5D47

Crystal Structure of FABP4 in complex with 3-[5-cyclopropyl-3-(3-methoxypyridin-4-yl)-2-phenyl-1H-indol-1-yl] propanoic acid

Summary for 5D47

Entry DOI	10.2210/pdb5d47/pdb
Related	5D45 5D48 5D4A
Descriptor	Fatty acid-binding protein, adipocyte, 3-[5-cyclopropyl-3-(3-methoxypyridin-4-yl)-2-phenyl-1H-indol-1-yl]propanoic acid (3 entities in total)
Functional Keywords	fatty acid binding protein, lipid binding protein
Biological source	Homo sapiens (Human)
Total number of polymer chains	1
Total formula weight	17323.75
Authors	Tagami, U.,Takahashi, K.,Igarashi, S.,Ejima, C.,Yoshida, T.,Takeshita, S.,Miyanaga, W.,Sugiki, M.,Tokumasu, M.,Hatanaka, T.,Kashiwagi, T.,Ishikawa, K.,Miyano, H.,Mizukoshi, T. (deposition date: 2015-08-07, release date: 2016-06-22, Last modification date: 2023-11-08)
Primary citation	Tagami, U.,Takahashi, K.,Igarashi, S.,Ejima, C.,Yoshida, T.,Takeshita, S.,Miyanaga, W.,Sugiki, M.,Tokumasu, M.,Hatanaka, T.,Kashiwagi, T.,Ishikawa, K.,Miyano, H.,Mizukoshi, T. Interaction Analysis of FABP4 Inhibitors by X-ray Crystallography and Fragment Molecular Orbital Analysis Acs Med.Chem.Lett., 7:435-439, 2016 Cited by PubMed: 27096055 DOI: 10.1021/acsmedchemlett.6b00040 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.7 Å)

Structure validation