6IG2
 
 | | Structure of mitochondrial CDP-DAG synthase Tam41 complexed with CTP, delta 74, F240A | | 分子名称: | CYTIDINE-5'-TRIPHOSPHATE, Phosphatidate cytidylyltransferase, mitochondrial | | 著者 | Jiao, H.Z, Yin, Y, Liu, Z.F. | | 登録日 | 2018-09-23 | | 公開日 | 2019-07-10 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.882 Å) | | 主引用文献 | Structures of the Mitochondrial CDP-DAG Synthase Tam41 Suggest a Potential Lipid Substrate Pathway from Membrane to the Active Site.
Structure, 27, 2019
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6INE
 | | Crystal Structure of human ASH1L-MRG15 complex | | 分子名称: | GLYCEROL, Histone-lysine N-methyltransferase ASH1L, Mortality factor 4-like protein 1, ... | | 著者 | Hou, P, Huang, C, Liu, C.P, Yu, T, Yin, Y, Zhu, B, Xu, R.M. | | 登録日 | 2018-10-25 | | 公開日 | 2019-03-20 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structural Insights into Stimulation of Ash1L's H3K36 Methyltransferase Activity through Mrg15 Binding.
Structure, 27, 2019
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6IG4
 | | Structure of mitochondrial CDP-DAG synthase Tam41, delta 74 | | 分子名称: | PLATINUM (II) ION, Phosphatidate cytidylyltransferase, mitochondrial, ... | | 著者 | Jiao, H.Z, Yin, Y, Liu, Z.F. | | 登録日 | 2018-09-23 | | 公開日 | 2019-07-10 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (2.261 Å) | | 主引用文献 | Structures of the Mitochondrial CDP-DAG Synthase Tam41 Suggest a Potential Lipid Substrate Pathway from Membrane to the Active Site.
Structure, 27, 2019
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8SWK
 | | Cryo-EM structure of NLRP3 closed hexamer | | 分子名称: | 1-[4-(2-oxidanylpropan-2-yl)furan-2-yl]sulfonyl-3-(1,2,3,5-tetrahydro-s-indacen-4-yl)urea, ADENOSINE-5'-TRIPHOSPHATE, NACHT, ... | | 著者 | Yu, X, Matico, R.E, Miller, R, Schoubroeck, B.V, Grauwen, K, Suarez, J, Pietrak, B, Haloi, N, Yin, Y, Tresadern, G.J, Perez-Benito, L, Lindahl, E, Bottelbergs, A, Oehlrich, D, Opdenbosch, N.V, Sharma, S. | | 登録日 | 2023-05-18 | | 公開日 | 2024-02-14 | | 実験手法 | ELECTRON MICROSCOPY (4.32 Å) | | 主引用文献 | Cryo-EM structures of NLRP3 reveal its self-activation mechanism
Nat Commun, 2024
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8SWF
 | | Cryo-EM structure of NLRP3 open octamer | | 分子名称: | NACHT, LRR and PYD domains-containing protein 3 | | 著者 | Yu, X, Matico, R.E, Miller, R, Schoubroeck, B.V, Grauwen, K, Suarez, J, Pietrak, B, Haloi, N, Yin, Y, Tresadern, G.J, Perez-Benito, L, Lindahl, E, Bottelbergs, A, Oehlrich, D, Opdenbosch, N.V, Sharma, S. | | 登録日 | 2023-05-18 | | 公開日 | 2024-02-14 | | 実験手法 | ELECTRON MICROSCOPY (3.39 Å) | | 主引用文献 | Cryo-EM structures of NLRP3 reveal its self-activation mechanism
Nat Commun, 2024
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8SXN
 | | Structure of NLRP3 and NEK7 complex | | 分子名称: | 1-[4-(2-oxidanylpropan-2-yl)furan-2-yl]sulfonyl-3-(1,2,3,5-tetrahydro-s-indacen-4-yl)urea, ADENOSINE-5'-TRIPHOSPHATE, NACHT, ... | | 著者 | Yu, X, Matico, R.E, Miller, R, Schoubroeck, B.V, Grauwen, K, Suarez, J, Pietrak, B, Haloi, N, Yin, Y, Tresadern, G.J, Perez-Benito, L, Lindahl, E, Bottelbergs, A, Oehlrich, D, Opdenbosch, N.V, Sharma, S. | | 登録日 | 2023-05-22 | | 公開日 | 2024-02-14 | | 実験手法 | ELECTRON MICROSCOPY (4.04 Å) | | 主引用文献 | Cryo-EM structures of NLRP3 reveal its self-activation mechanism
Nat Commun, 2024
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7R6V
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8BZM
 | | FOXK1-ELF1-heterodimer bound to DNA | | 分子名称: | DNA, ETS-related transcription factor Elf-1, Forkhead box protein K1, ... | | 著者 | Morgunova, E, Popov, A, Yin, Y, Taipale, J. | | 登録日 | 2022-12-15 | | 公開日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.69 Å) | | 主引用文献 | FOXK1-ELF1_heterodimer bound to DNA
To Be Published
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8IJ1
 | | Protomer 1 and 2 of the asymmetry trimer of the Cul2-Rbx1-EloBC-FEM1B ubiquitin ligase complex | | 分子名称: | Cullin-2, E3 ubiquitin-protein ligase RBX1, Elongin-B, ... | | 著者 | Dai, Z, Liang, L, Yin, Y.X. | | 登録日 | 2023-02-24 | | 公開日 | 2024-02-28 | | 最終更新日 | 2024-04-03 | | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | | 主引用文献 | Structural insights into the ubiquitylation strategy of the oligomeric CRL2 FEM1B E3 ubiquitin ligase.
Embo J., 43, 2024
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7R6T
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7Z5I
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7Z5K
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8PE9
 | | Complex between DDR1 DS-like domain and PRTH-101 Fab | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | | 著者 | Liu, J, Chiang, H, Xiong, W, Laurent, V, Griffiths, S.C, Duelfer, J, Deng, H, Sun, X, Yin, Y.W, Li, W, Audoly, L.P, An, Z, Schuerpf, T, Li, R, Zhang, N. | | 登録日 | 2023-06-13 | | 公開日 | 2023-06-28 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (3.152 Å) | | 主引用文献 | A highly selective humanized DDR1 mAb reverses immune exclusion by disrupting collagen fiber alignment in breast cancer.
J Immunother Cancer, 11, 2023
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8BYX
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1O8T
 | | Global Structure and Dynamics of Human Apolipoprotein CII in Complex with Micelles: Evidence for increased mobility of the helix involved in the activation of lipoprotein lipase | | 分子名称: | APOLIPOPROTEIN C-II | | 著者 | Zdunek, J, Martinez, G.V, Schleucher, J, Lycksell, P.O, Yin, Y, Nilsson, S, Shen, Y, Olivecrona, G, Wijmenga, S. | | 登録日 | 2002-11-29 | | 公開日 | 2003-02-27 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Global Structure and Dynamics of Human Apolipoprotein Cii in Complex with Micelles: Evidence for Increased Mobility of the Helix Involved in the Activation of Lipoprotein Lipase
Biochemistry, 42, 2003
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8D42
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8D37
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8D3R
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8D33
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8EW6
 | | Anti-human CD8 VHH complex with CD8 alpha | | 分子名称: | Anti-CD8 alpha VHH, T-cell surface glycoprotein CD8 alpha chain | | 著者 | Kiefer, J.R, Williams, S, Davies, C.W, Koerber, J.T, Sriraman, S.K, Yin, Y.P. | | 登録日 | 2022-10-21 | | 公開日 | 2022-11-23 | | 最終更新日 | 2023-02-01 | | 実験手法 | X-RAY DIFFRACTION (1.904 Å) | | 主引用文献 | Development of an 18 F-labeled anti-human CD8 VHH for same-day immunoPET imaging.
Eur J Nucl Med Mol Imaging, 50, 2023
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5TDH
 | | The crystal structure of the dominant negative mutant G protein alpha(i)-1-beta-1-gamma-2 G203A/A326S | | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | 著者 | Liu, P, Jia, M.-Z, Zhou, X.E, de Waal, P.W, Dickson, B.M, Liu, B, Hou, L, Yin, Y.-T, Kang, Y.-Y, Shi, Y, Melcher, K, Xu, H.E, Jiang, Y. | | 登録日 | 2016-09-19 | | 公開日 | 2016-11-09 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | The structural basis of the dominant negative phenotype of the G alpha i1 beta 1 gamma 2 G203A/A326S heterotrimer
Acta Pharmacol.Sin., 37, 2016
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3C8O
 | | The Crystal Structure of RraA from PAO1 | | 分子名称: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Regulator of ribonuclease activity A, ... | | 著者 | Luo, M, Niu, S, Yin, Y, Huang, A, Wang, D. | | 登録日 | 2008-02-12 | | 公開日 | 2009-02-17 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | The Crystal Structure of RraA from PAO1
To be published
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3IKM
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3IKL
 | | Crystal structure of Pol gB delta-I4. | | 分子名称: | DNA polymerase subunit gamma-2, mitochondrial | | 著者 | Lee, Y.S, Kennedy, W.D, Yin, Y.W. | | 登録日 | 2009-08-06 | | 公開日 | 2010-08-25 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Structural insight into processive human mitochondrial DNA synthesis and disease-related polymerase mutations.
Cell(Cambridge,Mass.), 139, 2009
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6CMO
 | | Rhodopsin-Gi complex | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab Heavy chain, Fab light chain, ... | | 著者 | Kang, Y, Kuybeda, O, de Waal, P.W, Mukherjee, S, Van Eps, N, Dutka, P, Zhou, X.E, Bartesaghi, A, Erramilli, S, Morizumi, T, Gu, X, Yin, Y, Liu, P, Jiang, Y, Meng, X, Zhao, G, Melcher, K, Earnst, O.P, Kossiakoff, A.A, Subramaniam, S, Xu, H.E. | | 登録日 | 2018-03-05 | | 公開日 | 2018-06-20 | | 最終更新日 | 2020-07-29 | | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | | 主引用文献 | Cryo-EM structure of human rhodopsin bound to an inhibitory G protein.
Nature, 558, 2018
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