4S25
Crystal structure of Arabidopsis thaliana ThiC with bound imidazole ribonucleotide, S-adenosylhomocysteine, Fe4S4 cluster and Zn (trigonal crystal form)
Summary for 4S25
Entry DOI | 10.2210/pdb4s25/pdb |
Related | 3EPM 3EPN 3EPO 4N7Q 4S26 4S27 4S28 4S29 4S2A |
Descriptor | Phosphomethylpyrimidine synthase, chloroplastic, IRON/SULFUR CLUSTER, 1-(5-O-phosphono-beta-D-ribofuranosyl)-1H-imidazole, ... (8 entities in total) |
Functional Keywords | alpha-beta barrel, radical sam superfamily, iron-sulfur cluster, thiamin, vitamin b1, vitamin b12, domain swapping, adomet and glutamate mutase, lyase |
Biological source | Arabidopsis thaliana (mouse-ear cress,thale-cress) |
Cellular location | Plastid, chloroplast stroma : O82392 |
Total number of polymer chains | 1 |
Total formula weight | 65967.42 |
Authors | Fenwick, M.K.,Mehta, A.P.,Zhang, Y.,Abdelwahed, S.,Begley, T.P.,Ealick, S.E. (deposition date: 2015-01-19, release date: 2015-04-08, Last modification date: 2023-09-20) |
Primary citation | Fenwick, M.K.,Mehta, A.P.,Zhang, Y.,Abdelwahed, S.H.,Begley, T.P.,Ealick, S.E. Non-canonical active site architecture of the radical SAM thiamin pyrimidine synthase. Nat Commun, 6:6480-6480, Cited by PubMed: 25813242DOI: 10.1038/ncomms7480 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.45 Å) |
Structure validation
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