3BN3

crystal structure of ICAM-5 in complex with aL I domain

Summary for 3BN3

• Entry DOI: 10.2210/pdb3bn3/pdb
• Descriptor: Integrin alpha-L, Intercellular adhesion molecule 5, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total)
• Functional Keywords: icam-5, i domain, integrin, allosteric mobility, cell adhesion, immune system
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 44165.56

Authors

Zhang, H.,Springer, T.A.,Wang, J.-h. (deposition date: 2007-12-13, release date: 2008-08-19, Last modification date: 2023-08-30)

• Primary citation: Zhang, H.,Casasnovas, J.M.,Jin, M.,Liu, J.H.,Gahmberg, C.G.,Springer, T.A.,Wang, J.-h.; An unusual allosteric mobility of the C-terminal helix of a high-affinity alpha L integrin I domain variant bound to ICAM-5; Mol.Cell, 31:432-437, 2008; PubMed: 18691975; DOI: 10.1016/j.molcel.2008.06.022

Experimental method

X-RAY DIFFRACTION (2.099 Å)