4E44

Crystal structure of the hMHF1/hMHF2 Histone-Fold Tetramer

Summary for 4E44

Related4E45
DescriptorCentromere protein S, Centromere protein X (3 entities in total)
Functional Keywordshistone-fold, tetramer, fanconi anemia, fancm, mhf, dna binding protein
Biological sourceHomo sapiens (human)
Cellular locationNucleus  Q8N2Z9 A8MT69
Total number of polymer chains4
Total molecular weight44318.48
Authors
Fox III, D.,Zhao, Y.,Yang, W.,Weidong, W. (deposition date: 2012-03-12, release date: 2013-03-20, Last modification date: 2018-01-24)
Primary citation
Fox III, D.,Yan, Z.,Ling, C.,Zhao, Y.,Lee, D.Y.,Yang, W.,Weidong, W.
Crystal Structures Reveal that FANCM remodels the MHF Tetramer in favor of binding Branched DNA
To be Published,
Experimental method
X-RAY DIFFRACTION (2.1 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.234201.1%1.7%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution