2MQ3
NMR structure of the c3 domain of human cardiac myosin binding protein-c with a hypertrophic cardiomyopathy-related mutation R502W.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Myosin-binding protein C, cardiac-type | polymer | 95 | 10856.3 | 1 | UniProt (Q14896) Pfam (PF07679) In PDB | Homo sapiens (human) | Cardiac MyBP-C, C-protein, cardiac muscle isoform |
Sequence modifications
A: 453 - 543 (UniProt: Q14896)
| PDB | External Database | Details |
|---|---|---|
| Gly 449 | - | expression tag |
| Ser 450 | - | expression tag |
| His 451 | - | expression tag |
| Met 452 | - | expression tag |
| Trp 502 | Arg 502 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 10856.3 | |
| All* | Total formula weight | 10856.3 |
