4U85
 
 | | Human Pin1 with cysteine sulfinic acid 113 | | 分子名称: | POLYETHYLENE GLYCOL (N=34), Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | | 著者 | Li, W, Zhang, Y. | | 登録日 | 2014-08-01 | | 公開日 | 2015-04-08 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Pin1 cysteine-113 oxidation inhibits its catalytic activity and cellular function in Alzheimer's disease.
Neurobiol.Dis., 76, 2015
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5XKY
 | | Crystal structure of DddY Se derivative | | 分子名称: | Uncharacterized protein, ZINC ION | | 著者 | Li, C.Y, Zhang, Y.Z. | | 登録日 | 2017-05-10 | | 公開日 | 2017-11-01 | | 最終更新日 | 2018-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.303 Å) | | 主引用文献 | Mechanistic Insights into Dimethylsulfoniopropionate Lyase DddY, a New Member of the Cupin Superfamily.
J. Mol. Biol., 429, 2017
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7O6E
 | | 2.12 A cryo-EM structure of Mycobacterium tuberculosis Ferritin | | 分子名称: | Ferritin BfrB | | 著者 | Gijsbers, A, Zhang, Y, Gao, Y, Peters, P.J, Ravelli, R.B.G. | | 登録日 | 2021-04-10 | | 公開日 | 2021-05-19 | | 最終更新日 | 2021-09-15 | | 実験手法 | ELECTRON MICROSCOPY (2.1 Å) | | 主引用文献 | Mycobacterium tuberculosis ferritin: a suitable workhorse protein for cryo-EM development.
Acta Crystallogr D Struct Biol, 77, 2021
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7M59
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1FRP
 | | CRYSTAL STRUCTURE OF FRUCTOSE-1,6-BISPHOSPHATASE COMPLEXED WITH FRUCTOSE-2,6-BISPHOSPHATE, AMP AND ZN2+ AT 2.0 ANGSTROMS RESOLUTION. ASPECTS OF SYNERGISM BETWEEN INHIBITORS | | 分子名称: | 2,6-di-O-phosphono-beta-D-fructofuranose, ADENOSINE MONOPHOSPHATE, FRUCTOSE 1,6-BISPHOSPHATASE, ... | | 著者 | Xue, Y, Huang, S, Liang, J.-Y, Zhang, Y, Lipscomb, W.N. | | 登録日 | 1994-08-26 | | 公開日 | 1994-11-30 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal structure of fructose-1,6-bisphosphatase complexed with fructose 2,6-bisphosphate, AMP, and Zn2+ at 2.0-A resolution: aspects of synergism between inhibitors.
Proc.Natl.Acad.Sci.USA, 91, 1994
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6PB0
 | | Cryo-EM structure of Urocortin 1-bound Corticotropin-releasing factor 1 receptor in complex with Gs protein and Nb35 | | 分子名称: | CHOLESTEROL, Corticotropin-releasing factor receptor 1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | 著者 | Ma, S, Shen, Q, Zhao, L.-H, Mao, C, Zhou, X.E, Shen, D.-D, de Waal, P.W, Bi, P, Li, C, Jiang, Y, Wang, M.-W, Sexton, P.M, Wootten, D, Melcher, K, Zhang, Y, Xu, H.E. | | 登録日 | 2019-06-12 | | 公開日 | 2020-02-12 | | 最終更新日 | 2020-02-19 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Molecular Basis for Hormone Recognition and Activation of Corticotropin-Releasing Factor Receptors.
Mol.Cell, 77, 2020
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4U84
 | | Human Pin1 with S-hydroxyl-cysteine 113 | | 分子名称: | POLYETHYLENE GLYCOL (N=34), Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | | 著者 | Li, W, Zhang, Y. | | 登録日 | 2014-08-01 | | 公開日 | 2015-04-08 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | | 主引用文献 | Pin1 cysteine-113 oxidation inhibits its catalytic activity and cellular function in Alzheimer's disease.
Neurobiol.Dis., 76, 2015
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8QQK
 | | Cryo-EM structure of E. coli cytochrome bo3 quinol oxidase assembled in peptidiscs | | 分子名称: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 1,2-Distearoyl-sn-glycerophosphoethanolamine, COPPER (II) ION, ... | | 著者 | Gao, Y, Zhang, Y, Hakke, S, Peters, P.J, Ravelli, R.B.G. | | 登録日 | 2023-10-05 | | 公開日 | 2024-04-24 | | 最終更新日 | 2024-05-01 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | Cryo-EM structure of cytochrome bo 3 quinol oxidase assembled in peptidiscs reveals an "open" conformation for potential ubiquinone-8 release.
Biochim Biophys Acta Bioenerg, 1865, 2024
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4KQZ
 | | structure of the receptor binding domain (RBD) of MERS-CoV spike | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, S protein | | 著者 | Lu, G, Hu, Y, Wang, Q, Qi, J, Gao, F, Li, Y, Zhang, Y, Zhang, W, Yuan, Y, Bao, J, Zhang, B, Shi, Y, Yan, J, Gao, G.F. | | 登録日 | 2013-05-15 | | 公開日 | 2013-07-10 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.514 Å) | | 主引用文献 | Molecular basis of binding between novel human coronavirus MERS-CoV and its receptor CD26.
Nature, 500, 2013
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5XKX
 | | Crystal structure of WT DddY | | 分子名称: | ACETATE ION, Uncharacterized protein, ZINC ION | | 著者 | Li, C.Y, Zhang, Y.Z. | | 登録日 | 2017-05-10 | | 公開日 | 2017-11-01 | | 最終更新日 | 2018-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Mechanistic Insights into Dimethylsulfoniopropionate Lyase DddY, a New Member of the Cupin Superfamily.
J. Mol. Biol., 429, 2017
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4KR0
 | | Complex structure of MERS-CoV spike RBD bound to CD26 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Dipeptidyl peptidase 4, ... | | 著者 | Lu, G, Hu, Y, Wang, Q, Qi, J, Gao, F, Li, Y, Zhang, Y, Zhang, W, Yuan, Y, Zhang, B, Shi, Y, Yan, J, Gao, G.F. | | 登録日 | 2013-05-15 | | 公開日 | 2013-07-10 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.702 Å) | | 主引用文献 | Molecular basis of binding between novel human coronavirus MERS-CoV and its receptor CD26.
Nature, 500, 2013
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5TOU
 | | STRUCTURE OF C-PHYCOCYANIN FROM ARCTIC PSEUDANABAENA SP. LW0831 | | 分子名称: | PHYCOCYANOBILIN, Phycocyanin alpha-1 subunit, Phycocyanin beta-1 subunit | | 著者 | Wang, Q.M, Li, C.Y, Su, H.N, Zhang, Y.Z, Xie, B.B. | | 登録日 | 2016-10-18 | | 公開日 | 2017-03-08 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.04 Å) | | 主引用文献 | Structural insights into the cold adaptation of the photosynthetic pigment-protein C-phycocyanin from an Arctic cyanobacterium
Biochim. Biophys. Acta, 1858, 2017
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1FPG
 | | STRUCTURAL ASPECTS OF THE ALLOSTERIC INHIBITION OF FRUCTOSE-1,6-BISPHOSPHATASE BY AMP: THE BINDING OF BOTH THE SUBSTRATE ANALOGUE 2,5-ANHYDRO-D-GLUCITOL-1,6-BISPHOSPHATE AND CATALYTIC METAL IONS MONITORED BY X-RAY CRYSTALLOGRAPHY | | 分子名称: | 2,5-anhydro-1,6-di-O-phosphono-D-glucitol, ADENOSINE MONOPHOSPHATE, FRUCTOSE 1,6-BISPHOSPHATASE, ... | | 著者 | Villeret, V, Huang, S, Zhang, Y, Lipscomb, W.N. | | 登録日 | 1994-12-15 | | 公開日 | 1995-02-27 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structural aspects of the allosteric inhibition of fructose-1,6-bisphosphatase by AMP: the binding of both the substrate analogue 2,5-anhydro-D-glucitol 1,6-bisphosphate and catalytic metal ions monitored by X-ray crystallography.
Biochemistry, 34, 1995
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1F75
 | | CRYSTAL STRUCTURE OF UNDECAPRENYL DIPHOSPHATE SYNTHASE FROM MICROCOCCUS LUTEUS B-P 26 | | 分子名称: | SULFATE ION, UNDECAPRENYL PYROPHOSPHATE SYNTHETASE | | 著者 | Fujihashi, M, Zhang, Y.-W, Higuchi, Y, Li, X.-Y, Koyama, T, Miki, K. | | 登録日 | 2000-06-26 | | 公開日 | 2001-03-28 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Crystal structure of cis-prenyl chain elongating enzyme, undecaprenyl diphosphate synthase.
Proc.Natl.Acad.Sci.USA, 98, 2001
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7P13
 | | 2.29 A Mycobacterium tuberculosis EspB. | | 分子名称: | ESX-1 secretion-associated protein EspB | | 著者 | Gijsbers, A, Zhang, Y, Vinciauskaite, V, Siroy, A, Gao, Y, Tria, G, Mathew, A, Sanchez-Puig, N, Lopez-Iglesias, C, Peters, P.J, Ravelli, R.B.G. | | 登録日 | 2021-07-01 | | 公開日 | 2021-08-18 | | 最終更新日 | 2021-10-13 | | 実験手法 | ELECTRON MICROSCOPY (2.29 Å) | | 主引用文献 | Priming mycobacterial ESX-secreted protein B to form a channel-like structure.
Curr Res Struct Biol, 3, 2021
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8KC7
 | | Rpd3S histone deacetylase complex | | 分子名称: | Chromatin modification-related protein EAF3, Histone deacetylase RPD3, Transcriptional regulatory protein RCO1, ... | | 著者 | Dong, S, Li, H, Wang, M, Rasheed, N, Zou, B, Gao, X, Guan, J, Li, W, Zhang, J, Wang, C, Zhou, N, Shi, X, Li, M, Zhou, M, Huang, J, Li, H, Zhang, Y, Wong, K.H, Zhang, X, Chao, W.C.H, He, J. | | 登録日 | 2023-08-06 | | 公開日 | 2023-09-13 | | 最終更新日 | 2023-10-18 | | 実験手法 | ELECTRON MICROSCOPY (3.46 Å) | | 主引用文献 | Structural basis of nucleosome deacetylation and DNA linker tightening by Rpd3S histone deacetylase complex.
Cell Res., 33, 2023
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8KI5
 | | PhmA, a type I diterpene synthase without NST/DTE motif | | 分子名称: | (2Z,6Z)-3,7,11-trimethyldodeca-2,6,10-trien-1-ol, PhmA | | 著者 | Zhang, B, Ge, H.M, Zhu, A, Zhang, Y. | | 登録日 | 2023-08-22 | | 公開日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | | 主引用文献 | Biosynthesis of Platelet Activating Factor Antagonist Phomactins Revealing a New Class of Type I Diterpene Synthase
To Be Published
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7Y0V
 | | The co-crystal structure of BA.1-RBD with Fab-5549 | | 分子名称: | 5549-Fab, Spike protein S1, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | | 著者 | Xiao, J.Y, Zhang, Y. | | 登録日 | 2022-06-06 | | 公開日 | 2022-09-28 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.48 Å) | | 主引用文献 | Rational identification of potent and broad sarbecovirus-neutralizing antibody cocktails from SARS convalescents.
Cell Rep, 41, 2022
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7JVR
 | | Cryo-EM structure of Bromocriptine-bound dopamine receptor 2 in complex with Gi protein | | 分子名称: | Antibody fragment ScFv16, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | 著者 | Zhuang, Y, Xu, P, Mao, C, Wang, L, Krumm, B, Zhou, X.E, Huang, S, Liu, H, Cheng, X, Huang, X.-P, Sheng, D.-D, Xu, T, Liu, Y.-F, Wang, Y, Guo, J, Jiang, Y, Jiang, H, Melcher, K, Roth, B.L, Zhang, Y, Zhang, C, Xu, H.E. | | 登録日 | 2020-08-22 | | 公開日 | 2021-02-24 | | 最終更新日 | 2021-03-31 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | Structural insights into the human D1 and D2 dopamine receptor signaling complexes.
Cell, 184, 2021
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5WTB
 | | Complex Structure of Staphylococcus aureus SdrE with human complement factor H | | 分子名称: | Peptide from Complement factor H, Serine-aspartate repeat-containing protein E | | 著者 | Wu, M, Zhang, Y, Hang, T, Wang, C, Yang, Y, Zang, J, Zhang, M, Zhang, X. | | 登録日 | 2016-12-10 | | 公開日 | 2017-07-19 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | Staphylococcus aureus SdrE captures complement factor H's C-terminus via a novel 'close, dock, lock and latch' mechanism for complement evasion
Biochem. J., 474, 2017
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6K7Z
 | | Crystal structure of a GH18 chitinase from Pseudoalteromonas aurantia | | 分子名称: | GH18 chiitnase | | 著者 | Wang, Y.J, Li, P.Y, Cao, H.Y, Chen, X.L, Zhang, Y.Z. | | 登録日 | 2019-06-10 | | 公開日 | 2020-06-10 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.799 Å) | | 主引用文献 | Structural Insight Into Chitin Degradation and Thermostability of a Novel Endochitinase From the Glycoside Hydrolase Family 18.
Front Microbiol, 10, 2019
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6OGM
 | | Crystal structure of apo unFused 4-OT | | 分子名称: | 4-oxalocrotonate tautomerase, GLYCEROL | | 著者 | Medellin, B.P, Whitman, C.P, Zhang, Y.J. | | 登録日 | 2019-04-03 | | 公開日 | 2020-02-26 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.865 Å) | | 主引用文献 | Structural, Kinetic, and Mechanistic Analysis of an Asymmetric 4-Oxalocrotonate Tautomerase Trimer.
Biochemistry, 58, 2019
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6UTS
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6KYF
 | | Crystal structure of an anti-CRISPR protein | | 分子名称: | AcrF11, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | | 著者 | Niu, Y, Wang, H, Zhang, Y, Feng, Y. | | 登録日 | 2019-09-18 | | 公開日 | 2020-09-23 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (3.07 Å) | | 主引用文献 | A Type I-F Anti-CRISPR Protein Inhibits the CRISPR-Cas Surveillance Complex by ADP-Ribosylation.
Mol.Cell, 80, 2020
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3JAU
 | | The cryoEM map of EV71 mature viron in complex with the Fab fragment of antibody D5 | | 分子名称: | Capsid protein VP1, Heavy chain of Fab fragment variable region of antibody D5, Light chain of Fab fragment variable region of antibody D5 | | 著者 | Fan, C, Ye, X.H, Ku, Z.Q, Zuo, T, Kong, L.L, Zhang, C, Shi, J.P, Liu, Q.W, Chen, T, Zhang, Y.Y, Jiang, W, Zhang, L.Q, Huang, Z, Cong, Y. | | 登録日 | 2015-06-24 | | 公開日 | 2016-02-10 | | 最終更新日 | 2019-12-18 | | 実験手法 | ELECTRON MICROSCOPY (4.8 Å) | | 主引用文献 | Structural Basis for Recognition of Human Enterovirus 71 by a Bivalent Broadly Neutralizing Monoclonal Antibody
Plos Pathog., 12, 2016
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