4GXL

The crystal structure of Galectin-8 C-CRD in complex with NDP52

Summary for 4GXL

Entry DOI	10.2210/pdb4gxl/pdb
Descriptor	Galectin-8, Peptide from Calcium-binding and coiled-coil domain-containing protein 2, GLYCEROL, ... (4 entities in total)
Functional Keywords	protein-protein interaction, carbohydrate recognition, ndp52, protein binding
Biological source	Homo sapiens (human) More
Cellular location	Cytoplasmic vesicle : O00214 Cytoplasm, perinuclear region : Q13137
Total number of polymer chains	2
Total formula weight	19225.69
Authors	Li, S.,Wandel, M.P.,Li, F.,Liu, Z.,He, C.,Wu, J.,Shi, Y.,Randow, F. (deposition date: 2012-09-04, release date: 2013-05-08, Last modification date: 2024-03-20)
Primary citation	Li, S.,Wandel, M.P.,Li, F.,Liu, Z.,He, C.,Wu, J.,Shi, Y.,Randow, F. Sterical hindrance promotes selectivity of the autophagy cargo receptor NDP52 for the danger receptor galectin-8 in antibacterial autophagy Sci.Signal., 6:ra9-ra9, 2013 Cited by PubMed: 23386746 DOI: 10.1126/scisignal.2003730 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.023 Å)

Structure validation