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PDB: 514 件

5KG4
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Human DNA polymerase eta-DNA ternary complex: reaction first with 1 mM Mn2+ for 1800s then with 10 mM Mg2+ for 60s
分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DIPHOSPHATE, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*TP*A)-3'), ...
著者Gao, Y, Yang, W.
登録日2016-06-12
公開日2016-06-22
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Capture of a third Mg2+ is essential for catalyzing DNA synthesis.
Science, 352, 2016
4DXY
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Crystal structures of CYP101D2 Y96A mutant
分子名称: Cytochrome P450, DI(HYDROXYETHYL)ETHER, PROTOPORPHYRIN IX CONTAINING FE
著者Zhou, W, Bell, S.G, Yang, W, Dale, A, Wong, L.-L.
登録日2012-02-28
公開日2012-08-15
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Improving the affinity and activity of CYP101D2 for hydrophobic substrates
Appl.Microbiol.Biotechnol., 2012
4E44
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Crystal structure of the hMHF1/hMHF2 Histone-Fold Tetramer
分子名称: Centromere protein S, Centromere protein X
著者Fox III, D, Zhao, Y, Yang, W, Weidong, W.
登録日2012-03-12
公開日2013-03-20
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal Structures Reveal that FANCM remodels the MHF Tetramer in favor of binding Branched DNA
To be Published
5ZE1
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Hairpin Forming Complex, RAG1/2-Nicked 12RSS/23RSS complex in 2mM Mn2+ for 10 min at 4'C
分子名称: 1,2-ETHANEDIOL, DNA, HMGB1 A-B box, ...
著者Kim, M.S, Chuenchor, W, Chen, X, Gellert, M, Yang, W.
登録日2018-02-25
公開日2018-04-25
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Cracking the DNA Code for V(D)J Recombination
Mol. Cell, 70, 2018
4EGO
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BU of 4ego by Molmil
The X-ray crystal structure of CYP199A4 in complex with indole-6-carboxylic acid
分子名称: 1H-indole-6-carboxylic acid, CHLORIDE ION, Cytochrome P450, ...
著者Zhou, W, Bell, S.G, Yang, W, Zhou, R.M, Tan, A.B.H, Wong, L.-L.
登録日2012-03-31
公開日2013-02-20
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.76 Å)
主引用文献Investigation of the substrate range of CYP199A4: modification of the partition between hydroxylation and desaturation activities by substrate and protein engineering
Chemistry, 18, 2012
4EGM
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The X-ray crystal structure of CYP199A4 in complex with 4-ethylbenzoic acid
分子名称: 4-ethylbenzoic acid, CHLORIDE ION, Cytochrome P450, ...
著者Zhou, W, Bell, S.G, Yang, W, Zhou, R.M, Tan, A.B.H, Wong, L.-L.
登録日2012-03-31
公開日2013-02-20
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.91 Å)
主引用文献Investigation of the substrate range of CYP199A4: modification of the partition between hydroxylation and desaturation activities by substrate and protein engineering
Chemistry, 18, 2012
4E45
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Crystal structure of the hMHF1/hMHF2 Histone-Fold Tetramer in Complex with Fanconi Anemia Associated Helicase hFANCM
分子名称: Centromere protein S, Centromere protein X, Fanconi anemia group M protein, ...
著者Fox III, D, Zhao, Y, Yang, W, Weidong, W.
登録日2012-03-12
公開日2013-03-20
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal Structures Reveal that FANCM remodels the MHF Tetramer in favor of binding Branched DNA
To be Published
4EGN
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BU of 4egn by Molmil
The X-ray crystal structure of CYP199A4 in complex with veratric acid
分子名称: 3,4-dimethoxybenzoic acid, CHLORIDE ION, Cytochrome P450, ...
著者Zhou, W, Bell, S.G, Yang, W, Zhou, R.M, Tan, A.B.H, Wong, L.-L.
登録日2012-03-31
公開日2013-02-20
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Investigation of the substrate range of CYP199A4: modification of the partition between hydroxylation and desaturation activities by substrate and protein engineering
Chemistry, 18, 2012
1EWR
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BU of 1ewr by Molmil
CRYSTAL STRUCTURE OF TAQ MUTS
分子名称: DNA MISMATCH REPAIR PROTEIN MUTS
著者Obmolova, G, Ban, C, Hsieh, P, Yang, W.
登録日2000-04-26
公開日2000-10-23
最終更新日2018-06-27
実験手法X-RAY DIFFRACTION (3.19 Å)
主引用文献Crystal structures of mismatch repair protein MutS and its complex with a substrate DNA.
Nature, 407, 2000
1EA6
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N-terminal 40kDa fragment of NhPMS2 complexed with ADP
分子名称: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PMS1 PROTEIN HOMOLOG 2
著者Guarne, A, Junop, M.S, Yang, W.
登録日2001-07-10
公開日2001-11-23
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structure and Function of the N-Terminal 40 kDa Fragment of Human Pms2: A Monomeric Ghl ATPase
Embo J., 20, 2001
1EWQ
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CRYSTAL STRUCTURE TAQ MUTS COMPLEXED WITH A HETERODUPLEX DNA AT 2.2 A RESOLUTION
分子名称: 1,2-ETHANEDIOL, DNA (5'-D(*GP*CP*GP*AP*CP*GP*CP*TP*AP*GP*CP*GP*TP*GP*CP*GP*GP*CP*TP*CP*GP*TP*C)-3'), DNA (5'-D(*GP*GP*AP*CP*GP*AP*GP*CP*CP*GP*CP*CP*GP*CP*TP*AP*GP*CP*GP*TP*CP*G)-3'), ...
著者Obmolova, G, Ban, C, Hsieh, P, Yang, W.
登録日2000-04-26
公開日2000-10-23
最終更新日2021-11-03
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structures of mismatch repair protein MutS and its complex with a substrate DNA.
Nature, 407, 2000
2YPS
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BU of 2yps by Molmil
Crystal structure of the PX domain of human sorting nexin 3
分子名称: SORTING NEXIN-3
著者Canning, P, Kiyani, W, Froese, D.S, Krojer, T, Strain-Damerell, C, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Yue, W.W.
登録日2012-10-31
公開日2013-03-20
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal Structure of the Px Domain of Human Sorting Nexin 3
To be Published
5D47
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Crystal Structure of FABP4 in complex with 3-[5-cyclopropyl-3-(3-methoxypyridin-4-yl)-2-phenyl-1H-indol-1-yl] propanoic acid
分子名称: 3-[5-cyclopropyl-3-(3-methoxypyridin-4-yl)-2-phenyl-1H-indol-1-yl]propanoic acid, Fatty acid-binding protein, adipocyte
著者Tagami, U, Takahashi, K, Igarashi, S, Ejima, C, Yoshida, T, Takeshita, S, Miyanaga, W, Sugiki, M, Tokumasu, M, Hatanaka, T, Kashiwagi, T, Ishikawa, K, Miyano, H, Mizukoshi, T.
登録日2015-08-07
公開日2016-06-22
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Interaction Analysis of FABP4 Inhibitors by X-ray Crystallography and Fragment Molecular Orbital Analysis
Acs Med.Chem.Lett., 7, 2016
6C2U
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BU of 6c2u by Molmil
Solution structure of a phosphate-loop protein
分子名称: phosphate-loop protein
著者Yang, F, Yang, W, Lin, Y.R, Romero Romero, M.L, Tawfik, D, Baker, D, Varani, G.
登録日2018-01-09
公開日2018-11-21
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Simple yet functional phosphate-loop proteins.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6C2V
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BU of 6c2v by Molmil
Solution structure of a phosphate-loop protein
分子名称: phosphate-loop protein
著者Yang, F, Yang, W, Lin, Y.R, Romero Romero, M.L, Tawfik, D, Baker, D, Varani, G.
登録日2018-01-09
公開日2018-11-21
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Simple yet functional phosphate-loop proteins.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
8I0K
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BU of 8i0k by Molmil
Cryo-electron microscopic structure of the 2-oxoglutarate dehydrogenase(E1) with TCAIM complex
分子名称: 2-[3-[(4-azanyl-2-methyl-pyrimidin-5-yl)methyl]-4-methyl-2H-1,3-thiazol-5-yl]ethyl phosphono hydrogen phosphate, 2-oxoglutarate dehydrogenase complex component E1, CALCIUM ION, ...
著者Yu, X, Yang, W, Zhong, Y.H, Ma, X.M, Gao, Y.Z.
登録日2023-01-11
公開日2024-05-01
実験手法ELECTRON MICROSCOPY (2.86 Å)
主引用文献Cryo-electron microscopic structure of the 2-oxoglutarate dehydrogenase (E1) with TCAIM complex
To Be Published
2IMW
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BU of 2imw by Molmil
Mechanism of Template-Independent Nucleotide Incorporation Catalyzed by a Template-Dependent DNA Polymerase
分子名称: 1,2-ETHANEDIOL, 2',3'-dideoxyadenosine triphosphate, 5'-D(*GP*GP*GP*GP*GP*AP*AP*GP*GP*AP*TP*TP*C)-3', ...
著者Ling, H, Yang, W.
登録日2006-10-05
公開日2007-01-16
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Mechanism of Template-independent Nucleotide Incorporation Catalyzed by a Template-dependent DNA Polymerase.
J.Mol.Biol., 365, 2007
1U2J
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BU of 1u2j by Molmil
Crystal structure of the C-terminal domain from the catalase-peroxidase KatG of Escherichia coli (P21 21 21)
分子名称: Peroxidase/catalase HPI
著者Carpena, X, Melik-Adamyan, W, Loewen, P.C, Fita, I.
登録日2004-07-19
公開日2004-10-05
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure of the C-terminal domain of the catalase-peroxidase KatG from Escherichia coli.
Acta Crystallogr.,Sect.D, 60, 2004
1U2K
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Crystal structure of the C-terminal domain from the catalase-peroxidase KatG of Escherichia coli (I41)
分子名称: Peroxidase/catalase HPI
著者Carpena, X, Melik-Adamyan, W, Loewen, P.C, Fita, I.
登録日2004-07-19
公開日2004-10-05
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure of the C-terminal domain of the catalase-peroxidase KatG from Escherichia coli.
Acta Crystallogr.,Sect.D, 60, 2004
6LAE
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BU of 6lae by Molmil
Crystal structure of the DNA-binding domain of human XPA in complex with DNA
分子名称: DNA (5'-D(P*GP*CP*AP*TP*CP*TP*CP*GP*CP*CP*T)-3'), DNA (5'-D(P*TP*GP*GP*CP*GP*AP*GP*AP*TP*GP*C)-3'), DNA repair protein complementing XP-A cells, ...
著者Lian, F.M, Yang, X, Jiang, Y.L, Yang, F, Li, C, Yang, W, Qian, C.
登録日2019-11-12
公開日2020-02-26
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.81 Å)
主引用文献New structural insights into the recognition of undamaged splayed-arm DNA with a single pair of non-complementary nucleotides by human nucleotide excision repair protein XPA.
Int.J.Biol.Macromol., 148, 2020
4N7V
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BU of 4n7v by Molmil
Crystal structure of human Plk4 cryptic polo box (CPB) in complex with a Cep152 N-terminal fragment
分子名称: Centrosomal protein of 152 kDa, Serine/threonine-protein kinase PLK4
著者Park, S.-Y, Park, J.-E, Tian, L, Kim, T.-S, Yang, W, Lee, K.S.
登録日2013-10-16
公開日2014-07-02
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.758 Å)
主引用文献Molecular basis for unidirectional scaffold switching of human Plk4 in centriole biogenesis.
Nat.Struct.Mol.Biol., 21, 2014
4COO
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BU of 4coo by Molmil
Crystal structure of human cystathionine beta-synthase (delta516-525) at 2.0 angstrom resolution
分子名称: 1,2-ETHANEDIOL, 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, ACETATE ION, ...
著者McCorvie, T.J, Kopec, J, Vollamar, M, Strain-Damerell, C, Bushell, S, Bradley, A, Tallant, C, Kiyani, W, Froese, D.S, Carpenter, E.S, Burgess-Brown, N, von Delft, F, Arrowsmith, C, Edwards, A, Bountra, C, Yue, W.W.
登録日2014-01-29
公開日2014-03-05
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Inter-Domain Communication of Human Cystathionine Beta Synthase: Structural Basis of S-Adenosyl-L-Methionine Activation.
J.Biol.Chem., 289, 2014
4N7Z
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Crystal structure of human Plk4 cryptic polo box (CPB) in complex with a Cep192 N-terminal fragment
分子名称: Centrosomal protein of 192 kDa, Serine/threonine-protein kinase PLK4
著者Park, S.-Y, Park, J.-E, Tian, L, Kim, T.-S, Yang, W, Lee, K.S.
登録日2013-10-16
公開日2014-07-02
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Molecular basis for unidirectional scaffold switching of human Plk4 in centriole biogenesis.
Nat.Struct.Mol.Biol., 21, 2014
1U2L
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Crystal structure of the C-terminal domain from the catalase-peroxidase KatG of Escherichia coli (P1)
分子名称: Peroxidase/catalase HPI
著者Carpena, X, Melik-Adamyan, W, Loewen, P.C, Fita, I.
登録日2004-07-19
公開日2004-10-05
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure of the C-terminal domain of the catalase-peroxidase KatG from Escherichia coli.
Acta Crystallogr.,Sect.D, 60, 2004
4Q8E
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Human DNA polymerase eta inserting dCMPNPP opposite a phenanthriplatin adducted G
分子名称: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidine, 5'-D(*AP*GP*TP*GP*TP*GP*AP*G)-3', 5'-D(*CP*AP*TP*GP*CP*TP*CP*AP*CP*AP*CP*T)-3', ...
著者Gregory, M.T, Yang, W.
登録日2014-04-26
公開日2014-07-02
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.549 Å)
主引用文献Structural and mechanistic studies of polymerase eta bypass of phenanthriplatin DNA damage.
Proc.Natl.Acad.Sci.USA, 111, 2014

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