8D9X
Cryo-EM structure of human DELE1 in oligomeric form
Summary for 8D9X
Entry DOI | 10.2210/pdb8d9x/pdb |
EMDB information | 27269 |
Descriptor | Maltodextrin-binding protein,DAP3-binding cell death enhancer 1 short form (1 entity in total) |
Functional Keywords | oligomer, mitochondria, integrated stress response, kinase, tetratricopeptide repeat, protein binding |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 8 |
Total formula weight | 586750.69 |
Authors | Yang, J.,Lander, G.C. (deposition date: 2022-06-11, release date: 2023-06-14, Last modification date: 2023-09-20) |
Primary citation | Yang, J.,Baron, K.R.,Pride, D.E.,Schneemann, A.,Guo, X.,Chen, W.,Song, A.S.,Aviles, G.,Kampmann, M.,Luke Wiseman, R.,Lander, G.C. DELE1 oligomerization promotes integrated stress response activation. Nat.Struct.Mol.Biol., 30:1295-1302, 2023 Cited by PubMed: 37550454DOI: 10.1038/s41594-023-01061-0 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.8 Å) |
Structure validation
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