7WKD

TRH-TRHR G protein complex

Summary for 7WKD

• Entry DOI: 10.2210/pdb7wkd/pdb
• EMDB information: 32565
• Descriptor: Gq, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, scFV16, ... (6 entities in total)
• Functional Keywords: trh, trhr, activation, thyrotropin-releasing hormone, hormone
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 6
• Total formula weight: 160090.26

Authors

Xu, Y.,Cai, H.,You, C.,He, X.,Yuan, Q.,Jiang, H.,Cheng, X.,Jiang, Y.,Xu, H.E. (deposition date: 2022-01-09, release date: 2022-06-15, Last modification date: 2022-09-14)

• Primary citation: Xu, Y.,Cai, H.,You, C.,He, X.,Yuan, Q.,Jiang, H.,Cheng, X.,Jiang, Y.,Xu, H.E.; Structural insights into ligand binding and activation of the human thyrotropin-releasing hormone receptor.; Cell Res., 32:855-857, 2022; PubMed: 35365755; DOI: 10.1038/s41422-022-00641-x

Experimental method

ELECTRON MICROSCOPY (3.01 Å)