3U3T
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![BU of 3u3t by Molmil](/molmil-images/mine/3u3t) | The S-SAD phased crystal structure of the ecto-domain of Death Receptor 6 (DR6) | Descriptor: | Tumor necrosis factor receptor superfamily member 21 | Authors: | Ru, H, Zhao, L.X, Ding, W, Jiao, L.Y, Shaw, N, Zhang, L.G, Hung, L.W, Matsugaki, N, Wakatsuki, S, Liu, Z.J. | Deposit date: | 2011-10-06 | Release date: | 2012-05-02 | Last modified: | 2012-07-11 | Method: | X-RAY DIFFRACTION (3.21 Å) | Cite: | S-SAD phasing study of death receptor 6 and its solution conformation revealed by SAXS Acta Crystallogr.,Sect.D, 68, 2012
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5DP3
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![BU of 5dp3 by Molmil](/molmil-images/mine/5dp3) | Crystal Structure of EV71 3C Proteinase in complex with compound 2 | Descriptor: | 3C proteinase, ethyl (4S)-5-[(3S)-2-oxopyrrolidin-3-yl]-4-[(3-phenylpropanoyl)amino]pent-2-enoate | Authors: | Wu, C, Zhang, L, Li, P, Cai, Q, Peng, X, Li, N, Cai, Y, Li, J, Lin, T. | Deposit date: | 2015-09-12 | Release date: | 2016-03-30 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Fragment-wise design of inhibitors to 3C proteinase from enterovirus 71 Biochim.Biophys.Acta, 1860, 2016
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7X2M
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![BU of 7x2m by Molmil](/molmil-images/mine/7x2m) | Crystal structure of nanobody 1-2C7 with SARS-CoV-2 RBD | Descriptor: | 1-2C7, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-D-mannopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1 | Authors: | Wang, X.Q, Zhang, L.Q, Ren, Y.F, Li, M.X. | Deposit date: | 2022-02-25 | Release date: | 2022-12-14 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Broadly neutralizing and protective nanobodies against SARS-CoV-2 Omicron subvariants BA.1, BA.2, and BA.4/5 and diverse sarbecoviruses. Nat Commun, 13, 2022
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7X2J
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![BU of 7x2j by Molmil](/molmil-images/mine/7x2j) | Crystal structure of nanobody Nb70 with SARS-CoV RBD | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Nb70, Spike protein S1 | Authors: | Wang, X.Q, Zhang, L.Q, Ren, Y.F, Li, M.X. | Deposit date: | 2022-02-25 | Release date: | 2022-12-21 | Last modified: | 2023-06-28 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Broadly neutralizing and protective nanobodies against SARS-CoV-2 Omicron subvariants BA.1, BA.2, and BA.4/5 and diverse sarbecoviruses. Nat Commun, 13, 2022
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5UP8
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![BU of 5up8 by Molmil](/molmil-images/mine/5up8) | Crystal Structure of the Zn-bound Human Heavy-Chain variant 122H-delta C-star with para-benzenedihydroxamate | Descriptor: | Ferritin heavy chain, N,N'-dihydroxybenzene-1,4-dicarboxamide, SODIUM ION, ... | Authors: | Bailey, J.B, Zhang, L, Chiong, J.C, Ahn, S, Tezcan, F.A. | Deposit date: | 2017-02-01 | Release date: | 2017-06-21 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.631 Å) | Cite: | Synthetic Modularity of Protein-Metal-Organic Frameworks. J. Am. Chem. Soc., 139, 2017
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7C81
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![BU of 7c81 by Molmil](/molmil-images/mine/7c81) | E30 F-particle in complex with 6C5 | Descriptor: | Heavy chain, Light chain, SPHINGOSINE, ... | Authors: | Wang, K, Zheng, B, Zhang, L, Cui, L, Su, X, Zhang, Q, Guo, Y, Zhu, L, Zhu, F, Rao, Z, Wang, X. | Deposit date: | 2020-05-28 | Release date: | 2020-07-29 | Last modified: | 2020-09-16 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Serotype specific epitopes identified by neutralizing antibodies underpin immunogenic differences in Enterovirus B. Nat Commun, 11, 2020
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7CFM
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![BU of 7cfm by Molmil](/molmil-images/mine/7cfm) | Cryo-EM structure of the P395-bound GPBAR-Gs complex | Descriptor: | 2-(ethylamino)-6-[3-(4-propan-2-ylphenyl)propanoyl]-7,8-dihydro-5H-pyrido[4,3-d]pyrimidine-4-carboxamide, CHOLESTEROL, G-protein coupled bile acid receptor 1, ... | Authors: | Yang, F, Mao, C, Guo, L, Lin, J, Ming, Q, Xiao, P, Wu, X, Shen, Q, Guo, S, Shen, D, Lu, R, Zhang, L, Huang, S, Ping, Y, Zhang, C, Ma, C, Zhang, K, Liang, X, Shen, Y, Nan, F, Yi, F, Luca, V, Zhou, J, Jiang, C, Sun, J, Xie, X, Yu, X, Zhang, Y. | Deposit date: | 2020-06-27 | Release date: | 2020-09-09 | Last modified: | 2020-12-02 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Structural basis of GPBAR activation and bile acid recognition. Nature, 587, 2020
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8J8J
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![BU of 8j8j by Molmil](/molmil-images/mine/8j8j) | Membrane bound PRTase, C3 symmetry, donor bound | Descriptor: | (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, Decaprenyl-phosphate phosphoribosyltransferase, ... | Authors: | Wu, F.Y, Gao, S, Zhang, L, Rao, Z.H. | Deposit date: | 2023-05-01 | Release date: | 2024-02-07 | Last modified: | 2024-04-17 | Method: | ELECTRON MICROSCOPY (2.76 Å) | Cite: | Structural analysis of phosphoribosyltransferase-mediated cell wall precursor synthesis in Mycobacterium tuberculosis. Nat Microbiol, 9, 2024
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8CTJ
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![BU of 8ctj by Molmil](/molmil-images/mine/8ctj) | Cryo-EM structure of TMEM87A | Descriptor: | 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, Transmembrane protein 87A | Authors: | Hoel, C.M, Zhang, L, Brohawn, S.G. | Deposit date: | 2022-05-15 | Release date: | 2022-07-20 | Last modified: | 2022-11-30 | Method: | ELECTRON MICROSCOPY (4.74 Å) | Cite: | Structure of the GOLD-domain seven-transmembrane helix protein family member TMEM87A. Elife, 11, 2022
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7CFN
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![BU of 7cfn by Molmil](/molmil-images/mine/7cfn) | Cryo-EM structure of the INT-777-bound GPBAR-Gs complex | Descriptor: | (2S,4R)-4-[(3R,5S,6R,7R,8R,9S,10S,12S,13R,14S,17R)-6-ethyl-10,13-dimethyl-3,7,12-tris(oxidanyl)-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-methyl-pentanoic acid, CHOLESTEROL, G-protein coupled bile acid receptor 1, ... | Authors: | Yang, F, Mao, C, Guo, L, Lin, J, Ming, Q, Xiao, P, Wu, X, Shen, Q, Guo, S, Shen, D, Lu, R, Zhang, L, Huang, S, Ping, Y, Zhang, C, Ma, C, Zhang, K, Liang, X, Shen, Y, Nan, F, Yi, F, Luca, V, Zhou, J, Jiang, C, Sun, J, Xie, X, Yu, X, Zhang, Y. | Deposit date: | 2020-06-27 | Release date: | 2020-09-09 | Last modified: | 2021-04-07 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Structural basis of GPBAR activation and bile acid recognition. Nature, 587, 2020
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7C80
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![BU of 7c80 by Molmil](/molmil-images/mine/7c80) | E30 F-particle in complex with 4B10 | Descriptor: | Heavy chain, Light chain, SPHINGOSINE, ... | Authors: | Wang, K, Zheng, B, Zhang, L, Cui, L, Su, X, Zhang, Q, Guo, Y, Zhu, L, Zhu, F, Rao, Z, Wang, X. | Deposit date: | 2020-05-28 | Release date: | 2020-07-29 | Last modified: | 2020-09-16 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Serotype specific epitopes identified by neutralizing antibodies underpin immunogenic differences in Enterovirus B. Nat Commun, 11, 2020
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2K8P
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![BU of 2k8p by Molmil](/molmil-images/mine/2k8p) | Characterisation of the structural features and interactions of sclerostin: molecular insight into a key regulator of Wnt-mediated bone formation | Descriptor: | Sclerostin | Authors: | Veverka, V, Henry, A.J, Slocombe, P.M, Ventom, A, Mulloy, B, Muskett, F.W, Muzylak, M, Greenslade, K, Moore, A, Zhang, L, Gong, J, Qian, X, Paszty, C, Taylor, R.J, Robinson, M.K, Carr, M.D. | Deposit date: | 2008-09-18 | Release date: | 2009-02-17 | Last modified: | 2022-03-16 | Method: | SOLUTION NMR | Cite: | Characterization of the Structural Features and Interactions of Sclerostin: Molecular insight into a key regulator of Wnt-mediated bone formation J.Biol.Chem., 284, 2009
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8JI8
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![BU of 8ji8 by Molmil](/molmil-images/mine/8ji8) | Crystal Structure of Prophenoloxidase PPO6 chimeric mutant (F215EASNRAIVD224 to G215DGPDSVVR223) from Aedes aegypti | Descriptor: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, COPPER (II) ION, ... | Authors: | Zhu, X, Zhang, L, Yang, X, Bao, P, Ren, D, Han, Q. | Deposit date: | 2023-05-26 | Release date: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | Mosquitoes have evolved two types of prophenoloxidases To Be Published
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8JIB
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![BU of 8jib by Molmil](/molmil-images/mine/8jib) | Crystal Structure of Prophenoloxidase PPO6 from Aedes aegypti | Descriptor: | 1,2-ETHANEDIOL, COPPER (II) ION, TK receptor | Authors: | Zhu, X, Zhang, L, Yang, X, Bao, P, Ren, D, Han, Q. | Deposit date: | 2023-05-26 | Release date: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3.15 Å) | Cite: | Mosquitoes have evolved two types of prophenoloxidases To Be Published
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7E8M
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![BU of 7e8m by Molmil](/molmil-images/mine/7e8m) | Crystal structure of SARS-CoV-2 antibody P2C-1F11 with mutated RBD | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1, antibody P2C-1F11 heavy chain, ... | Authors: | Wang, X.Q, Zhang, L.Q, Ge, J.W, Wang, R.K, Lan, J. | Deposit date: | 2021-03-02 | Release date: | 2021-05-26 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.09 Å) | Cite: | Analysis of SARS-CoV-2 variant mutations reveals neutralization escape mechanisms and the ability to use ACE2 receptors from additional species. Immunity, 54, 2021
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7EBX
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![BU of 7ebx by Molmil](/molmil-images/mine/7ebx) | Crystal structure of juvenile hormone acid methyltransferase JHAMT in complex with S-adenosyl-L-homocysteine. | Descriptor: | S-ADENOSYL-L-HOMOCYSTEINE, juvenile hormone acid methyltransferase | Authors: | Guo, P.C, Zhang, Y.S, Zhang, L, Xu, H.Y, Xia, Q.Y. | Deposit date: | 2021-03-11 | Release date: | 2021-09-29 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.89 Å) | Cite: | Structural basis for juvenile hormone biosynthesis by the juvenile hormone acid methyltransferase. J.Biol.Chem., 297, 2021
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7EC0
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![BU of 7ec0 by Molmil](/molmil-images/mine/7ec0) | Crystal structure of juvenile hormone acid methyltransferase JHAMT in complex with S-Adenosyl homocysteine and methyl farnesoate | Descriptor: | Juvenile hormone acid methyltransferase, Methyl farnesoate, S-ADENOSYL-L-HOMOCYSTEINE | Authors: | Guo, P.C, Zhang, Y.S, Zhang, L, Xu, H.Y, Xia, Q.Y. | Deposit date: | 2021-03-11 | Release date: | 2021-09-29 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.494 Å) | Cite: | Structural basis for juvenile hormone biosynthesis by the juvenile hormone acid methyltransferase. J.Biol.Chem., 297, 2021
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8JTL
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![BU of 8jtl by Molmil](/molmil-images/mine/8jtl) | Structure of OY phytoplasma SAP05 binding with AtRpn10 | Descriptor: | 26S proteasome non-ATPase regulatory subunit 4 homolog, Sequence-variable mosaic (SVM) signal sequence domain-containing protein | Authors: | Du, Y.X, Zhang, L.Y, Zheng, Q.Y. | Deposit date: | 2023-06-22 | Release date: | 2023-07-12 | Last modified: | 2024-07-17 | Method: | X-RAY DIFFRACTION (1.78 Å) | Cite: | Structure basis for recognition of plant Rpn10 by phytoplasma SAP05 in ubiquitin-independent protein degradation. Iscience, 27, 2024
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8JTK
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![BU of 8jtk by Molmil](/molmil-images/mine/8jtk) | Structure of AYWB phytoplasma SAP05 recognizing AtRpn10 | Descriptor: | 26S proteasome non-ATPase regulatory subunit 4 homolog, Sequence-variable mosaic (SVM) signal sequence domain-containing protein | Authors: | Du, Y.X, Zhang, L.Y, Zheng, Q.Y. | Deposit date: | 2023-06-22 | Release date: | 2023-07-19 | Last modified: | 2024-07-17 | Method: | X-RAY DIFFRACTION (1.57 Å) | Cite: | Structure basis for recognition of plant Rpn10 by phytoplasma SAP05 in ubiquitin-independent protein degradation. Iscience, 27, 2024
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8JTR
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![BU of 8jtr by Molmil](/molmil-images/mine/8jtr) | Cryo-EM structure of GeoCas9-sgRNA binary complex | Descriptor: | CRISPR-associated endonuclease Cas9, sgRNA (139-bp) | Authors: | Shen, P.P, Liu, B.B, Li, X, Zhang, L.L, Chen, C.-C, Guo, R.-T. | Deposit date: | 2023-06-22 | Release date: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (3.21 Å) | Cite: | Cryo-EM structure of GeoCas9-sgRNA binary complex To Be Published
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8JTJ
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![BU of 8jtj by Molmil](/molmil-images/mine/8jtj) | Cryo-EM structure of GeoCas9-sgRNA-dsDNA ternary complex | Descriptor: | CRISPR-associated endonuclease Cas9, DNA (29-MER), DNA (5'-D(P*GP*GP*GP*CP*GP*CP*GP*AP*A)-3'), ... | Authors: | Shen, P.P, Liu, B.B, Li, X, Zhang, L.L, Chen, C.-C, Guo, R.-T. | Deposit date: | 2023-06-21 | Release date: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (3.08 Å) | Cite: | Cryo-EM structure of GeoCas9-sgRNA-DNA ternary complex To Be Published
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8H7P
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![BU of 8h7p by Molmil](/molmil-images/mine/8h7p) | Crystal structure of aqualigase bound with Suc-AAPF | Descriptor: | 5,6-DIHYDRO-BENZO[H]CINNOLIN-3-YLAMINE, CALCIUM ION, Subtilisin, ... | Authors: | Li, H, Ma, M.Z, Zhang, L.J, Dai, L, Chen, C.-C, Guo, R.-T. | Deposit date: | 2022-10-20 | Release date: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.82 Å) | Cite: | Crystal structure of aqualigase bound with Suc-AAPF To Be Published
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8H7O
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![BU of 8h7o by Molmil](/molmil-images/mine/8h7o) | Crystal structure of aqualigase | Descriptor: | CALCIUM ION, ISOPROPYL ALCOHOL, Subtilisin | Authors: | Li, H, Ma, M.Z, Zhang, L.J, Dai, L, Chen, C.-C, Guo, R.-T. | Deposit date: | 2022-10-20 | Release date: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Crystal structure of aqualigase To Be Published
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3VPM
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![BU of 3vpm by Molmil](/molmil-images/mine/3vpm) | Crystal structure of human ribonucleotide reductase subunit M2 (hRRM2) mutant | Descriptor: | FE (III) ION, MAGNESIUM ION, Ribonucleoside-diphosphate reductase subunit M2 | Authors: | Chen, X, Xu, Z, Liu, H, Zhang, L, Chen, B, Zhu, L, Yang, C, Zhu, W, Shao, J. | Deposit date: | 2012-03-05 | Release date: | 2013-03-06 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Essential role of E106 in the proton-coupled electron transfer in human ribonucleotide reductase M2 subunit To be Published
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7WUQ
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![BU of 7wuq by Molmil](/molmil-images/mine/7wuq) | Tethered peptide activation mechanism of adhesion GPCRs ADGRG2 and ADGRG4 | Descriptor: | Adhesion G-protein coupled receptor G2,mCherry, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | He, Q.T, Guo, S.C, Xiao, P, Sun, J.P, Yu, X, Gou, L, Kong, L.L, Zhang, L. | Deposit date: | 2022-02-09 | Release date: | 2022-04-27 | Last modified: | 2022-05-11 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Tethered peptide activation mechanism of the adhesion GPCRs ADGRG2 and ADGRG4. Nature, 604, 2022
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