7DBL

Acyl-CoA hydrolase MpaH' mutant S139A in complex with MPA

Summary for 7DBL

• Entry DOI: 10.2210/pdb7dbl/pdb
• Descriptor: acyl-CoA hydrolase MpaH', MYCOPHENOLIC ACID (3 entities in total)
• Functional Keywords: peroxisomal acyl-coa hydrolase, mpah', mpa biosynthesis, hydrolase
• Biological source: Penicillium brevicompactum
• Total number of polymer chains: 4
• Total formula weight: 198074.43

Authors

Li, S.Y.,You, C. (deposition date: 2020-10-20, release date: 2021-04-28, Last modification date: 2023-11-29)

• Primary citation: You, C.,Li, F.,Zhang, X.,Ma, L.,Zhang, Y.Z.,Zhang, W.,Li, S.; Structural basis for substrate specificity of the peroxisomal acyl-CoA hydrolase MpaH' involved in mycophenolic acid biosynthesis.; Febs J., 288:5768-5780, 2021; PubMed: 33843134; DOI: 10.1111/febs.15874

Experimental method

X-RAY DIFFRACTION (1.84 Å)