3SAN
 
 | | Crystal structure of influenza A virus neuraminidase N5 complexed with Zanamivir | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | | Authors: | Wang, M.Y, Qi, J.X, Liu, Y, Vavricka, C.J, Wu, Y, Li, Q, Gao, G.F. | | Deposit date: | 2011-06-03 | | Release date: | 2011-08-10 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Influenza a virus n5 neuraminidase has an extended 150-cavity
J.Virol., 85, 2011
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3SAL
 | | Crystal Structure of Influenza A Virus Neuraminidase N5 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, GLYCEROL, ... | | Authors: | Wang, M.Y, Qi, J.X, Liu, Y, Vavricka, C.J, Wu, Y, Li, Q, Gao, G.F. | | Deposit date: | 2011-06-03 | | Release date: | 2011-08-10 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Influenza a virus n5 neuraminidase has an extended 150-cavity
J.Virol., 85, 2011
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2B21
 | | RADA Recombinase in complex with AMPPNP at pH 6.0 | | Descriptor: | DNA repair and recombination protein radA, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | | Authors: | Qian, X, He, Y, Wu, Y, Luo, Y. | | Deposit date: | 2005-09-16 | | Release date: | 2006-08-29 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Crystal Structure of Methanococcus Voltae Rada at an Acidic pH
To be Published
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5G06
 | | Cryo-EM structure of yeast cytoplasmic exosome | | Descriptor: | EXOSOME COMPLEX COMPONENT CSL4, EXOSOME COMPLEX COMPONENT MTR3, EXOSOME COMPLEX COMPONENT RRP4, ... | | Authors: | Liu, J.J, Niu, C.Y, Wu, Y, Tan, D, Wang, Y, Ye, M.D, Liu, Y, Zhao, W.W, Zhou, K, Liu, Q.S, Dai, J.B, Yang, X.R, Dong, M.Q, Huang, N, Wang, H.W. | | Deposit date: | 2016-03-17 | | Release date: | 2016-06-15 | | Last modified: | 2017-08-02 | | Method: | ELECTRON MICROSCOPY (4.2 Å) | | Cite: | Cryoem Structure of Yeast Cytoplasmic Exosome Complex.
Cell Res., 26, 2016
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5AFG
 | | Structure of the Stapled Peptide Bound to Mdm2 | | Descriptor: | 1,8-DIETHYL-1,8-DIHYDRODIBENZO[3,4:7,8][1,2,3]TRIAZOLO[4',5':5,6]CYCLOOCTA[1,2-D][1,2,3]TRIAZOLE, E3 UBIQUITIN-PROTEIN LIGASE MDM2, STAPLED PEPTIDE | | Authors: | Lau, Y.H, Wu, Y, Rossmann, M, de Andrade, P, Tan, Y.S, McKenzie, G.J, Venkitaraman, A.R, Hyvonen, M, Spring, D.R. | | Deposit date: | 2015-01-22 | | Release date: | 2016-01-27 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Double Strain-Promoted Macrocyclization for the Rapid Selection of Cell-Active Stapled Peptides.
Angew.Chem.Int.Ed.Engl., 54, 2015
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8HHZ
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8HDZ
 | | Monkeypox virus DNA replication holoenzyme F8, A22 and E4 complex in an apo form | | Descriptor: | A22 DNA replication processivity factor, E4 uracil-DNA glycosylase, F8 DNA polymerase | | Authors: | Xu, Y, Wu, Y, Zhang, Y, Fan, R, Yang, Y, Li, D, Yang, B, Zhang, Z, Dong, C. | | Deposit date: | 2022-11-07 | | Release date: | 2023-11-15 | | Method: | ELECTRON MICROSCOPY (3.05 Å) | | Cite: | Cryo-EM structures of human monkeypox viral replication complexes with and without DNA duplex.
Cell Res., 33, 2023
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4DKE
 | | Crystal Structure of Human Interleukin-34 Bound to FAb1.1 | | Descriptor: | FAb1.1 Heavy Chain, FAb1.1 Light Chain, Interleukin-34, ... | | Authors: | Ma, X, Chen, Y, Stawicki, S, Wu, Y, Bazan, J.F, Starovasnik, M.A. | | Deposit date: | 2012-02-03 | | Release date: | 2012-04-11 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Structural Basis for the Dual Recognition of Helical Cytokines IL-34 and CSF-1 by CSF-1R.
Structure, 20, 2012
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4DKF
 | | Crystal Structure of Human Interleukin-34 Bound to FAb2 | | Descriptor: | FAb2 Heavy Chain, FAb2 Light Chain, Interleukin-34, ... | | Authors: | Ma, X, Chen, Y, Stawicki, S, Wu, Y, Bazan, J.F, Starovasnik, M.A. | | Deposit date: | 2012-02-03 | | Release date: | 2012-04-11 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (2.61 Å) | | Cite: | Structural Basis for the Dual Recognition of Helical Cytokines IL-34 and CSF-1 by CSF-1R.
Structure, 20, 2012
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2QLD
 | | human Hsp40 Hdj1 | | Descriptor: | DnaJ homolog subfamily B member 1 | | Authors: | Hu, J, Wu, Y, Li, J, Fu, Z, Sha, B. | | Deposit date: | 2007-07-12 | | Release date: | 2008-07-15 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | The crystal structure of the putative peptide-binding fragment from the human Hsp40 protein Hdj1.
Bmc Struct.Biol., 8, 2008
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5HLJ
 | | Crystal Structure of Major Envelope Protein VP24 from White Spot Syndrome Virus | | Descriptor: | VP24 | | Authors: | Sun, L.F, Su, Y.T, Zhao, Y.H, Fu, Z.Q, Wu, Y.K. | | Deposit date: | 2016-01-15 | | Release date: | 2016-09-14 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.406 Å) | | Cite: | Crystal Structure of Major Envelope Protein VP24 from White Spot Syndrome Virus
Sci Rep, 6, 2016
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8JZY
 | | RPA70N-RAD9 fusion | | Descriptor: | Cell cycle checkpoint control protein RAD9A, Replication protein A 70 kDa DNA-binding subunit | | Authors: | Fu, W.M, Wu, Y.Y, Zhou, C. | | Deposit date: | 2023-07-06 | | Release date: | 2023-09-13 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Structural characterization of human RPA70N association with DNA damage response proteins.
Elife, 12, 2023
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8JZV
 | | RPA70N-ETAA1 fusion | | Descriptor: | Ewing's tumor-associated antigen 1, Replication protein A 70 kDa DNA-binding subunit | | Authors: | Fu, W.M, Wu, Y.Y, Zhou, C. | | Deposit date: | 2023-07-06 | | Release date: | 2023-09-13 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Structural characterization of human RPA70N association with DNA damage response proteins.
Elife, 12, 2023
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8K00
 | | RPA70N-MRE11 fusion | | Descriptor: | Double-strand break repair protein MRE11, Replication protein A 70 kDa DNA-binding subunit | | Authors: | Fu, W.M, Wu, Y.Y, Zhou, C. | | Deposit date: | 2023-07-07 | | Release date: | 2023-09-13 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | Structural characterization of human RPA70N association with DNA damage response proteins.
Elife, 12, 2023
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3SOB
 | | The structure of the first YWTD beta propeller domain of LRP6 in complex with a FAB | | Descriptor: | CALCIUM ION, Low-density lipoprotein receptor-related protein 6, antibody heavy chain, ... | | Authors: | Wang, W, Bourhis, E, Tam, C, Zhang, Y, Rouge, L, Wu, Y, Franke, Y, Cochran, A.G. | | Deposit date: | 2011-06-30 | | Release date: | 2011-09-21 | | Last modified: | 2014-05-14 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Wnt antagonists bind through a short peptide to the first beta-propeller domain of LRP5/6.
Structure, 19, 2011
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3SOQ
 | | The structure of the first YWTD beta propeller domain of LRP6 in complex with a DKK1 peptide | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Dickkopf-related protein 1, ... | | Authors: | Wang, W, Bourhis, E, Zhang, Y, Rouge, L, Wu, Y, Franke, Y, Cochran, A.G. | | Deposit date: | 2011-06-30 | | Release date: | 2011-09-21 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Wnt antagonists bind through a short peptide to the first beta-propeller domain of LRP5/6.
Structure, 19, 2011
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5E00
 | | Structure of HLA-A2 P130 | | Descriptor: | Beta-2-microglobulin, GLY-VAL-TRP-ILE-ARG-THR-PRO-PRO-ALA, HLA class I histocompatibility antigen, ... | | Authors: | Zhang, Y, Wu, Y, Qi, J, Liu, J, Gao, G.F, Meng, S. | | Deposit date: | 2015-09-26 | | Release date: | 2017-01-18 | | Last modified: | 2019-01-23 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | CD8+T-Cell Response-Associated Evolution of Hepatitis B Virus Core Protein and Disease Progress.
J. Virol., 92, 2018
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3SOV
 | | The structure of a beta propeller domain in complex with peptide S | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, Low-density lipoprotein receptor-related protein 6, ... | | Authors: | Wang, W, Bourhis, E, Zhang, Y, Rouge, L, Wu, Y, Franke, Y, Cochran, A.G. | | Deposit date: | 2011-06-30 | | Release date: | 2011-09-21 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (1.27 Å) | | Cite: | Wnt antagonists bind through a short peptide to the first beta-propeller domain of LRP5/6.
Structure, 19, 2011
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4BZC
 | | Crystal structure of the tetrameric dGTP-bound wild type SAMHD1 catalytic core | | Descriptor: | 2'-deoxyguanosine-5'-O-(1-thiotriphosphate), DEOXYNUCLEOSIDE TRIPHOSPHATE TRIPHOSPHOHYDROLASE SAMHD1, MAGNESIUM ION, ... | | Authors: | Ji, X, Yang, H, Wu, Y, Yan, J, Mehrens, J, DeLucia, M, Hao, C, Gronenborn, A.M, Skowronski, J, Ahn, J, Xiong, Y. | | Deposit date: | 2013-07-25 | | Release date: | 2013-10-23 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.88 Å) | | Cite: | Mechanism of Allosteric Activation of Samhd1 by Dgtp
Nat.Struct.Mol.Biol., 20, 2013
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4BZB
 | | Crystal structure of the tetrameric dGTP-bound SAMHD1 mutant catalytic core | | Descriptor: | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DEOXYNUCLEOSIDE TRIPHOSPHATE TRIPHOSPHOHYDROLASE SAMHD1, MAGNESIUM ION | | Authors: | Ji, X, Yang, H, Wu, Y, Yan, J, Mehrens, J, DeLucia, M, Hao, C, Gronenborn, A.M, Skowronski, J, Ahn, J, Xiong, Y. | | Deposit date: | 2013-07-25 | | Release date: | 2013-10-23 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (1.83 Å) | | Cite: | Mechanism of Allosteric Activation of Samhd1 by Dgtp
Nat.Struct.Mol.Biol., 20, 2013
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5H3V
 | | Crystal structure of a Type IV Secretion System Component CagX in Helicobacter pylori | | Descriptor: | Cag8, DI(HYDROXYETHYL)ETHER, ISOPROPYL ALCOHOL | | Authors: | Zhang, J, Wu, Y, Zhao, Y, Sun, L, Keegan, R.M, Liu, Y, Isupov, M.N. | | Deposit date: | 2016-10-27 | | Release date: | 2017-04-12 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | Crystal structure of the type IV secretion system component CagX from Helicobacter pylori
Acta Crystallogr F Struct Biol Commun, 73, 2017
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1RII
 | | Crystal structure of phosphoglycerate mutase from M. Tuberculosis | | Descriptor: | 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase, GLYCEROL | | Authors: | Mueller, P, Sawaya, M.R, Chan, S, Wu, Y, Pashkova, I, Perry, J, Eisenberg, D, TB Structural Genomics Consortium (TBSGC) | | Deposit date: | 2003-11-17 | | Release date: | 2004-10-05 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | The 1.70 angstroms X-ray crystal structure of Mycobacterium tuberculosis phosphoglycerate mutase.
Acta Crystallogr.,Sect.D, 61, 2005
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3ME2
 | | Crystal structure of mouse RANKL-RANK complex | | Descriptor: | CHLORIDE ION, SODIUM ION, Tumor necrosis factor ligand superfamily member 11, ... | | Authors: | Walter, S.W, Liu, C.Z, Zhu, X.K, Wu, Y, Owens, R.J, Stuart, D.I, Gao, B, Ren, J. | | Deposit date: | 2010-03-31 | | Release date: | 2010-06-02 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Structural and Functional Insights of RANKL-RANK Interaction and Signaling.
J.Immunol., 2010
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7YQM
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3C72
 | | Engineered RabGGTase in complex with a peptidomimetic inhibitor | | Descriptor: | CALCIUM ION, Geranylgeranyl transferase type-2 subunit alpha, Geranylgeranyl transferase type-2 subunit beta, ... | | Authors: | Guo, Z, Wu, Y.W, Tan, K.T, Bon, R.S, Guiu-Rozas, E, Delon, C, Nguyen, U.T, Wetzel, S, Arndt, S, Goody, R.S, Blankenfeldt, W, Alexandrov, K, Waldmann, H. | | Deposit date: | 2008-02-06 | | Release date: | 2008-07-22 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Development of selective RabGGTase inhibitors and crystal structure of a RabGGTase-inhibitor complex.
Angew.Chem.Int.Ed.Engl., 47, 2008
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