5XUR

Crystal Structure of Rv2466c C22S Mutant

Summary for 5XUR

• Entry DOI: 10.2210/pdb5xur/pdb
• Descriptor: Thioredoxin-like reductase Rv2466c, 1,2-ETHANEDIOL, CHLORIDE ION, ... (4 entities in total)
• Functional Keywords: thioredoxin-like, oxidoreductase
• Biological source: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
• Cellular location: Cytoplasm : O53193
• Total number of polymer chains: 4
• Total formula weight: 96575.87

Authors

Zhang, X.,Li, H. (deposition date: 2017-06-25, release date: 2018-03-14, Last modification date: 2023-11-22)

• Primary citation: Negri, A.,Javidnia, P.,Mu, R.,Zhang, X.,Vendome, J.,Gold, B.,Roberts, J.,Barman, D.,Ioerger, T.,Sacchettini, J.C.,Jiang, X.,Burns-Huang, K.,Warrier, T.,Ling, Y.,Warren, J.D.,Oren, D.A.,Beuming, T.,Wang, H.,Wu, J.,Li, H.,Rhee, K.Y.,Nathan, C.F.,Liu, G.,Somersan-Karakaya, S.; Identification of a Mycothiol-Dependent Nitroreductase from Mycobacterium tuberculosis.; ACS Infect Dis, 4:771-787, 2018; PubMed: 29465985; DOI: 10.1021/acsinfecdis.7b00111

Experimental method

X-RAY DIFFRACTION (1.996 Å)