1O6K

Structure of activated form of PKB kinase domain S474D with GSK3 peptide and AMP-PNP

Summary for 1O6K

• Entry DOI: 10.2210/pdb1o6k/pdb
• Related: 1GZK 1GZN 1GZO 1O6L
• Descriptor: RAC-BETA SERINE/THREONINE PROTEIN KINASE, GLYCOGEN SYNTHASE KINASE-3 BETA, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... (5 entities in total)
• Functional Keywords: protein kinase, transferase, serine/threonine-protein kinase
• Biological source: HOMO SAPIENS (HUMAN); More
• Cellular location: Cytoplasm: P49841
• Total number of polymer chains: 2
• Total formula weight: 40860.94

Authors

Yang, J.,Cron, P.,Good, V.M.,Thompson, V.,Hemmings, B.A.,Barford, D. (deposition date: 2002-10-08, release date: 2002-11-19, Last modification date: 2011-07-13)

• Primary citation: Yang, J.,Cron, P.,Good, V.M.,Thompson, V.,Hemmings, B.A.,Barford, D.; Crystal Structure of an Activated Akt/Protein Kinase B Ternary Complex with Gsk-3 Peptide and AMP-Pnp; Nat.Struct.Biol., 9:940-, 2002; PubMed: 12434148; DOI: 10.1038/NSB870

Experimental method

X-RAY DIFFRACTION (1.7 Å)