5XWY

Electron cryo-microscopy structure of LbuCas13a-crRNA binary complex

Summary for 5XWY

• Entry DOI: 10.2210/pdb5xwy/pdb
• EMDB information: 6777
• Descriptor: A type VI-A CRISPR-Cas RNA-guided RNA ribonuclease, Cas13a, RNA (59-MER) (2 entities in total)
• Functional Keywords: cas13a, crispr, rna binding protein-rna complex, rna binding protein/rna
• Biological source: Leptotrichia buccalis (strain ATCC 14201 / DSM 1135 / JCM 12969 / NCTC 10249 / C-1013-b); More
• Total number of polymer chains: 2
• Total formula weight: 157424.50

Authors

Zhang, X.,Wang, Y.,Ma, J.,Liu, L.,Li, X.,Li, Z.,You, L.,Wang, J.,Wang, M. (deposition date: 2017-06-30, release date: 2017-09-13, Last modification date: 2024-03-27)

• Primary citation: Liu, L.,Li, X.,Ma, J.,Li, Z.,You, L.,Wang, J.,Wang, M.,Zhang, X.,Wang, Y.; The Molecular Architecture for RNA-Guided RNA Cleavage by Cas13a.; Cell, 170:714-726.e10, 2017; PubMed: 28757251; DOI: 10.1016/j.cell.2017.06.050

Experimental method

ELECTRON MICROSCOPY (3.2 Å)