4S2A
Crystal structure of Caulobacter crescentus ThiC with Fe4S4 cluster at remote site (holo form)
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0005829 | cellular_component | cytosol |
A | 0008270 | molecular_function | zinc ion binding |
A | 0009228 | biological_process | thiamine biosynthetic process |
A | 0009229 | biological_process | thiamine diphosphate biosynthetic process |
A | 0016829 | molecular_function | lyase activity |
A | 0016830 | molecular_function | carbon-carbon lyase activity |
A | 0046872 | molecular_function | metal ion binding |
A | 0051536 | molecular_function | iron-sulfur cluster binding |
A | 0051539 | molecular_function | 4 iron, 4 sulfur cluster binding |
A | 0070284 | molecular_function | 4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase activity |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE SF4 A 700 |
Chain | Residue |
A | PRO322 |
A | HIS347 |
A | CYS561 |
A | CYS564 |
A | PHE568 |
A | CYS569 |
site_id | AC2 |
Number of Residues | 7 |
Details | BINDING SITE FOR RESIDUE PO4 A 701 |
Chain | Residue |
A | ARG334 |
A | GLY335 |
A | ASP374 |
A | ARG377 |
A | TYR277 |
A | HIS313 |
A | SER333 |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 8 |
Details | BINDING: BINDING => ECO:0000269|PubMed:18953358, ECO:0007744|PDB:3EPN |
Chain | Residue | Details |
A | ASN219 | |
A | MET248 | |
A | TYR277 | |
A | HIS313 | |
A | SER333 | |
A | ASP374 | |
A | GLU413 | |
A | TYR440 |
site_id | SWS_FT_FI2 |
Number of Residues | 2 |
Details | BINDING: BINDING => ECO:0000269|PubMed:18953358, ECO:0007744|PDB:3EPM |
Chain | Residue | Details |
A | HIS417 | |
A | HIS481 |
site_id | SWS_FT_FI3 |
Number of Residues | 3 |
Details | BINDING: BINDING => ECO:0000269|PubMed:25813242, ECO:0007744|PDB:4S2A |
Chain | Residue | Details |
A | CYS561 | |
A | CYS564 | |
A | CYS569 |