Structure of mitochondrial CDP-DAG synthase Tam41 complexed with CTP, delta 74, F240A

Summary for 6IG2

DescriptorPhosphatidate cytidylyltransferase, mitochondrial, CYTIDINE-5'-TRIPHOSPHATE (3 entities in total)
Functional Keywordsmitochondrial inner membrane, cdp-diacylglycerol synthase, ntase fold, transferase
Biological sourceSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Total number of polymer chains4
Total molecular weight143910.03
Jiao, H.Z.,Yin, Y.,Liu, Z.F. (deposition date: 2018-09-23, release date: 2019-07-10, Last modification date: 2019-08-21)
Primary citation
Jiao, H.,Yin, Y.,Liu, Z.
Structures of the Mitochondrial CDP-DAG Synthase Tam41 Suggest a Potential Lipid Substrate Pathway from Membrane to the Active Site.
Structure, 27:1258-, 2019
PubMed: 31178220 (PDB entries with the same primary citation)
DOI: 10.1016/j.str.2019.04.017
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.2594 0.2% 2.2% 1.7%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution