1O6K
Structure of activated form of PKB kinase domain S474D with GSK3 peptide and AMP-PNP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | RAC-BETA SERINE/THREONINE PROTEIN KINASE | polymer | 336 | 39121.6 | 1 | UniProt (P31751) Pfam (PF00069) Pfam (PF00433) | HOMO SAPIENS (HUMAN) | RAC-PK-BETA, PROTEIN KINASE AKT-2, PROTEIN KINASE B, BETA, PKB BETA, PROTEIN KINASE BETA, AKT2 |
| 2 | B (C) | GLYCOGEN SYNTHASE KINASE-3 BETA | polymer | 10 | 1123.2 | 1 | UniProt (P49841) | HOMO SAPIENS (HUMAN) | GSK-3 BETA |
| 3 | C (A) | PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | non-polymer | 506.2 | 1 | Chemie (ANP) | |||
| 4 | D, E (A) | MANGANESE (II) ION | non-polymer | 54.9 | 2 | Chemie (MN) PubChem (27854) | |||
| 5 | F, G (A, C) | water | water | 18.0 | 281 | Chemie (HOH) |
Sequence modifications
A: 146 - 481 (UniProt: P31751)
| PDB | External Database | Details |
|---|---|---|
| Asp 474 | Ser 474 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 40244.9 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 616.1 | |
| All* | Total formula weight | 40860.9 |
