5XWY
Electron cryo-microscopy structure of LbuCas13a-crRNA binary complex
Functional Information from GO Data
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 10 |
| Details | Region: {"description":"Binds crRNA repeat and spacer","evidences":[{"source":"PubMed","id":"28757251","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 52 |
| Details | Region: {"description":"Binds crRNA repeat","evidences":[{"source":"PubMed","id":"28757251","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 189 |
| Details | Region: {"description":"Helical-1","evidences":[{"source":"PubMed","id":"28757251","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 23 |
| Details | Region: {"description":"Binds crRNA processing site","evidences":[{"source":"PubMed","id":"28757251","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 147 |
| Details | Region: {"description":"HEPN-like fold 1-I","evidences":[{"source":"PubMed","id":"26593719","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"28757251","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 242 |
| Details | Region: {"description":"Helical-2","evidences":[{"source":"PubMed","id":"28757251","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 10 |
| Details | Region: {"description":"Binds target RNA","evidences":[{"source":"PubMed","id":"28757251","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI8 |
| Number of Residues | 31 |
| Details | Region: {"description":"Binds crRNA spacer","evidences":[{"source":"PubMed","id":"28757251","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI9 |
| Number of Residues | 61 |
| Details | Region: {"description":"HEPN-like fold 1-II","evidences":[{"source":"PubMed","id":"28757251","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI10 |
| Number of Residues | 6 |
| Details | Region: {"description":"Binds crRNA spacer and target RNA","evidences":[{"source":"PubMed","id":"28757251","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI11 |
| Number of Residues | 132 |
| Details | Region: {"description":"Linker","evidences":[{"source":"PubMed","id":"28757251","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI12 |
| Number of Residues | 3 |
| Details | Region: {"description":"Binds 3'-end of target RNA, in adjacent protein","evidences":[{"source":"PubMed","id":"28757251","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI13 |
| Number of Residues | 66 |
| Details | Coiled coil: {"evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI14 |
| Number of Residues | 4 |
| Details | Active site: {"description":"For target RNA cleavage","evidences":[{"source":"PubMed","id":"27669025","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI15 |
| Number of Residues | 4 |
| Details | Site: {"description":"Binds target RNA","evidences":[{"source":"PubMed","id":"28757251","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI16 |
| Number of Residues | 2 |
| Details | Site: {"description":"Binds crRNA repeat","evidences":[{"source":"PubMed","id":"28757251","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI17 |
| Number of Residues | 1 |
| Details | Site: {"description":"Binds 3'-end of target RNA, in adjacent protein","evidences":[{"source":"PubMed","id":"28757251","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI18 |
| Number of Residues | 3 |
| Details | Site: {"description":"Binds crRNA spacer","evidences":[{"source":"PubMed","id":"28757251","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
