5GRM

Crystal structure of rat STING in complex with cyclic GMP-AMP with 2'5'and 3'5'phosphodiester linkage(2'3'-cGAMP)

Summary for 5GRM

• Entry DOI: 10.2210/pdb5grm/pdb
• Descriptor: Stimulator of interferon genes protein, cGAMP (3 entities in total)
• Functional Keywords: rat sting, 2'3'-cgamp, immune system
• Biological source: Rattus norvegicus (Rat)
• Cellular location: Endoplasmic reticulum membrane ; Multi-pass membrane protein : F1M391
• Total number of polymer chains: 2
• Total formula weight: 48546.24

Authors

Zhang, H.,Han, M.J.,Tao, J.L.,Ye, Z.Y.,Du, X.X.,Deng, M.J.,Zhang, X.Y.,Li, L.F.,Jiang, Z.F.,Su, X.D. (deposition date: 2016-08-11, release date: 2017-10-25, Last modification date: 2023-11-08)

• Primary citation: Zhang, H.,Han, M.J.,Tao, J.L.,Ye, Z.Y.,Du, X.X.,Deng, M.J.,Zhang, X.Y.,Li, L.F.,Jiang, Z.F.,Su, X.D.; Crystal structure of rat STING in complex with cyclic GMP-AMP with 2'5'and 3'5'phosphodiester linkage(2'3'-cGAMP); To Be Published,

Experimental method

X-RAY DIFFRACTION (1.55 Å)