2MQ3

NMR structure of the c3 domain of human cardiac myosin binding protein-c with a hypertrophic cardiomyopathy-related mutation R502W.

Summary for 2MQ3

• Entry DOI: 10.2210/pdb2mq3/pdb
• Related: 2mq0
• NMR Information: BMRB: 25010
• Descriptor: Myosin-binding protein C, cardiac-type (1 entity in total)
• Functional Keywords: cardiac myosin binding protein c, c3 domain, ig-like, hypertrophic cardiomyopathy, contractile protein
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 10856.34

Authors

Zhang, X.,De, S.,Mcintosh, L.P.,Paetzel, M. (deposition date: 2014-06-12, release date: 2014-07-30, Last modification date: 2023-06-14)

• Primary citation: Zhang, X.L.,De, S.,McIntosh, L.P.,Paetzel, M.; Structural Characterization of the C3 Domain of Cardiac Myosin Binding Protein C and Its Hypertrophic Cardiomyopathy-Related R502W Mutant.; Biochemistry, 53:5332-5342, 2014; PubMed: 25058872; DOI: 10.1021/bi500784g

Experimental method

SOLUTION NMR