7E8M
Crystal structure of SARS-CoV-2 antibody P2C-1F11 with mutated RBD
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (E) | Spike protein S1 | polymer | 195 | 21907.6 | 1 | UniProt (P0DTC2) Pfam (PF09408) | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV SARS-CoV-2) | |
| 2 | B (H) | antibody P2C-1F11 heavy chain | polymer | 217 | 22851.6 | 1 | Homo sapiens | ||
| 3 | C (L) | antibody P2C-1F11 light chain | polymer | 214 | 23274.8 | 1 | Homo sapiens | ||
| 4 | D (E) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
| 5 | E, F, G (E, H, L) | water | water | 18.0 | 499 | Chemie (HOH) |
Sequence modifications
E: 333 - 527 (UniProt: P0DTC2)
| PDB | External Database | Details |
|---|---|---|
| Asn 417 | Lys 417 | engineered mutation |
| Lys 484 | Glu 484 | engineered mutation |
| Tyr 501 | Asn 501 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 68033.9 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 221.2 | |
| All* | Total formula weight | 68255.1 |
