5JHH
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![BU of 5jhh by Molmil](/molmil-images/mine/5jhh) | Crystal structure of the ternary complex between the human RhoA, its inhibitor and the DH/PH domain of human ARHGEF11 | Descriptor: | 3-{3-[ethyl(quinolin-2-yl)amino]phenyl}propanoic acid, GLYCEROL, Rho guanine nucleotide exchange factor 11, ... | Authors: | Lv, Z, Wang, R, Ma, L, Miao, Q, Wu, J, Yan, Z, Li, J, Miao, L, Wang, F. | Deposit date: | 2016-04-21 | Release date: | 2017-04-26 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystallization and preliminary X-ray crystallographic analysis of a small GTPase RhoA bound with its inhibitor and PDZRhoGEF To Be Published
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5X6M
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![BU of 5x6m by Molmil](/molmil-images/mine/5x6m) | Crystal Structure of SMAD5-MH1 in complex with a composite DNA sequence | Descriptor: | DNA (5'-D(P*AP*TP*CP*AP*GP*AP*CP*TP*GP*CP*CP*GP*GP*CP*AP*GP*TP*CP*TP*AP*TP*A)-3'), DNA (5'-D(P*TP*TP*AP*TP*AP*GP*AP*CP*TP*GP*CP*CP*GP*GP*CP*AP*GP*TP*CP*TP*GP*A)-3'), Mothers against decapentaplegic homolog 5, ... | Authors: | Chai, N, Wang, J, Wang, Z.X, Wu, J.W. | Deposit date: | 2017-02-22 | Release date: | 2017-03-15 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Structural basis for the Smad5 MH1 domain to recognize different DNA sequences. Nucleic Acids Res., 43, 2015
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7V9L
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![BU of 7v9l by Molmil](/molmil-images/mine/7v9l) | Cryo-EM structure of the SV1-Gs complex. | Descriptor: | GHRH receptor splice variant 1,GHRH receptor splice variant 1,GHRH receptor splice variant 1,SV1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | Cong, Z.T, Zhou, F.L, Zhang, C, Zou, X.Y, Zhang, H.B, Wang, Y.Z, Zhou, Q.T, Cai, X.Q, Liu, Q.F, Li, J, Shao, L.J, Mao, C.Y, Wang, X, Wu, J.H, Xia, T, Zhao, L.H, Jiang, H.L, Zhang, Y, Xu, H.E, Cheng, X, Yang, D.H, Wang, M.W. | Deposit date: | 2021-08-26 | Release date: | 2022-04-06 | Last modified: | 2022-05-04 | Method: | ELECTRON MICROSCOPY (2.6 Å) | Cite: | Constitutive signal bias mediated by the human GHRHR splice variant 1. Proc.Natl.Acad.Sci.USA, 118, 2021
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6JT1
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![BU of 6jt1 by Molmil](/molmil-images/mine/6jt1) | Structure of human soluble guanylate cyclase in the heme oxidised state | Descriptor: | Guanylate cyclase soluble subunit alpha-1, Guanylate cyclase soluble subunit beta-1, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Chen, L, Kang, Y, Liu, R, Wu, J.-X. | Deposit date: | 2019-04-08 | Release date: | 2019-08-28 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Structural insights into the mechanism of human soluble guanylate cyclase. Nature, 574, 2019
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7V9M
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![BU of 7v9m by Molmil](/molmil-images/mine/7v9m) | Cryo-EM structure of the GHRH-bound human GHRHR splice variant 1 complex | Descriptor: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ... | Authors: | Cong, Z.T, Zhou, F.L, Zhang, C, Zou, X.Y, Zhang, H.B, Wang, Y.Z, Zhou, Q.T, Cai, X.Q, Liu, Q.F, Li, J, Shao, L.J, Mao, C.Y, Wang, X, Wu, J.H, Xia, T, Zhao, L.H, Jiang, H.L, Zhang, Y, Xu, H.E, Chen, X, Yang, D.H, Wang, M.W. | Deposit date: | 2021-08-26 | Release date: | 2021-10-20 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (3.29 Å) | Cite: | Constitutive signal bias mediated by the human GHRHR splice variant 1. Proc.Natl.Acad.Sci.USA, 118, 2021
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6JT0
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![BU of 6jt0 by Molmil](/molmil-images/mine/6jt0) | Structure of human soluble guanylate cyclase in the unliganded state | Descriptor: | Guanylate cyclase soluble subunit alpha-1, Guanylate cyclase soluble subunit beta-1, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Chen, L, Kang, Y, Liu, R, Wu, J.-X. | Deposit date: | 2019-04-08 | Release date: | 2019-08-28 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Structural insights into the mechanism of human soluble guanylate cyclase. Nature, 574, 2019
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2HMH
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![BU of 2hmh by Molmil](/molmil-images/mine/2hmh) | |
6J0X
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![BU of 6j0x by Molmil](/molmil-images/mine/6j0x) | Crystal Structure of Yeast Rtt107 and Mms22 | Descriptor: | Peptide from E3 ubiquitin-protein ligase substrate receptor MMS22, Regulator of Ty1 transposition protein 107 | Authors: | Wan, B, Wu, J, Lei, M. | Deposit date: | 2018-12-27 | Release date: | 2019-08-14 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.31 Å) | Cite: | Molecular Basis for Control of Diverse Genome Stability Factors by the Multi-BRCT Scaffold Rtt107. Mol.Cell, 75, 2019
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5X6G
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![BU of 5x6g by Molmil](/molmil-images/mine/5x6g) | Crystal Structure of SMAD5-MH1/palindromic SBE DNA complex | Descriptor: | DNA (5'-D(P*AP*TP*CP*AP*GP*TP*CP*TP*AP*GP*AP*CP*AP*TP*A)-3'), DNA (5'-D(P*GP*TP*AP*TP*GP*TP*CP*TP*AP*GP*AP*CP*TP*GP*A)-3'), Mothers against decapentaplegic homolog 5, ... | Authors: | Chai, N, Wang, J, Wang, Z.X, Wu, J.W. | Deposit date: | 2017-02-21 | Release date: | 2017-03-15 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3.05 Å) | Cite: | Structural basis for the Smad5 MH1 domain to recognize different DNA sequences. Nucleic Acids Res., 43, 2015
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4GXL
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![BU of 4gxl by Molmil](/molmil-images/mine/4gxl) | The crystal structure of Galectin-8 C-CRD in complex with NDP52 | Descriptor: | GLYCEROL, Galectin-8, Peptide from Calcium-binding and coiled-coil domain-containing protein 2 | Authors: | Li, S, Wandel, M.P, Li, F, Liu, Z, He, C, Wu, J, Shi, Y, Randow, F. | Deposit date: | 2012-09-04 | Release date: | 2013-05-08 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.023 Å) | Cite: | Sterical hindrance promotes selectivity of the autophagy cargo receptor NDP52 for the danger receptor galectin-8 in antibacterial autophagy Sci.Signal., 6, 2013
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5X6H
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![BU of 5x6h by Molmil](/molmil-images/mine/5x6h) | Crystal Structure of SMAD5-MH1/GC-BRE DNA complex | Descriptor: | DNA (5'-D(P*GP*TP*AP*TP*GP*GP*CP*GP*CP*CP*AP*TP*AP*C)-3'), Mothers against decapentaplegic homolog 5, ZINC ION | Authors: | Chai, N, Wang, J, Wang, Z.X, Wu, J.W. | Deposit date: | 2017-02-22 | Release date: | 2017-03-15 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Structural basis for the Smad5 MH1 domain to recognize different DNA sequences. Nucleic Acids Res., 43, 2015
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4ZJS
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![BU of 4zjs by Molmil](/molmil-images/mine/4zjs) | Crystal structure of a chimeric acetylcholine binding protein from Aplysia Californica (Ac-AChBP) containing the main immunogenic region (MIR) from the human alpha 1 subunit of the muscle nicotinic acetylcholine receptor in complex with anatoxin-A. | Descriptor: | 1-[(1R,6R)-9-azabicyclo[4.2.1]non-2-en-2-yl]ethanone, Acetylcholine receptor subunit alpha,Soluble acetylcholine receptor,Acetylcholine receptor subunit alpha,Soluble acetylcholine receptor | Authors: | Talley, T.T, Bobango, J, Wu, J, Park, J.F, Luo, J, Lindsatrom, J, Taylor, P. | Deposit date: | 2015-04-29 | Release date: | 2015-05-13 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.2301 Å) | Cite: | Main immunogenic region structure promotes binding of conformation-dependent myasthenia gravis autoantibodies, nicotinic acetylcholine receptor conformation maturation, and agonist sensitivity. J. Neurosci., 29, 2009
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3TG1
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![BU of 3tg1 by Molmil](/molmil-images/mine/3tg1) | |
5YKF
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![BU of 5ykf by Molmil](/molmil-images/mine/5ykf) | |
5YKG
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![BU of 5ykg by Molmil](/molmil-images/mine/5ykg) | |
5YKE
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![BU of 5yke by Molmil](/molmil-images/mine/5yke) | |
7XBR
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![BU of 7xbr by Molmil](/molmil-images/mine/7xbr) | Crystal structure of phosphorylated AtMKK5 | Descriptor: | Mitogen-activated protein kinase kinase 5 | Authors: | Pei, C.J, Luo, Z.P, Wu, J.W, Wang, Z.X. | Deposit date: | 2022-03-22 | Release date: | 2023-02-08 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Crystal structure of the phosphorylated Arabidopsis MKK5 reveals activation mechanism of MAPK kinases. Acta Biochim.Biophys.Sin., 54, 2022
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5Y0U
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![BU of 5y0u by Molmil](/molmil-images/mine/5y0u) | The solution structure of AEBP2 C2H2 zinc fingers | Descriptor: | ZINC ION, Zinc finger protein AEBP2 | Authors: | Sun, A, Shi, Y, Wu, J. | Deposit date: | 2017-07-18 | Release date: | 2018-08-01 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Structural and biochemical insights into human zinc finger protein AEBP2 reveals interactions with RBBP4. Protein Cell, 9, 2018
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5YW9
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![BU of 5yw9 by Molmil](/molmil-images/mine/5yw9) | |
5YWB
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![BU of 5ywb by Molmil](/molmil-images/mine/5ywb) | |
5YWC
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![BU of 5ywc by Molmil](/molmil-images/mine/5ywc) | |
5YW8
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![BU of 5yw8 by Molmil](/molmil-images/mine/5yw8) | |
5WZH
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![BU of 5wzh by Molmil](/molmil-images/mine/5wzh) | Structure of APUM23-GGAAUUGACGG | Descriptor: | Pumilio homolog 23, RNA (5'-R(*GP*GP*AP*AP*UP*UP*GP*AP*CP*GP*G)-3') | Authors: | Bao, H, Wang, N, Wang, C, Jiang, Y, Wu, J, Shi, Y. | Deposit date: | 2017-01-18 | Release date: | 2017-09-27 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.509 Å) | Cite: | Structural basis for the specific recognition of 18S rRNA by APUM23. Nucleic Acids Res., 45, 2017
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5WZI
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![BU of 5wzi by Molmil](/molmil-images/mine/5wzi) | Structure of APUM23-GGAGUUGACGG | Descriptor: | Pumilio homolog 23, RNA (5'-R(*GP*GP*AP*GP*UP*UP*GP*AP*CP*GP*G)-3') | Authors: | Bao, H, Wang, N, Wang, C, Jiang, Y, Wu, J, Shi, Y. | Deposit date: | 2017-01-18 | Release date: | 2017-09-27 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Structural basis for the specific recognition of 18S rRNA by APUM23. Nucleic Acids Res., 45, 2017
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5YWA
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![BU of 5ywa by Molmil](/molmil-images/mine/5ywa) | |