6IG2

Structure of mitochondrial CDP-DAG synthase Tam41 complexed with CTP, delta 74, F240A

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Phosphatidate cytidylyltransferase, mitochondrial	polymer	313	35856.7	4	UniProt (O74339) Pfam (PF09139)	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	Tam41, CDP-diacylglycerol synthase,CDP-DAG synthase,Mitochondrial translocator assembly and maintenance protein 41 homolog
2	E (D)	CYTIDINE-5'-TRIPHOSPHATE	non-polymer		483.2	1	Chemie (CTP)
3	F, G, H, I (A, B, C, D)	water	water		18.0	216	Chemie (HOH)

Sequence modifications

A, B, C, D: 28 - 319 (UniProt: O74339)

PDB	External Database	Details
Met 7	-	expression tag
Gly 8	-	expression tag
Ser 9	-	expression tag
Ser 10	-	expression tag
His 11	-	expression tag
His 12	-	expression tag
His 13	-	expression tag
His 14	-	expression tag
His 15	-	expression tag
His 16	-	expression tag
Ser 17	-	expression tag
Ser 18	-	expression tag
Gly 19	-	expression tag
Leu 20	-	expression tag
Val 21	-	expression tag
Pro 22	-	expression tag
Arg 23	-	expression tag
Gly 24	-	expression tag
Ser 25	-	expression tag
His 26	-	expression tag
Met 27	-	expression tag
Ala 240	Phe 240	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	143426.9
Non-Polymers*	Number of molecules	1
	Total formula weight	483.2
All*	Total formula weight	143910.0

*Water molecules are not included.