8IBU
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![BU of 8ibu by Molmil](/molmil-images/mine/8ibu) | Cryo-EM structure of the erythromycin-bound motilin receptor-Gq protein complex | Descriptor: | ERYTHROMYCIN A, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | You, C, Jiang, Y, Xu, H.E, Xu, Y. | Deposit date: | 2023-02-10 | Release date: | 2023-04-12 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (3.51 Å) | Cite: | Structural basis for motilin and erythromycin recognition by motilin receptor. Sci Adv, 9, 2023
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8XTE
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![BU of 8xte by Molmil](/molmil-images/mine/8xte) | Crystal structure of methyltransferase MpaG' in complex with SAH and FDHMP | Descriptor: | 4-farnesyl-3,5-dihydroxy-6-methylphthalide, O-methyltransferase mpaG', S-ADENOSYL-L-HOMOCYSTEINE | Authors: | You, C, Pan, Y.J, Li, S.Y, Feng, Y.G. | Deposit date: | 2024-01-10 | Release date: | 2024-08-28 | Method: | X-RAY DIFFRACTION (1.99 Å) | Cite: | Structural basis for substrate flexibility of the O-methyltransferase MpaG' involved in mycophenolic acid biosynthesis. Protein Sci., 33, 2024
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8XTG
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![BU of 8xtg by Molmil](/molmil-images/mine/8xtg) | Crystal structure of methyltransferase MpaG' in complex with SAH and DMMPA | Descriptor: | O-desmethyl mycophenolic acid, O-methyltransferase mpaG', S-ADENOSYL-L-HOMOCYSTEINE | Authors: | You, C, Pan, Y.J, Li, S.Y, Feng, Y.G. | Deposit date: | 2024-01-10 | Release date: | 2024-08-28 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural basis for substrate flexibility of the O-methyltransferase MpaG' involved in mycophenolic acid biosynthesis. Protein Sci., 33, 2024
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8XTF
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![BU of 8xtf by Molmil](/molmil-images/mine/8xtf) | Crystal structure of methyltransferase MpaG' in complex with SAH and FDHMP-3C | Descriptor: | 4-farnesyl-3,5-dihydroxy-6-methylphthalide-3C, O-methyltransferase mpaG', S-ADENOSYL-L-HOMOCYSTEINE | Authors: | You, C, Pan, Y.J, Li, S.Y, Feng, Y.G. | Deposit date: | 2024-01-10 | Release date: | 2024-08-28 | Method: | X-RAY DIFFRACTION (2.13 Å) | Cite: | Structural basis for substrate flexibility of the O-methyltransferase MpaG' involved in mycophenolic acid biosynthesis. Protein Sci., 33, 2024
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7W57
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![BU of 7w57 by Molmil](/molmil-images/mine/7w57) | Cryo-EM structure of the neuromedin S-bound neuromedin U receptor 2-Gq protein complex | Descriptor: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(q) subunit alpha, ... | Authors: | You, C, Xu, H.E, Jiang, Y. | Deposit date: | 2021-11-29 | Release date: | 2022-04-20 | Last modified: | 2022-06-15 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Structural insights into the peptide selectivity and activation of human neuromedin U receptors. Nat Commun, 13, 2022
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7W56
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![BU of 7w56 by Molmil](/molmil-images/mine/7w56) | Cryo-EM structure of the neuromedin S-bound neuromedin U receptor 1-Gq protein complex | Descriptor: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(q) subunit alpha, ... | Authors: | You, C, Xu, H.E, Jiang, Y. | Deposit date: | 2021-11-29 | Release date: | 2022-04-20 | Last modified: | 2022-12-07 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Structural insights into the peptide selectivity and activation of human neuromedin U receptors. Nat Commun, 13, 2022
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7W55
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![BU of 7w55 by Molmil](/molmil-images/mine/7w55) | Cryo-EM structure of the neuromedin U-bound neuromedin U receptor 2-Gq protein complex | Descriptor: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(q) subunit alpha, ... | Authors: | You, C, Xu, H.E, Jiang, Y. | Deposit date: | 2021-11-29 | Release date: | 2022-04-20 | Last modified: | 2022-06-15 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Structural insights into the peptide selectivity and activation of human neuromedin U receptors. Nat Commun, 13, 2022
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7W53
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![BU of 7w53 by Molmil](/molmil-images/mine/7w53) | Cryo-EM structure of the neuromedin U-bound neuromedin U receptor 1-Gq protein complex | Descriptor: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(q) subunit alpha, ... | Authors: | You, C, Xu, H.E, Jiang, Y. | Deposit date: | 2021-11-29 | Release date: | 2022-04-20 | Last modified: | 2022-06-15 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Structural insights into the peptide selectivity and activation of human neuromedin U receptors. Nat Commun, 13, 2022
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8IBV
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![BU of 8ibv by Molmil](/molmil-images/mine/8ibv) | Cryo-EM structure of the motilin-bound motilin receptor-Gq protein complex | Descriptor: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(q) subunit alpha, ... | Authors: | Jiang, Y, Xu, H.E, You, C, Xu, Y. | Deposit date: | 2023-02-10 | Release date: | 2023-04-12 | Method: | ELECTRON MICROSCOPY (3.19 Å) | Cite: | Structural basis for motilin and erythromycin recognition by motilin receptor. Sci Adv, 9, 2023
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7DBL
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![BU of 7dbl by Molmil](/molmil-images/mine/7dbl) | Acyl-CoA hydrolase MpaH' mutant S139A in complex with MPA | Descriptor: | MYCOPHENOLIC ACID, acyl-CoA hydrolase MpaH' | Authors: | Li, S.Y, You, C. | Deposit date: | 2020-10-20 | Release date: | 2021-04-28 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.84 Å) | Cite: | Structural basis for substrate specificity of the peroxisomal acyl-CoA hydrolase MpaH' involved in mycophenolic acid biosynthesis. Febs J., 288, 2021
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7DBI
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![BU of 7dbi by Molmil](/molmil-images/mine/7dbi) | Crystal structure of the peroxisomal acyl-CoA hydrolase MpaH | Descriptor: | acyl-CoA hydrolase MpaH' | Authors: | Li, S.Y, You, C. | Deposit date: | 2020-10-20 | Release date: | 2021-04-28 | Last modified: | 2021-10-13 | Method: | X-RAY DIFFRACTION (1.99 Å) | Cite: | Structural basis for substrate specificity of the peroxisomal acyl-CoA hydrolase MpaH' involved in mycophenolic acid biosynthesis. Febs J., 288, 2021
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8X8L
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![BU of 8x8l by Molmil](/molmil-images/mine/8x8l) | Cryo-EM structure of the cortistatin 17-bound Somatostatin receptor 5-Gi protein complex | Descriptor: | Cortistatin, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | Xu, H.E, You, C, Zhao, L, Li, J. | Deposit date: | 2023-11-27 | Release date: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (2.7 Å) | Cite: | Cryo-EM structure of the cortistatin 17-bound Somatostatin receptor 5-Gi protein complex To Be Published
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8X8N
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![BU of 8x8n by Molmil](/molmil-images/mine/8x8n) | Cryo-EM structure of the octreotide-bound Somatostatin receptor 5-Gi protein complex | Descriptor: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha, ... | Authors: | Xu, H.E, You, C, Zhao, L, Li, J. | Deposit date: | 2023-11-27 | Release date: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Cryo-EM structure of the octreotide-bound Somatostatin receptor 5-Gi protein complex To Be Published
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7XHP
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![BU of 7xhp by Molmil](/molmil-images/mine/7xhp) | |
5Z9Z
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![BU of 5z9z by Molmil](/molmil-images/mine/5z9z) | The C-terminal RRM domain of Arabidopsis SMALL RNA DEGRADING NUCLEASE 1 (E329A/E330A/E332A) | Descriptor: | CITRATE ANION, Small RNA degrading nuclease 1 | Authors: | Chen, J, Liu, L, You, C, Gu, J, Ruan, W, Zhang, L, Cao, C, Gan, J, Huang, Y, Chen, X, Ma, J. | Deposit date: | 2018-02-05 | Release date: | 2018-06-27 | Last modified: | 2018-10-03 | Method: | X-RAY DIFFRACTION (2.049 Å) | Cite: | Structural and biochemical insights into small RNA 3' end trimming by Arabidopsis SDN1. Nat Commun, 9, 2018
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5YLY
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![BU of 5yly by Molmil](/molmil-images/mine/5yly) | |
5Z9X
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![BU of 5z9x by Molmil](/molmil-images/mine/5z9x) | Arabidopsis SMALL RNA DEGRADING NUCLEASE 1 in complex with an RNA substrate | Descriptor: | MAGNESIUM ION, RNA (5'-R(P*GP*CP*CP*CP*AP*UP*UP*AP*G)-3'), SULFATE ION, ... | Authors: | Chen, J, Liu, L, You, C, Gu, J, Ruan, W, Zhang, L, Gan, J, Cao, C, Huang, Y, Chen, X, Ma, J. | Deposit date: | 2018-02-05 | Release date: | 2018-06-27 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural and biochemical insights into small RNA 3' end trimming by Arabidopsis SDN1. Nat Commun, 9, 2018
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7XHL
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![BU of 7xhl by Molmil](/molmil-images/mine/7xhl) | Complex structure of a Glucose 6-Phosphate Dehydrogenase from Zymomonas mobilis | Descriptor: | BETA-NICOTINAMIDE RIBOSE MONOPHOSPHATE, Glucose 6-Phosphate Dehydrogenase | Authors: | Meng, D.D, Liu, M.X, Liu, W.D, You, C. | Deposit date: | 2022-04-08 | Release date: | 2023-04-12 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3.25 Å) | Cite: | Coenzyme Engineering of Glucose-6-phosphate Dehydrogenase on a Nicotinamide-Based Biomimic and Its Application as a Glucose Biosensor Acs Catalysis, 13, 2023
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7XTB
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![BU of 7xtb by Molmil](/molmil-images/mine/7xtb) | Serotonin 6 (5-HT6) receptor-Gs-Nb35 complex | Descriptor: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ... | Authors: | Huang, S, Xu, P, Shen, D.D, Simon, I.A, Mao, C, Tan, Y, Zhang, H, Harpsoe, K, Li, H, Zhang, Y, You, C, Yu, X, Jiang, Y, Zhang, Y, Gloriam, D.E, Xu, H.E. | Deposit date: | 2022-05-16 | Release date: | 2022-07-27 | Last modified: | 2022-08-03 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | GPCRs steer G i and G s selectivity via TM5-TM6 switches as revealed by structures of serotonin receptors. Mol.Cell, 82, 2022
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7XTA
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![BU of 7xta by Molmil](/molmil-images/mine/7xta) | Serotonin 4 (5-HT4) receptor-Gi-scFv16 complex | Descriptor: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... | Authors: | Huang, S, Xu, P, Shen, D.D, Simon, I.A, Mao, C, Tan, Y, Zhang, H, Harpsoe, K, Li, H, Zhang, Y, You, C, Yu, X, Jiang, Y, Zhang, Y, Gloriam, D.E, Xu, H.E. | Deposit date: | 2022-05-16 | Release date: | 2022-07-27 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | GPCRs steer G i and G s selectivity via TM5-TM6 switches as revealed by structures of serotonin receptors. Mol.Cell, 82, 2022
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7XTC
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![BU of 7xtc by Molmil](/molmil-images/mine/7xtc) | Serotonin 7 (5-HT7) receptor-Gs-Nb35 complex | Descriptor: | 3-(2-azanylethyl)-1H-indole-5-carboxamide, CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | Authors: | Huang, S, Xu, P, Shen, D.D, Simon, I.A, Mao, C, Tan, Y, Zhang, H, Harpsoe, K, Li, H, Zhang, Y, You, C, Yu, X, Jiang, Y, Zhang, Y, Gloriam, D.E, Xu, H.E. | Deposit date: | 2022-05-16 | Release date: | 2022-07-27 | Last modified: | 2022-08-03 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | GPCRs steer G i and G s selectivity via TM5-TM6 switches as revealed by structures of serotonin receptors. Mol.Cell, 82, 2022
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7XT9
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![BU of 7xt9 by Molmil](/molmil-images/mine/7xt9) | Serotonin 4 (5-HT4) receptor-Gs complex | Descriptor: | CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | Huang, S, Xu, P, Shen, D.D, Simon, I.A, Mao, C, Tan, Y, Zhang, H, Harpsoe, K, Li, H, Zhang, Y, You, C, Yu, X, Jiang, Y, Zhang, Y, Gloriam, D.E, Xu, H.E. | Deposit date: | 2022-05-16 | Release date: | 2022-07-27 | Last modified: | 2022-08-03 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | GPCRs steer G i and G s selectivity via TM5-TM6 switches as revealed by structures of serotonin receptors. Mol.Cell, 82, 2022
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7XT8
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![BU of 7xt8 by Molmil](/molmil-images/mine/7xt8) | Serotonin 4 (5-HT4) receptor-Gs-Nb35 complex | Descriptor: | CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | Huang, S, Xu, P, Shen, D.D, Simon, I.A, Mao, C, Tan, Y, Zhang, H, Harpsoe, K, Li, H, Zhang, Y, You, C, Yu, X, Jiang, Y, Zhang, Y, Gloriam, D.E, Xu, H.E. | Deposit date: | 2022-05-16 | Release date: | 2022-07-27 | Last modified: | 2022-08-03 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | GPCRs steer G i and G s selectivity via TM5-TM6 switches as revealed by structures of serotonin receptors. Mol.Cell, 82, 2022
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7WKD
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![BU of 7wkd by Molmil](/molmil-images/mine/7wkd) | TRH-TRHR G protein complex | Descriptor: | Gq, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | Xu, Y, Cai, H, You, C, He, X, Yuan, Q, Jiang, H, Cheng, X, Jiang, Y, Xu, H.E. | Deposit date: | 2022-01-09 | Release date: | 2022-06-15 | Last modified: | 2022-09-14 | Method: | ELECTRON MICROSCOPY (3.01 Å) | Cite: | Structural insights into ligand binding and activation of the human thyrotropin-releasing hormone receptor. Cell Res., 32, 2022
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1TVM
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![BU of 1tvm by Molmil](/molmil-images/mine/1tvm) | NMR structure of enzyme GatB of the galactitol-specific phosphoenolpyruvate-dependent phosphotransferase system | Descriptor: | PTS system, galactitol-specific IIB component | Authors: | Volpon, L, Young, C.R, Lim, N.S, Iannuzzi, P, Cygler, M, Gehring, K, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI) | Deposit date: | 2004-06-29 | Release date: | 2005-09-06 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | NMR structure of the enzyme GatB of the galactitol-specific phosphoenolpyruvate-dependent phosphotransferase system and its interaction with GatA. Protein Sci., 15, 2006
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