Par-3
分子名称: Partitioning-defective 3 homolog
著者Feng, W, Wu, H, Chen, J, Chan, L.-N, Zhang, M.
登録日2007-01-07
公開日2007-12-25
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献PDZ domains of par-3 as potential phosphoinositide signaling integrators
Mol.Cell, 28, 2007
2FJL
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Solution Structure of the Split PH domain in Phospholipase C-gamma1
分子名称: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1
著者Wen, W, Zhang, M.
登録日2006-01-03
公開日2006-03-14
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Structural Characterization of the Split Pleckstrin Homology Domain in Phospholipase C-{gamma}1 and Its Interaction with TRPC3
J.Biol.Chem., 281, 2006

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件を2025-04-16に公開中

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