3SOQ
The structure of the first YWTD beta propeller domain of LRP6 in complex with a DKK1 peptide
Summary for 3SOQ
Entry DOI | 10.2210/pdb3soq/pdb |
Related | 3SOB 3SOV |
Descriptor | Low-density lipoprotein receptor-related protein 6, Dickkopf-related protein 1, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total) |
Functional Keywords | beta propeller, protein binding-antagonist complex, protein binding/antagonist |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 2 |
Total formula weight | 36988.32 |
Authors | Wang, W.,Bourhis, E.,Zhang, Y.,Rouge, L.,Wu, Y.,Franke, Y.,Cochran, A.G. (deposition date: 2011-06-30, release date: 2011-09-21, Last modification date: 2020-07-29) |
Primary citation | Bourhis, E.,Wang, W.,Tam, C.,Hwang, J.,Zhang, Y.,Spittler, D.,Huang, O.W.,Gong, Y.,Estevez, A.,Zilberleyb, I.,Rouge, L.,Chiu, C.,Wu, Y.,Costa, M.,Hannoush, R.N.,Franke, Y.,Cochran, A.G. Wnt antagonists bind through a short peptide to the first beta-propeller domain of LRP5/6. Structure, 19:1433-1442, 2011 Cited by PubMed: 21944579DOI: 10.1016/j.str.2011.07.005 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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