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7E8M

Crystal structure of SARS-CoV-2 antibody P2C-1F11 with mutated RBD

Summary for 7E8M
Entry DOI10.2210/pdb7e8m/pdb
DescriptorSpike protein S1, antibody P2C-1F11 heavy chain, antibody P2C-1F11 light chain, ... (5 entities in total)
Functional Keywordssars-cov-2 spike, receptor binding domain, antibody, viral protein, viral protein-immune system complex, viral protein/immune system
Biological sourceSevere acute respiratory syndrome coronavirus 2 (2019-nCoV, SARS-CoV-2)
More
Total number of polymer chains3
Total formula weight68255.12
Authors
Wang, X.Q.,Zhang, L.Q.,Ge, J.W.,Wang, R.K.,Lan, J. (deposition date: 2021-03-02, release date: 2021-05-26, Last modification date: 2023-11-29)
Primary citationWang, R.,Zhang, Q.,Ge, J.,Ren, W.,Zhang, R.,Lan, J.,Ju, B.,Su, B.,Yu, F.,Chen, P.,Liao, H.,Feng, Y.,Li, X.,Shi, X.,Zhang, Z.,Zhang, F.,Ding, Q.,Zhang, T.,Wang, X.,Zhang, L.
Analysis of SARS-CoV-2 variant mutations reveals neutralization escape mechanisms and the ability to use ACE2 receptors from additional species.
Immunity, 54:1611-1621.e5, 2021
Cited by
PubMed: 34166623
DOI: 10.1016/j.immuni.2021.06.003
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.09 Å)
Structure validation

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