8D9X
| Cryo-EM structure of human DELE1 in oligomeric form | Descriptor: | Maltodextrin-binding protein,DAP3-binding cell death enhancer 1 short form | Authors: | Yang, J, Lander, G.C. | Deposit date: | 2022-06-11 | Release date: | 2023-06-14 | Last modified: | 2023-09-20 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | DELE1 oligomerization promotes integrated stress response activation. Nat.Struct.Mol.Biol., 30, 2023
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7N1R
| A novel and unique ATP hydrolysis to AMP by a human Hsp70 BiP | Descriptor: | ADENOSINE MONOPHOSPHATE, DI(HYDROXYETHYL)ETHER, Endoplasmic reticulum chaperone BiP, ... | Authors: | Yang, J, Musayev, F, Liu, Q. | Deposit date: | 2021-05-28 | Release date: | 2022-01-12 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.03 Å) | Cite: | A novel and unique ATP hydrolysis to AMP by a human Hsp70 Binding immunoglobin protein (BiP). Protein Sci., 31, 2022
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8ZKC
| iron-sulfur cluster transfer protein ApbC | Descriptor: | GLYCEROL, Iron-sulfur cluster carrier protein, MAGNESIUM ION | Authors: | Yang, J, Liu, L. | Deposit date: | 2024-05-16 | Release date: | 2024-06-12 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | Crystal structure of the iron-sulfur cluster transfer protein ApbC from Escherichia coli. Biochem.Biophys.Res.Commun., 722, 2024
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8J0P
| Chitin binding SusD-like protein AqSusD from a marine Bacteroidetes | Descriptor: | Chitin binding SusD-like protein | Authors: | Yang, J. | Deposit date: | 2023-04-11 | Release date: | 2023-11-01 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural insights of a SusD-like protein in marine Bacteroidetes bacteria reveal the molecular basis for chitin recognition and acquisition. Febs J., 291, 2024
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4A2N
| Crystal Structure of Ma-ICMT | Descriptor: | CARDIOLIPIN, ISOPRENYLCYSTEINE CARBOXYL METHYLTRANSFERASE, PALMITIC ACID, ... | Authors: | Yang, J, Kulkarni, K, Manolaridis, I, Zhang, Z, Dodd, R.B, Mas-Droux, C, Barford, D. | Deposit date: | 2011-09-27 | Release date: | 2012-01-11 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (3.4 Å) | Cite: | Mechanism of Isoprenylcysteine Carboxyl Methylation from the Crystal Structure of the Integral Membrane Methyltransferase Icmt. Mol.Cell, 44, 2011
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6PZP
| Crystal structure of caspase-1 in complex with VX-765 | Descriptor: | Caspase-1, N-(4-amino-3-chlorobenzene-1-carbonyl)-3-methyl-L-valyl-N-[(2S)-1-carboxy-3-oxopropan-2-yl]-L-prolinamide | Authors: | Yang, J, Liu, Z, Xiao, T.S. | Deposit date: | 2019-08-01 | Release date: | 2020-08-05 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.94 Å) | Cite: | Crystal structure of caspase-1 in complex with VX-765 To Be Published
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8JXZ
| Chitin binding SusD-like protein AqSusD in complex with (GlcNAc)3 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, SusD-like protein AqSusD | Authors: | Yang, J. | Deposit date: | 2023-07-01 | Release date: | 2023-11-01 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural insights of a SusD-like protein in marine Bacteroidetes bacteria reveal the molecular basis for chitin recognition and acquisition. Febs J., 291, 2024
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1ASH
| THE STRUCTURE OF ASCARIS HEMOGLOBIN DOMAIN I AT 2.2 ANGSTROMS RESOLUTION: MOLECULAR FEATURES OF OXYGEN AVIDITY | Descriptor: | HEMOGLOBIN (OXY), OXYGEN MOLECULE, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Yang, J, Mathews, F.S, Kloek, A.P, Goldberg, D.E. | Deposit date: | 1995-01-06 | Release date: | 1995-02-27 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | The structure of Ascaris hemoglobin domain I at 2.2 A resolution: molecular features of oxygen avidity. Proc.Natl.Acad.Sci.USA, 92, 1995
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2RMP
| RMP-pepstatin A complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, MUCOROPEPSIN, PEPSTATIN, ... | Authors: | Yang, J, Quail, J.W. | Deposit date: | 1997-05-30 | Release date: | 1997-09-17 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structure of the Rhizomucor miehei aspartic proteinase complexed with the inhibitor pepstatin A at 2.7 A resolution. Acta Crystallogr.,Sect.D, 55, 1999
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2WMN
| Structure of the complex between DOCK9 and Cdc42-GDP. | Descriptor: | CELL DIVISION CONTROL PROTEIN 42 HOMOLOG, DEDICATOR OF CYTOKINESIS PROTEIN 9, GUANOSINE-5'-DIPHOSPHATE | Authors: | Yang, J, Roe, S.M, Barford, D. | Deposit date: | 2009-07-02 | Release date: | 2009-09-22 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.391 Å) | Cite: | Activation of Rho Gtpases by Dock Exchange Factors is Mediated by a Nucleotide Sensor. Science, 325, 2009
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2WMO
| Structure of the complex between DOCK9 and Cdc42. | Descriptor: | CELL DIVISION CONTROL PROTEIN 42 HOMOLOG, DEDICATOR OF CYTOKINESIS PROTEIN 9, GUANOSINE-5'-TRIPHOSPHATE, ... | Authors: | Yang, J, Roe, S.M, Barford, D. | Deposit date: | 2009-07-02 | Release date: | 2009-09-22 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Activation of Rho Gtpases by Dock Exchange Factors is Mediated by a Nucleotide Sensor. Science, 325, 2009
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2WM9
| Structure of the complex between DOCK9 and Cdc42. | Descriptor: | CELL DIVISION CONTROL PROTEIN 42 HOMOLOG, DEDICATOR OF CYTOKINESIS PROTEIN 9, GLYCEROL | Authors: | Yang, J, Roe, S.M, Barford, D. | Deposit date: | 2009-06-30 | Release date: | 2009-09-22 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Activation of Rho Gtpases by Dock Exchange Factors is Mediated by a Nucleotide Sensor. Science, 325, 2009
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8JJB
| Crystal structure of T2R-TTL-Y61 complex | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, CHLORIDE ION, ... | Authors: | Yang, J. | Deposit date: | 2023-05-30 | Release date: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.68 Å) | Cite: | Structure-based design and synthesis of BML284 derivatives: A novel class of colchicine-site noncovalent tubulin degradation agents. Eur.J.Med.Chem., 268, 2024
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8JJC
| Tubulin-Y62 | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 4-(6,7-dimethoxy-3,4-dihydro-1~{H}-isoquinolin-2-yl)-6-(3-methoxyphenyl)pyrimidin-2-amine, CALCIUM ION, ... | Authors: | Yang, J. | Deposit date: | 2023-05-30 | Release date: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.76 Å) | Cite: | Structure-based design and synthesis of BML284 derivatives: A novel class of colchicine-site noncovalent tubulin degradation agents. Eur.J.Med.Chem., 268, 2024
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8K2P
| Crystal structure of CtGST-F76A | Descriptor: | Glutathione S-transferase | Authors: | Yang, J, Xiao, J.Y, Lei, X.G. | Deposit date: | 2023-07-13 | Release date: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Enzymatic Degradation of Deoxynivalenol with the Engineered Detoxification Enzyme Fhb7. Jacs Au, 4, 2024
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8K2O
| Crystal structure of Fhb7-M10 | Descriptor: | Fhb7-M10 | Authors: | Yang, J, Lei, X.G, Xiao, J.Y. | Deposit date: | 2023-07-13 | Release date: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.01 Å) | Cite: | Enzymatic Degradation of Deoxynivalenol with the Engineered Detoxification Enzyme Fhb7. Jacs Au, 4, 2024
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8JDH
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8JDI
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8H5T
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8H5U
| Crystal structure of SARS-CoV-2 spike receptor-binding domain in complex with neutralizing nanobody Nb-021 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Nanobody Nb-021, ... | Authors: | Yang, J, Lin, S, Lu, G.W. | Deposit date: | 2022-10-13 | Release date: | 2023-10-18 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.401 Å) | Cite: | Development of a bispecific nanobody conjugate broadly neutralizes diverse SARS-CoV-2 variants and structural basis for its broad neutralization. Plos Pathog., 19, 2023
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1H6G
| alpha-catenin M-domain | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, ALPHA-1 CATENIN, CALCIUM ION, ... | Authors: | Yang, J, Dokurno, P, Tonks, N.K, Barford, D. | Deposit date: | 2001-06-14 | Release date: | 2001-08-07 | Last modified: | 2016-02-10 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal Structure of the M-Fragment of Alpha-Catenin: Implications for Modulation of Cell Adhesion. Embo J., 20, 2001
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8KFA
| Cryo-EM structure of HSV-1 gB with D48 Fab complex | Descriptor: | D48 heavy chain, D48 light chain, Envelope glycoprotein B | Authors: | Yang, J, Sun, C, Fang, X, Zeng, M, Liu, Z. | Deposit date: | 2023-08-15 | Release date: | 2024-01-03 | Method: | ELECTRON MICROSCOPY (3.04 Å) | Cite: | The structure of HSV-1 gB bound to a potent neutralizing antibody reveals a conservative antigenic domain across herpesviruses hlife, 2023
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7YP0
| Crystal structure of CtGST | Descriptor: | Glutathione S-transferase | Authors: | Yang, J, Fan, J.P, Lei, X.G. | Deposit date: | 2022-08-02 | Release date: | 2024-02-07 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Enzymatic Degradation of Deoxynivalenol with the Engineered Detoxification Enzyme Fhb7. Jacs Au, 4, 2024
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7YOC
| Crystal structure of Fhb7 | Descriptor: | Fhb7 | Authors: | Yang, J, Liang, K, Xiao, J.Y, Lei, X.G. | Deposit date: | 2022-08-01 | Release date: | 2024-02-07 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.41 Å) | Cite: | Enzymatic Degradation of Deoxynivalenol with the Engineered Detoxification Enzyme Fhb7. Jacs Au, 4, 2024
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8IL3
| Cryo-EM structure of CD38 in complex with FTL004 | Descriptor: | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1, Heavy chain, Light chain | Authors: | Yang, J, Wang, Y, Zhang, G. | Deposit date: | 2023-03-01 | Release date: | 2023-03-29 | Method: | ELECTRON MICROSCOPY (3.86 Å) | Cite: | FTL004, an anti-CD38 mAb with negligible RBC binding and enhanced pro-apoptotic activity, is a novel candidate for treatments of multiple myeloma and non-Hodgkin lymphoma. J Hematol Oncol, 15, 2022
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