3SOQ
The structure of the first YWTD beta propeller domain of LRP6 in complex with a DKK1 peptide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Low-density lipoprotein receptor-related protein 6 | polymer | 318 | 35685.9 | 1 | UniProt (O75581) Pfam (PF00058) Pfam (PF14670) | Homo sapiens (human) | LRP-6 |
| 2 | B (Z) | Dickkopf-related protein 1 | polymer | 9 | 784.9 | 1 | UniProt (O94907) | Homo sapiens | Dickkopf-1, Dkk-1, hDkk-1, SK |
| 3 | C (A) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
| 4 | D (A) | alpha-L-fucopyranose | non-polymer | 164.2 | 1 | Chemie (FUC) | |||
| 5 | E (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 6 | F (A) | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
| 7 | G, H (A, Z) | water | water | 18.0 | 266 | Chemie (HOH) |
Sequence modifications
A: 20 - 326 (UniProt: O75581)
Z: 38 - 44 (UniProt: O94907)
| PDB | External Database | Details |
|---|---|---|
| Ala 17 | - | expression tag |
| Gly 18 | - | expression tag |
| Ser 19 | - | expression tag |
| Asn 327 | - | expression tag |
| Ser 328 | - | expression tag |
| His 329 | - | expression tag |
| His 330 | - | expression tag |
| His 331 | - | expression tag |
| His 332 | - | expression tag |
| His 333 | - | expression tag |
| His 334 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Ace 37 | - | acetylation |
| Nh2 45 | - | amidation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 36470.8 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 517.5 | |
| All* | Total formula weight | 36988.3 |
