5XUR

Crystal Structure of Rv2466c C22S Mutant

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Thioredoxin-like reductase Rv2466c	polymer	215	24104.1	4	UniProt (O53193) Pfam (PF22234)	Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
2	E, G (A, D)	1,2-ETHANEDIOL	non-polymer		62.1	2	Chemie (EDO)
3	F (B)	CHLORIDE ION	non-polymer		35.5	1	Chemie (CL)
4	H, I, J, K (A, B, C, D)	water	water		18.0	448	Chemie (HOH)

Sequence modifications

A, B, C, D: 1 - 207 (UniProt: O53193)

PDB	External Database	Details
Ser 22	Cys 22	engineered mutation
Val 208	-	expression tag
Glu 209	-	expression tag
His 210	-	expression tag
His 211	-	expression tag
His 212	-	expression tag
His 213	-	expression tag
His 214	-	expression tag
His 215	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	96416.3
Non-Polymers*	Number of molecules	3
	Total formula weight	159.6
All*	Total formula weight	96575.9

*Water molecules are not included.