4S2A
Crystal structure of Caulobacter crescentus ThiC with Fe4S4 cluster at remote site (holo form)
Summary for 4S2A
| Entry DOI | 10.2210/pdb4s2a/pdb |
| Related | 3EPM 3EPN 3EPO 4N7Q 4S25 4S26 4S27 4S28 4S29 |
| Descriptor | Phosphomethylpyrimidine synthase, IRON/SULFUR CLUSTER, PHOSPHATE ION (3 entities in total) |
| Functional Keywords | alpha-beta barrel, radical sam superfamily, iron-sulfur cluster, thiamin, vitamin b1, vitamin b12, domain swapping, adomet and glutamate mutase, lyase |
| Biological source | Caulobacter crescentus CB15 |
| Total number of polymer chains | 1 |
| Total formula weight | 68697.95 |
| Authors | Fenwick, M.K.,Mehta, A.P.,Zhang, Y.,Abdelwahed, S.,Begley, T.P.,Ealick, S.E. (deposition date: 2015-01-19, release date: 2015-04-08, Last modification date: 2023-09-20) |
| Primary citation | Fenwick, M.K.,Mehta, A.P.,Zhang, Y.,Abdelwahed, S.H.,Begley, T.P.,Ealick, S.E. Non-canonical active site architecture of the radical SAM thiamin pyrimidine synthase. Nat Commun, 6:6480-6480, Cited by PubMed: 25813242DOI: 10.1038/ncomms7480 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.93 Å) |
Structure validation
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