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PDB: 784 件

3BN3
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crystal structure of ICAM-5 in complex with aL I domain
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ...
著者Zhang, H, Springer, T.A, Wang, J.-h.
登録日2007-12-13
公開日2008-08-19
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.099 Å)
主引用文献An unusual allosteric mobility of the C-terminal helix of a high-affinity alpha L integrin I domain variant bound to ICAM-5
Mol.Cell, 31, 2008
8HWQ
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Cryo-EM structure of human pannexin 3 with C-terminal truncated
分子名称: Pannexin-3
著者Zhang, H, Zhang, H, Wang, D.
登録日2023-01-02
公開日2024-01-17
実験手法ELECTRON MICROSCOPY (3.58 Å)
主引用文献Cryo-EM structure of human pannexin 3 with C-terminal truncated
To Be Published
1C1J
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BU of 1c1j by Molmil
STRUCTURE OF CADMIUM-SUBSTITUTED PHOSPHOLIPASE A2 FROM AGKISTRONDON HALYS PALLAS AT 2.8 ANGSTROMS RESOLUTION
分子名称: BASIC PHOSPHOLIPASE A2, CADMIUM ION, octyl beta-D-glucopyranoside
著者Zhang, H.-l, Zhang, Y.-q, Song, S.-y, Zhou, Y, Lin, Z.-j.
登録日1999-07-22
公開日2002-07-05
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure of Cadmium-substituted Phospholipase A2 from Agkistrodon halys Pallas at 2.8 Angstroms Resolution
Protein Pept.Lett., 6, 1999
5F1O
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BU of 5f1o by Molmil
human CD38 in complex with nanobody MU551
分子名称: ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1, nanobody MU551
著者Zhang, H, Hao, Q.
登録日2015-11-30
公開日2016-06-15
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Immuno-targeting the multifunctional CD38 using nanobody
Sci Rep, 6, 2016
5GRM
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BU of 5grm by Molmil
Crystal structure of rat STING in complex with cyclic GMP-AMP with 2'5'and 3'5'phosphodiester linkage(2'3'-cGAMP)
分子名称: Stimulator of interferon genes protein, cGAMP
著者Zhang, H, Han, M.J, Tao, J.L, Ye, Z.Y, Du, X.X, Deng, M.J, Zhang, X.Y, Li, L.F, Jiang, Z.F, Su, X.D.
登録日2016-08-11
公開日2017-10-25
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Crystal structure of rat STING in complex with cyclic GMP-AMP with 2'5'and 3'5'phosphodiester linkage(2'3'-cGAMP)
To Be Published
4E8B
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BU of 4e8b by Molmil
Crystal structure of 16S rRNA Methyltransferase RsmE from E.coli
分子名称: Ribosomal RNA small subunit methyltransferase E
著者Zhang, H, Gao, Z.Q, Dong, Y.H.
登録日2012-03-20
公開日2012-09-12
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.249 Å)
主引用文献Insights into the catalytic mechanism of 16S rRNA methyltransferase RsmE (m(3)U1498) from crystal and solution structures
J.Mol.Biol., 423, 2012
3ROP
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BU of 3rop by Molmil
Crystal structure of human CD38 in complex with compound CZ-50b
分子名称: 2-deoxy-2-fluoro-5-O-phosphono-alpha-D-ribofuranose, ADP-ribosyl cyclase 1, NICOTINAMIDE
著者Zhang, H, Lee, H.C, Hao, Q.
登録日2011-04-26
公開日2011-12-28
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献Catalysis-based inhibitors of the calcium signaling function of CD38.
Biochemistry, 51, 2012
8ITE
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BU of 8ite by Molmil
Crystal structure of pE301R from African swine fever virus
分子名称: Uncharacterized protein E301R
著者Zhang, H, Li, Y.H.
登録日2023-03-22
公開日2023-09-13
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The E301R protein of African swine fever virus functions as a sliding clamp involved in viral genome replication.
Mbio, 14, 2023
5XEZ
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Structure of the Full-length glucagon class B G protein-coupled receptor
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4-{[(4-cyclohexylphenyl){[3-(methylsulfonyl)phenyl]carbamoyl}amino]methyl}-N-(1H-tetrazol-5-yl)benzamide, ...
著者Zhang, H, Qiao, A, Yang, D, Yang, L, Dai, A, de Graaf, C, Reedtz-Runge, S, Dharmarajan, V, Zhang, H, Han, G.W, Grant, T, Sierra, R, Weierstall, U, Nelson, G, Liu, W, Wu, Y, Ma, L, Cai, X, Lin, G, Wu, X, Geng, Z, Dong, Y, Song, G, Griffin, P, Lau, J, Cherezov, V, Yang, H, Hanson, M, Stevens, R, Jiang, H, Wang, M, Zhao, Q, Wu, B.
登録日2017-04-06
公開日2017-05-24
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structure of the full-length glucagon class B G-protein-coupled receptor.
Nature, 546, 2017
5WUU
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Complex structure of the first bromodomain of BRD4 with an inhibitor that containing a 2H-chromen-2-one ring
分子名称: Bromodomain-containing protein 4, ~{N}-methyl-~{N}-[3-[(2-oxidanylidenechromen-4-yl)amino]propyl]thiophene-2-carboxamide
著者Zhang, H, Sun, Z.Y.
登録日2016-12-21
公開日2017-04-12
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.724 Å)
主引用文献Discovery of novel BRD4 inhibitors by high-throughput screening, crystallography, and cell-based assays.
Bioorg. Med. Chem. Lett., 27, 2017
4E0Q
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BU of 4e0q by Molmil
Crystal structure of MPN domain from COP9 signalosome
分子名称: COP9 signalosome complex subunit 6
著者Zhang, H, Gao, Z.Q, Dong, Y.H.
登録日2012-03-05
公開日2012-03-21
最終更新日2012-11-21
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献The crystal structure of the MPN domain from the COP9 signalosome subunit CSN6
Febs Lett., 586, 2012
3ROQ
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BU of 3roq by Molmil
Crystal structure of human CD38 in complex with compound CZ-46
分子名称: (2R,3R,4S,5S)-4-fluoro-3,5-dihydroxytetrahydrofuran-2-yl 2-phenylethyl hydrogen (S)-phosphate, ADP-ribosyl cyclase 1
著者Zhang, H, Lee, H.C, Hao, Q.
登録日2011-04-26
公開日2011-12-21
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Catalysis-based inhibitors of the calcium signaling function of CD38.
Biochemistry, 51, 2012
3ROM
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BU of 3rom by Molmil
Crystal structure of human CD38 in complex with compound CZ-48
分子名称: 2-deoxy-2-fluoro-5-O-thiophosphono-alpha-D-arabinofuranose, ADP-ribosyl cyclase 1
著者Zhang, H, Lee, H.C, Hao, Q.
登録日2011-04-26
公開日2011-12-21
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.04 Å)
主引用文献Catalysis-based inhibitors of the calcium signaling function of CD38.
Biochemistry, 51, 2012
5YQZ
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BU of 5yqz by Molmil
Structure of the glucagon receptor in complex with a glucagon analogue
分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glucagon analogue, ...
著者Zhang, H, Qiao, A, Yang, L, VAN EPS, N, Frederiksen, K, Yang, D, Dai, A, Cai, X, Zhang, H, Yi, C, Can, C, He, L, Yang, H, Lau, J, Ernst, O, Hanson, M, Stevens, R, Wang, M, Seedtz-Runge, S, Jiang, H, Zhao, Q, Wu, B.
登録日2017-11-08
公開日2018-01-17
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structure of the glucagon receptor in complex with a glucagon analogue.
Nature, 553, 2018
3ROK
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BU of 3rok by Molmil
Crystal structure of human CD38 in complex with compound CZ-27
分子名称: 5-O-[(S)-butoxy(hydroxy)phosphoryl]-2-deoxy-2-fluoro-alpha-D-arabinofuranose, ADP-ribosyl cyclase 1
著者Zhang, H, Lee, H.C, Hao, Q.
登録日2011-04-26
公開日2011-12-21
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Catalysis-based inhibitors of the calcium signaling function of CD38.
Biochemistry, 51, 2012
4DCM
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BU of 4dcm by Molmil
Crystal Structure of methyltransferase RlmG modifying G1835 of 23S rRNA in Escherichia coli
分子名称: DI(HYDROXYETHYL)ETHER, Ribosomal RNA large subunit methyltransferase G, S-ADENOSYLMETHIONINE
著者Zhang, H, Gao, Z.Q, Dong, Y.H.
登録日2012-01-17
公開日2012-08-01
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (2.297 Å)
主引用文献Structural insights into the function of 23S rRNA methyltransferase RlmG (m2G1835) from Escherichia coli.
Rna, 18, 2012
6JYJ
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BU of 6jyj by Molmil
Crystal structure of FAM46B (TENT5B)
分子名称: CITRATE ANION, Terminal nucleotidyltransferase 5B
著者Zhang, H, Hu, J.L, Gao, S.
登録日2019-04-26
公開日2020-03-04
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.693199 Å)
主引用文献FAM46B is a prokaryotic-like cytoplasmic poly(A) polymerase essential in human embryonic stem cells.
Nucleic Acids Res., 48, 2020
3PCU
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BU of 3pcu by Molmil
Crystal structure of human retinoic X receptor alpha ligand-binding domain complexed with LX0278 and SRC1 peptide
分子名称: 2-[(2S)-6-(2-methylbut-3-en-2-yl)-7-oxo-2,3-dihydro-7H-furo[3,2-g]chromen-2-yl]propan-2-yl acetate, Nuclear receptor coactivator 2, Retinoic acid receptor RXR-alpha
著者Zhang, H, Zhang, Y, Shen, H, Chen, J, Li, C, Chen, L, Hu, L, Jiang, H, Shen, X.
登録日2010-10-22
公開日2011-11-16
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献(+)-Rutamarin as a Dual Inducer of Both GLUT4 Translocation and Expression Efficiently Ameliorates Glucose Homeostasis in Insulin-Resistant Mice.
Plos One, 7, 2012
5XW2
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BU of 5xw2 by Molmil
Crystal structure of the Hydroxylase HmtN in C 1 2 1 crystal form
分子名称: Cytochrome P450 107B1 (P450CVIIB1), GLYCEROL, MAGNESIUM ION, ...
著者Zhang, H.D, Zhang, H.J.
登録日2017-06-29
公開日2018-04-25
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.298 Å)
主引用文献Molecular characterization of the hydroxylase HmtN at 1.3 angstrom resolution.
Biochem. Biophys. Res. Commun., 2017
3HI6
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BU of 3hi6 by Molmil
Crystal structure of intermediate affinity I domain of integrin LFA-1 with the Fab fragment of its antibody AL-57
分子名称: Heavy chain of Fab fragment of AL-57 against alpha L I domain, Integrin alpha-L, MANGANESE (II) ION, ...
著者Zhang, H, Wang, J.
登録日2009-05-19
公開日2009-09-22
最終更新日2021-10-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural basis of activation-dependent binding of ligand-mimetic antibody AL-57 to integrin LFA-1.
Proc.Natl.Acad.Sci.USA, 106, 2009
4ZUD
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Crystal Structure of Human Angiotensin Receptor in Complex with Inverse Agonist Olmesartan at 2.8A resolution.
分子名称: Chimera protein of Soluble cytochrome b562 and Type-1 angiotensin II receptor, Olmesartan
著者Zhang, H, Unal, H, Desnoyer, R, Han, G.W, Patel, N, Katritch, V, Karnik, S.S, Cherezov, V, Stevens, R.C, GPCR Network (GPCR)
登録日2015-05-15
公開日2015-10-07
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural Basis for Ligand Recognition and Functional Selectivity at Angiotensin Receptor.
J.Biol.Chem., 290, 2015
4MM0
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BU of 4mm0 by Molmil
Crystal Structure Analysis of the Putative Thioether Synthase SgvP Involved in the Tailoring Step of Griseoviridin
分子名称: P450-like monooxygenase, PROTOPORPHYRIN IX CONTAINING FE
著者Zhang, H, Huang, L, Yi, M, Cai, T, Zhang, H.
登録日2013-09-07
公開日2014-09-17
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural Analysis of SgvP: a Putative Thioether Synthase Involved in the Tailoring Step of Griseoviridin
To be Published
5Z5T
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The first bromodomain of BRD4 with compound BDF-2141
分子名称: 2-amino-4-(1H-imidazol-1-yl)quinolin-8-ol, Bromodomain-containing protein 4
著者Zhang, H, Luo, C.
登録日2018-01-20
公開日2019-01-23
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.991 Å)
主引用文献Development and evaluation of a novel series of Nitroxoline-derived BET inhibitors with antitumor activity in renal cell carcinoma.
Oncogenesis, 7, 2018
5Z5V
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The first bromodomain of BRD4 with compound BDF-1253
分子名称: Bromodomain-containing protein 4, N-{8-hydroxy-4-[(1H-imidazol-1-yl)methyl]quinolin-2-yl}acetamide
著者Zhang, H, Luo, C.
登録日2018-01-20
公開日2019-01-23
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.66 Å)
主引用文献Development and evaluation of a novel series of Nitroxoline-derived BET inhibitors with antitumor activity in renal cell carcinoma.
Oncogenesis, 7, 2018
5Z5U
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The first bromodomain of BRD4 with compound BDF-2254
分子名称: 2-amino-4-(1H-imidazol-1-yl)quinoline-6,8-diol, Bromodomain-containing protein 4
著者Zhang, H, Luo, C.
登録日2018-01-20
公開日2019-01-23
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.631 Å)
主引用文献Development and evaluation of a novel series of Nitroxoline-derived BET inhibitors with antitumor activity in renal cell carcinoma.
Oncogenesis, 7, 2018

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