8D9X

Cryo-EM structure of human DELE1 in oligomeric form

Summary for 8D9X

• Entry DOI: 10.2210/pdb8d9x/pdb
• EMDB information: 27269
• Descriptor: Maltodextrin-binding protein,DAP3-binding cell death enhancer 1 short form (1 entity in total)
• Functional Keywords: oligomer, mitochondria, integrated stress response, kinase, tetratricopeptide repeat, protein binding
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 8
• Total formula weight: 586750.69

Authors

Yang, J.,Lander, G.C. (deposition date: 2022-06-11, release date: 2023-06-14, Last modification date: 2023-09-20)

• Primary citation: Yang, J.,Baron, K.R.,Pride, D.E.,Schneemann, A.,Guo, X.,Chen, W.,Song, A.S.,Aviles, G.,Kampmann, M.,Luke Wiseman, R.,Lander, G.C.; DELE1 oligomerization promotes integrated stress response activation.; Nat.Struct.Mol.Biol., 30:1295-1302, 2023; PubMed: 37550454; DOI: 10.1038/s41594-023-01061-0

Experimental method

ELECTRON MICROSCOPY (3.8 Å)