4E44

Crystal structure of the hMHF1/hMHF2 Histone-Fold Tetramer

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C	Centromere protein S	polymer	112	13042.7	2	UniProt (Q8N2Z9) Pfam (PF15630) In PDB	Homo sapiens (human)	CENP-S, Apoptosis-inducing TAF9-like domain-containing protein 1, FANCM-interacting histone fold protein 1, Fanconi anemia-associated polypeptide of 16 kDa
2	B, D	Centromere protein X	polymer	83	9116.5	2	UniProt (A8MT69) Pfam (PF09415) In PDB	Homo sapiens (human)	CENP-X, FANCM-interacting histone fold protein 2, Fanconi anemia-associated polypeptide of 10 kDa, Retinoic acid-inducible gene D9 protein homolog, Stimulated by retinoic acid gene 13 protein homolog
3		water	water		18.0	97	Chemie (HOH)

Sequence modifications

A, C: 1 - 110 (UniProt: Q8N2Z9)

PDB	External Database	Details
Gly -1	-	expression tag
Ser 0	-	expression tag

B, D: 1 - 81 (UniProt: A8MT69)

PDB	External Database	Details
Gly -1	-	expression tag
Ser 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	44318.5
All*	Total formula weight	44318.5

*Water molecules are not included.