4S2A

Crystal structure of Caulobacter crescentus ThiC with Fe4S4 cluster at remote site (holo form)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005829	cellular_component	cytosol
A	0008270	molecular_function	zinc ion binding
A	0009228	biological_process	thiamine biosynthetic process
A	0009229	biological_process	thiamine diphosphate biosynthetic process
A	0016829	molecular_function	lyase activity
A	0016830	molecular_function	carbon-carbon lyase activity
A	0046872	molecular_function	metal ion binding
A	0051536	molecular_function	iron-sulfur cluster binding
A	0051539	molecular_function	4 iron, 4 sulfur cluster binding
A	0070284	molecular_function	4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE SF4 A 700

Chain	Residue
A	PRO322
A	HIS347
A	CYS561
A	CYS564
A	PHE568
A	CYS569

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site_id	AC2
Number of Residues	7
Details	BINDING SITE FOR RESIDUE PO4 A 701

Chain	Residue
A	ARG334
A	GLY335
A	ASP374
A	ARG377
A	TYR277
A	HIS313
A	SER333

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	8
Details	BINDING: BINDING => ECO:0000269|PubMed:18953358, ECO:0007744|PDB:3EPN

Chain	Residue	Details
A	ASN219
A	MET248
A	TYR277
A	HIS313
A	SER333
A	ASP374
A	GLU413
A	TYR440

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site_id	SWS_FT_FI2
Number of Residues	2
Details	BINDING: BINDING => ECO:0000269|PubMed:18953358, ECO:0007744|PDB:3EPM

Chain	Residue	Details
A	HIS417
A	HIS481

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site_id	SWS_FT_FI3
Number of Residues	3
Details	BINDING: BINDING => ECO:0000269|PubMed:25813242, ECO:0007744|PDB:4S2A

Chain	Residue	Details
A	CYS561
A	CYS564
A	CYS569

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