8XZJ
Cryo-EM structure of the WN353-bound human APLNR-Gi complex
Summary for 8XZJ
Entry DOI | 10.2210/pdb8xzj/pdb |
EMDB information | 38798 |
Descriptor | Apelin receptor, Guanine nucleotide-binding protein G(i) subunit alpha-1, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... (6 entities in total) |
Functional Keywords | aplnr, class a gpcr, synthetic peptide, membrane protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 6 |
Total formula weight | 156479.82 |
Authors | |
Primary citation | Wang, W.W.,Ji, S.Y.,Zhang, W.,Zhang, J.,Cai, C.,Hu, R.,Zang, S.K.,Miao, L.,Xu, H.,Chen, L.N.,Yang, Z.,Guo, J.,Qin, J.,Shen, D.D.,Liang, P.,Zhang, Y.,Zhang, Y. Structure-based design of non-hypertrophic apelin receptor modulator. Cell, 187:1460-1475.e20, 2024 Cited by PubMed: 38428423DOI: 10.1016/j.cell.2024.02.004 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3 Å) |
Structure validation
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