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PDB: 473 件
1F9Q
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CRYSTAL STRUCTURE OF PLATELET FACTOR 4
分子名称: PLATELET FACTOR 4
著者Yang, J, Doyle, M, Faulk, T, Visentin, G, Aster, R, Edwards, B.
登録日2000-07-11
公開日2003-08-26
最終更新日2017-10-04
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure Comparison of Two Platelet Factor 4 Mutants with the Wild-Type Reveals the Epitopes for the Heparin-Induced Thrombocytopenia Antibodies
To be Published
1F9P
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BU of 1f9p by Molmil
CRYSTAL STRUCTURE OF CONNECTIVE TISSUE ACTIVATING PEPTIDE-III(CTAP-III) COMPLEXED WITH POLYVINYLSULFONIC ACID
分子名称: CONNECTIVE TISSUE ACTIVATING PEPTIDE-III, ETHANESULFONIC ACID
著者Yang, J, Faulk, T, Aster, R, Visentin, G, Edwards, B, Castor, C.
登録日2000-07-11
公開日2003-08-26
最終更新日2017-10-04
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献Structure of the CXC Chemokine, Connective Tissue Activating Peptide-III, Complexed with the Heparin Analogue, Polyvinylsulfonic Acid
To be Published
8W78
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BU of 8w78 by Molmil
Structure of Drosophila melanogaster L-2-hydroxyglutarate dehydrogenase in complex with FAD and 2-oxoglutarate
分子名称: 2-OXOGLUTARIC ACID, DODECYL-BETA-D-MALTOSIDE, FI05204p, ...
著者Yang, J, Chen, X, Jin, S, Ding, J.
登録日2023-08-30
公開日2023-11-29
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.81 Å)
主引用文献Structure and biochemical characterization of l-2-hydroxyglutarate dehydrogenase and its role in the pathogenesis of l-2-hydroxyglutaric aciduria.
J.Biol.Chem., 300, 2023
8W75
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Structure of Drosophila melanogaster L-2-hydroxyglutarate dehydrogenase
分子名称: DODECYL-BETA-D-MALTOSIDE, FI05204p, FLAVIN-ADENINE DINUCLEOTIDE
著者Yang, J, Chen, X, Jin, S, Ding, J.
登録日2023-08-30
公開日2023-11-29
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Structure and biochemical characterization of l-2-hydroxyglutarate dehydrogenase and its role in the pathogenesis of l-2-hydroxyglutaric aciduria.
J.Biol.Chem., 300, 2023
8W7F
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BU of 8w7f by Molmil
Structure of Drosophila melanogaster L-2-hydroxyglutarate dehydrogenase bound with FAD and a sulfate ion
分子名称: DODECYL-BETA-D-MALTOSIDE, FI05204p, FLAVIN-ADENINE DINUCLEOTIDE, ...
著者Yang, J, Chen, X, Jin, S, Ding, J.
登録日2023-08-30
公開日2023-11-29
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.299 Å)
主引用文献Structure and biochemical characterization of l-2-hydroxyglutarate dehydrogenase and its role in the pathogenesis of l-2-hydroxyglutaric aciduria.
J.Biol.Chem., 300, 2023
5HM2
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BU of 5hm2 by Molmil
Crystal structure of the 3C protease from South African Territories type 2 foot-and-mouth disease virus
分子名称: 3C proteinase
著者Yang, J, Leen, E.N, Curry, S.
登録日2016-01-15
公開日2016-03-02
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Crystal structure of the 3C protease from Southern African Territories type 2 foot-and-mouth disease virus.
Peerj, 4, 2016
4A2N
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BU of 4a2n by Molmil
Crystal Structure of Ma-ICMT
分子名称: CARDIOLIPIN, ISOPRENYLCYSTEINE CARBOXYL METHYLTRANSFERASE, PALMITIC ACID, ...
著者Yang, J, Kulkarni, K, Manolaridis, I, Zhang, Z, Dodd, R.B, Mas-Droux, C, Barford, D.
登録日2011-09-27
公開日2012-01-11
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Mechanism of Isoprenylcysteine Carboxyl Methylation from the Crystal Structure of the Integral Membrane Methyltransferase Icmt.
Mol.Cell, 44, 2011
1NFQ
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BU of 1nfq by Molmil
Rv2002 gene product from Mycobacterium tuberculosis
分子名称: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, Androsterone, Putative oxidoreductase Rv2002
著者Yang, J.K, Park, M.S, Waldo, G.S, Suh, S.W, TB Structural Genomics Consortium (TBSGC)
登録日2002-12-15
公開日2002-12-30
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Directed evolution approach to a structural genomics project: Rv2002 from Mycobacterium tuberculosis
Proc.Natl.Acad.Sci.USA, 100, 2003
1NFR
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Rv2002 gene product from Mycobacterium tuberculosis
分子名称: NICOTINAMIDE-ADENINE-DINUCLEOTIDE, Putative oxidoreductase Rv2002
著者Yang, J.K, Park, M.S, Waldo, G.S, Suh, S.W, TB Structural Genomics Consortium (TBSGC)
登録日2002-12-16
公開日2002-12-30
最終更新日2021-11-10
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Directed evolution approach to a structural genomics project: Rv2002 from Mycobacterium tuberculosis
Proc.Natl.Acad.Sci.USA, 100, 2003
8XHO
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BU of 8xho by Molmil
Deep sea bacterial PET plastic hydrolase MtCut with mutation S178C
分子名称: CALCIUM ION, PET plastic hydrolase
著者Yang, J.
登録日2023-12-18
公開日2024-04-03
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Deep sea bacterial PET plastic hydrolase MtCut with mutation S178C
To Be Published
8XBD
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BU of 8xbd by Molmil
GH18 family chitinase from cold seep metagenome
分子名称: GH18 chitinase-like superfamily protein
著者Yang, J.
登録日2023-12-06
公開日2023-12-27
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献GH18 family chitinase from cold seep metagenome
To Be Published
3QAM
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BU of 3qam by Molmil
Crystal Structure of Glu208Ala mutant of catalytic subunit of cAMP-dependent protein kinase
分子名称: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Protein kinase inhibitor, ...
著者Yang, J, Wu, J, Steichen, J, Taylor, S.S.
登録日2011-01-11
公開日2011-12-07
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献A conserved Glu-Arg salt bridge connects coevolved motifs that define the eukaryotic protein kinase fold.
J.Mol.Biol., 415, 2012
1RXT
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BU of 1rxt by Molmil
Crystal structure of human myristoyl-CoA:protein N-myristoyltransferase.
分子名称: COBALT (II) ION, Glycylpeptide N-tetradecanoyltransferase 1, SULFATE ION
著者Yang, J, Wang, Y, Frey, G, Abeles, R.H, Petsko, G.A, Ringe, D.
登録日2003-12-18
公開日2005-04-12
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Crystal structure of human myristoyl-CoA:protein N-myristoyltransferase
To be Published
6PZP
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BU of 6pzp by Molmil
Crystal structure of caspase-1 in complex with VX-765
分子名称: Caspase-1, N-(4-amino-3-chlorobenzene-1-carbonyl)-3-methyl-L-valyl-N-[(2S)-1-carboxy-3-oxopropan-2-yl]-L-prolinamide
著者Yang, J, Liu, Z, Xiao, T.S.
登録日2019-08-01
公開日2020-08-05
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献Crystal structure of caspase-1 in complex with VX-765
To Be Published
3R4L
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BU of 3r4l by Molmil
Human very long half life Plasminogen Activator Inhibitor type-1
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Plasminogen activator inhibitor 1, beta-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose
著者Yang, J, Zheng, H, Han, Q, Skrzypczak-Jankun, E, Jankun, J.
登録日2011-03-17
公開日2011-11-02
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Remarkable extension of PAI-1 half-life surprisingly brings no changes to its structure.
Int.J.Mol.Med., 29, 2012
3QAL
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BU of 3qal by Molmil
Crystal Structure of Arg280Ala mutant of Catalytic subunit of cAMP-dependent Protein Kinase
分子名称: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Protein kinase inhibitor, ...
著者Yang, J, Wu, J, Steichen, J, Taylor, S.S.
登録日2011-01-11
公開日2011-12-07
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献A conserved Glu-Arg salt bridge connects coevolved motifs that define the eukaryotic protein kinase fold.
J.Mol.Biol., 415, 2012
5YLS
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BU of 5yls by Molmil
Crystal structure of T2R-TTL-Y50 complex
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, E-3-(3-azanyl-4-methoxy-phenyl)-1-(5-methoxy-2,2-dimethyl-chromen-8-yl)prop-2-en-1-one, ...
著者Yang, J.H, Chen, L.J.
登録日2017-10-18
公開日2018-04-11
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献The compound millepachine and its derivatives inhibit tubulin polymerization by irreversibly binding to the colchicine-binding site in beta-tubulin.
J. Biol. Chem., 293, 2018
5YLJ
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BU of 5ylj by Molmil
Crystal structure of T2R-TTL-Millepachine complex
分子名称: (E)-1-(5-methoxy-2,2-dimethyl-chromen-8-yl)-3-(4-methoxyphenyl)prop-2-en-1-one, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ...
著者Yang, J.H, Chen, L.J.
登録日2017-10-17
公開日2018-04-11
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献The compound millepachine and its derivatives inhibit tubulin polymerization by irreversibly binding to the colchicine-binding site in beta-tubulin.
J. Biol. Chem., 293, 2018
3PYY
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BU of 3pyy by Molmil
Discovery and Characterization of a Cell-Permeable, Small-molecule c-Abl Kinase Activator that Binds to the Myristoyl Binding Site
分子名称: (5R)-5-[3-(4-fluorophenyl)-1-phenyl-1H-pyrazol-4-yl]imidazolidine-2,4-dione, 4-(4-METHYL-PIPERAZIN-1-YLMETHYL)-N-[4-METHYL-3-(4-PYRIDIN-3-YL-PYRIMIDIN-2-YLAMINO)-PHENYL]-BENZAMIDE, GLYCEROL, ...
著者Yang, J, Campobasso, N, Biju, M.P, Fisher, K, Pan, X.Q, Cottom, J, Galbraith, S, Ho, T, Zhang, H, Hong, X, Ward, P, Hofmann, G, Siegfried, B.
登録日2010-12-13
公開日2011-03-09
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Discovery and Characterization of a Cell-Permeable, Small-Molecule c-Abl Kinase Activator that Binds to the Myristoyl Binding Site.
Chem.Biol., 18, 2011
1O6K
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Structure of activated form of PKB kinase domain S474D with GSK3 peptide and AMP-PNP
分子名称: GLYCOGEN SYNTHASE KINASE-3 BETA, MANGANESE (II) ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
著者Yang, J, Cron, P, Good, V.M, Thompson, V, Hemmings, B.A, Barford, D.
登録日2002-10-08
公開日2002-11-19
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal Structure of an Activated Akt/Protein Kinase B Ternary Complex with Gsk-3 Peptide and AMP-Pnp
Nat.Struct.Biol., 9, 2002
1O6L
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Crystal structure of an activated Akt/protein kinase B (PKB-PIF chimera) ternary complex with AMP-PNP and GSK3 peptide
分子名称: GLYCOGEN SYNTHASE KINASE-3 BETA, MANGANESE (II) ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
著者Yang, J, Cron, P, Good, V.M, Thompson, V, Hemmings, B.A, Barford, D.
登録日2002-10-08
公開日2002-11-19
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Crystal Structure of an Activated Akt/Protein Kinase B Ternary Complex with Gsk-3 Peptide and AMP-Pnp
Nat.Struct.Biol., 9, 2002
2JM1
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BU of 2jm1 by Molmil
Structures and chemical shift assignments for the ADD domain of the ATRX protein
分子名称: Transcriptional regulator ATRX, ZINC ION
著者Yang, J, Neuhaus, D.
登録日2006-09-13
公開日2007-06-26
最終更新日2024-05-08
実験手法SOLUTION NMR
主引用文献Structural consequences of disease-causing mutations in the ATRX-DNMT3-DNMT3L (ADD) domain of the chromatin-associated protein ATRX.
Proc.Natl.Acad.Sci.USA, 104, 2007
1NFF
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BU of 1nff by Molmil
Crystal structure of Rv2002 gene product from Mycobacterium tuberculosis
分子名称: NICOTINAMIDE-ADENINE-DINUCLEOTIDE, Putative oxidoreductase Rv2002
著者Yang, J.K, Park, M.S, Waldo, G.S, Suh, S.W, TB Structural Genomics Consortium (TBSGC)
登録日2002-12-14
公開日2002-12-30
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Directed evolution approach to a structural genomics project: Rv2002 from Mycobacterium tuberculosis
Proc.Natl.Acad.Sci.USA, 100, 2003
2KNC
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BU of 2knc by Molmil
Platelet integrin ALFAIIB-BETA3 transmembrane-cytoplasmic heterocomplex
分子名称: Integrin alpha-IIb, Integrin beta-3
著者Yang, J, Ma, Y, Page, R.C, Misra, S, Plow, E.F, Qin, J.
登録日2009-08-20
公開日2009-09-29
最終更新日2024-05-08
実験手法SOLUTION NMR
主引用文献Structure of an integrin alphaIIb beta3 transmembrane-cytoplasmic heterocomplex provides insight into integrin activation.
Proc.Natl.Acad.Sci.USA, 106, 2009
6LPX
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BU of 6lpx by Molmil
Crystal structure of human D-2-hydroxyglutarate dehydrogenase in complex with 2-oxoglutarate (2-OG)
分子名称: 2-OXOGLUTARIC ACID, D-2-hydroxyglutarate dehydrogenase, mitochondrial, ...
著者Yang, J, Zhu, H, Ding, J.
登録日2020-01-12
公開日2021-01-13
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure, substrate specificity, and catalytic mechanism of human D-2-HGDH and insights into pathogenicity of disease-associated mutations.
Cell Discov, 7, 2021

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件を2024-08-21に公開中

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