7XT1
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7YC8
| Cryo-EM structure of Tetrahymena ribozyme conformation 1 undergoing the first-step self-splicing | Descriptor: | GUANOSINE-5'-TRIPHOSPHATE, RNA (388-MER) | Authors: | Zhang, X, Li, S, Pintilie, G, Palo, M.Z, Zhang, K. | Deposit date: | 2022-07-01 | Release date: | 2023-07-05 | Last modified: | 2023-08-16 | Method: | ELECTRON MICROSCOPY (4.14 Å) | Cite: | Snapshots of the first-step self-splicing of Tetrahymena ribozyme revealed by cryo-EM. Nucleic Acids Res., 51, 2023
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7YCG
| Cryo-EM structure of Tetrahymena ribozyme conformation 2 undergoing the first-step self-splicing | Descriptor: | GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, RNA (393-MER), ... | Authors: | Zhang, X, Li, S, Pintilie, G, Palo, M.Z, Zhang, K. | Deposit date: | 2022-07-01 | Release date: | 2023-07-05 | Last modified: | 2023-08-16 | Method: | ELECTRON MICROSCOPY (3.18 Å) | Cite: | Snapshots of the first-step self-splicing of Tetrahymena ribozyme revealed by cryo-EM. Nucleic Acids Res., 51, 2023
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7YCI
| Cryo-EM structure of Tetrahymena ribozyme conformation 4 undergoing the first-step self-splicing | Descriptor: | GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, RNA (389-MER), ... | Authors: | Zhang, X, Li, S, Pintilie, G, Palo, M.Z, Zhang, K. | Deposit date: | 2022-07-01 | Release date: | 2023-07-05 | Last modified: | 2023-08-16 | Method: | ELECTRON MICROSCOPY (2.98 Å) | Cite: | Snapshots of the first-step self-splicing of Tetrahymena ribozyme revealed by cryo-EM. Nucleic Acids Res., 51, 2023
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7YCH
| Cryo-EM structure of Tetrahymena ribozyme conformation 3 undergoing the first-step self-splicing | Descriptor: | GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, RNA (393-MER), ... | Authors: | Zhang, X, Li, S, Pintilie, G, Palo, M.Z, Zhang, K. | Deposit date: | 2022-07-01 | Release date: | 2023-07-05 | Last modified: | 2023-08-16 | Method: | ELECTRON MICROSCOPY (3.09 Å) | Cite: | Snapshots of the first-step self-splicing of Tetrahymena ribozyme revealed by cryo-EM. Nucleic Acids Res., 51, 2023
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5Z1V
| Crystal structure of AvrPib | Descriptor: | AvrPib protein | Authors: | Zhang, X, He, D, Zhao, Y.X, Taylor, I.A, Peng, Y.L, Yang, J, Liu, J.F. | Deposit date: | 2017-12-28 | Release date: | 2018-09-05 | Last modified: | 2018-10-03 | Method: | X-RAY DIFFRACTION (1.661 Å) | Cite: | A positive-charged patch and stabilized hydrophobic core are essential for avirulence function of AvrPib in the rice blast fungus. Plant J., 96, 2018
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4GJE
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4GJF
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4GJG
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8INB
| Cryo-EM structure of Cas12j-SF05-crRNA-dsDNA complex | Descriptor: | Cas12j-SF05, NTS-DNA, TS-DNA, ... | Authors: | Zhang, X, Duan, Z.Q, Zhu, J.K. | Deposit date: | 2023-03-09 | Release date: | 2024-03-13 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Molecular basis for DNA cleavage by the hypercompact Cas12j-SF05. Cell Discov, 9, 2023
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7F8Y
| Crystal structure of the cholecystokinin receptor CCKAR in complex with devazepide | Descriptor: | N-[(3S)-1-methyl-2-oxidanylidene-5-phenyl-3H-1,4-benzodiazepin-3-yl]-1H-indole-2-carboxamide, fusion protein of Cholecystokinin receptor type A and Endolysin | Authors: | Zhang, X, He, C, Wang, M, Zhou, Q, Yang, D, Zhu, Y, Wu, B, Zhao, Q. | Deposit date: | 2021-07-02 | Release date: | 2021-10-13 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structures of the human cholecystokinin receptors bound to agonists and antagonists. Nat.Chem.Biol., 17, 2021
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7F8U
| Crystal structure of the cholecystokinin receptor CCKAR in complex with lintitript | Descriptor: | 2-[2-[[4-(2-chlorophenyl)-1,3-thiazol-2-yl]carbamoyl]indol-1-yl]ethanoic acid, Fusion protein of Cholecystokinin receptor type A and Endolysin | Authors: | Zhang, X, He, C, Wang, M, Zhou, Q, Yang, D, Zhu, Y, Wu, B, Zhao, Q. | Deposit date: | 2021-07-02 | Release date: | 2021-10-13 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structures of the human cholecystokinin receptors bound to agonists and antagonists. Nat.Chem.Biol., 17, 2021
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7F8X
| Crystal structure of the cholecystokinin receptor CCKAR in complex with NN9056 | Descriptor: | ASP-SMF-NLE-GLY-TRP-NLE-OEM-MEA-NH2 (NN9056), Cholecystokinin receptor type A,Endolysin | Authors: | Zhang, X, He, C, Wang, M, Zhou, Q, Yang, D, Zhu, Y, Wu, B, Zhao, Q. | Deposit date: | 2021-07-02 | Release date: | 2021-12-29 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structures of the human cholecystokinin receptors bound to agonists and antagonists. Nat.Chem.Biol., 17, 2021
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7CBQ
| Crystal structure of PDE4D catalytic domain in complex with Apremilast | Descriptor: | 1,2-ETHANEDIOL, MAGNESIUM ION, N-{2-[(1S)-1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl]-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl}acetamide, ... | Authors: | Zhang, X.L, Xu, Y.C. | Deposit date: | 2020-06-13 | Release date: | 2021-01-27 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.59 Å) | Cite: | Design, synthesis, and biological evaluation of tetrahydroisoquinolines derivatives as novel, selective PDE4 inhibitors for antipsoriasis treatment. Eur.J.Med.Chem., 211, 2021
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4DXW
| Crystal structure of NavRh, a voltage-gated sodium channel | Descriptor: | 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, CALCIUM ION, Ion transport protein, ... | Authors: | Zhang, X, Ren, W.L, Yan, C.Y, Wang, J.W, Yan, N. | Deposit date: | 2012-02-28 | Release date: | 2012-05-23 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (3.052 Å) | Cite: | Crystal structure of an orthologue of the NaChBac voltage-gated sodium channel Nature, 486, 2012
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7CBJ
| Crystal structure of PDE4D catalytic domain in complex with compound 36 | Descriptor: | (1S)-1-[(7-chloranyl-1H-indol-3-yl)methyl]-6,7-dimethoxy-3,4-dihydro-1H-isoquinoline-2-carbaldehyde, 1,2-ETHANEDIOL, MAGNESIUM ION, ... | Authors: | Zhang, X.L, Xu, Y.C. | Deposit date: | 2020-06-12 | Release date: | 2021-06-16 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Design, synthesis, and biological evaluation of tetrahydroisoquinolines derivatives as novel, selective PDE4 inhibitors for antipsoriasis treatment. Eur.J.Med.Chem., 211, 2021
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6LSV
| Crystal structure of JOX2 in complex with 2OG, Fe, and JA | Descriptor: | 2-OXOGLUTARIC ACID, FE (III) ION, Probable 2-oxoglutarate-dependent dioxygenase At5g05600, ... | Authors: | Zhang, X, Wang, D, Liu, J. | Deposit date: | 2020-01-20 | Release date: | 2021-02-10 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.651 Å) | Cite: | Structure-guided analysis of Arabidopsis JASMONATE-INDUCED OXYGENASE (JOX) 2 reveals key residues for recognition of jasmonic acid substrate by plant JOXs. Mol Plant, 14, 2021
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2GS6
| Crystal Structure of the active EGFR kinase domain in complex with an ATP analog-peptide conjugate | Descriptor: | CHLORIDE ION, Epidermal growth factor receptor, Peptide, ... | Authors: | Zhang, X, Gureasko, J, Shen, K, Cole, P.A, Kuriyan, J. | Deposit date: | 2006-04-25 | Release date: | 2006-06-20 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | An Allosteric Mechanism for Activation of the Kinase Domain of Epidermal Growth Factor Receptor Cell(Cambridge,Mass.), 125, 2006
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2MQ0
| NMR structure of the c3 domain of human cardiac myosin binding protein-c | Descriptor: | Myosin-binding protein C, cardiac-type | Authors: | Zhang, X, De, S, Mcintosh, L.P, Paetzel, M. | Deposit date: | 2014-06-10 | Release date: | 2014-07-30 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Structural Characterization of the C3 Domain of Cardiac Myosin Binding Protein C and Its Hypertrophic Cardiomyopathy-Related R502W Mutant. Biochemistry, 53, 2014
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2MQ3
| NMR structure of the c3 domain of human cardiac myosin binding protein-c with a hypertrophic cardiomyopathy-related mutation R502W. | Descriptor: | Myosin-binding protein C, cardiac-type | Authors: | Zhang, X, De, S, Mcintosh, L.P, Paetzel, M. | Deposit date: | 2014-06-12 | Release date: | 2014-07-30 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Structural Characterization of the C3 Domain of Cardiac Myosin Binding Protein C and Its Hypertrophic Cardiomyopathy-Related R502W Mutant. Biochemistry, 53, 2014
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2GS2
| Crystal Structure of the active EGFR kinase domain | Descriptor: | Epidermal growth factor receptor | Authors: | Zhang, X, Gureasko, J, Shen, K, Cole, P.A, Kuriyan, J. | Deposit date: | 2006-04-25 | Release date: | 2006-06-20 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | An allosteric mechanism for activation of the kinase domain of epidermal growth factor receptor. Cell(Cambridge,Mass.), 125, 2006
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7F8V
| Cryo-EM structure of the cholecystokinin receptor CCKBR in complex with gastrin-17 and Gi | Descriptor: | Gastrin-17, Gastrin/cholecystokinin type B receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | Authors: | Zhang, X, He, C, Wang, M, Zhou, Q, Yang, D, Zhu, Y, Wu, B, Zhao, Q. | Deposit date: | 2021-07-02 | Release date: | 2021-10-13 | Last modified: | 2022-02-16 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Structures of the human cholecystokinin receptors bound to agonists and antagonists. Nat.Chem.Biol., 17, 2021
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7F8W
| Cryo-EM structure of the cholecystokinin receptor CCKBR in complex with gastrin-17 and Gq | Descriptor: | Gastrin-17, Gastrin/cholecystokinin type B receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | Authors: | Zhang, X, He, C, Wang, M, Zhou, Q, Yang, D, Zhu, Y, Wu, B, Zhao, Q. | Deposit date: | 2021-07-02 | Release date: | 2021-10-13 | Last modified: | 2022-02-16 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Structures of the human cholecystokinin receptors bound to agonists and antagonists. Nat.Chem.Biol., 17, 2021
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3J4U
| A new topology of the HK97-like fold revealed in Bordetella bacteriophage: non-covalent chainmail secured by jellyrolls | Descriptor: | cementing protein, major capsid protein | Authors: | Zhang, X, Guo, H, Jin, L, Czornyj, E, Hodes, A, Hui, W.H, Nieh, A.W, Miller, J.F, Zhou, Z.H. | Deposit date: | 2013-10-09 | Release date: | 2013-12-25 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | A new topology of the HK97-like fold revealed in Bordetella bacteriophage by cryoEM at 3.5 A resolution. Elife, 2, 2013
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7DY8
| Thermotoga maritima ferritin mutant-FLAL | Descriptor: | CALCIUM ION, FE (III) ION, Ferritin | Authors: | Zhang, X, Zhao, G. | Deposit date: | 2021-01-20 | Release date: | 2021-09-01 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.103 Å) | Cite: | Protein interface redesign facilitates the transformation of nanocage building blocks to 1D and 2D nanomaterials. Nat Commun, 12, 2021
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