4GXL

The crystal structure of Galectin-8 C-CRD in complex with NDP52

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Galectin-8	polymer	153	17532.9	1	UniProt (O00214) Pfam (PF00337) In PDB	Homo sapiens (human)	Gal-8, Po66 carbohydrate-binding protein, Po66-CBP, Prostate carcinoma tumor antigen 1, PCTA-1
2	B	Peptide from Calcium-binding and coiled-coil domain-containing protein 2	polymer	14	1508.6	1	UniProt (Q13137) In PDB	Homo sapiens	Antigen nuclear dot 52 kDa protein, Nuclear domain 10 protein NDP52, Nuclear domain 10 protein 52, Nuclear dot protein 52
3	A	GLYCEROL	non-polymer		92.1	2	Chemie (GOL)
4		water	water		18.0	119	Chemie (HOH)

Sequence modifications

A: 228 - 359 (UniProt: O00214)

PDB	External Database	Details
Met 207	-	expression tag
Gly 208	-	expression tag
Ser 209	-	expression tag
Ser 210	-	expression tag
His 211	-	expression tag
His 212	-	expression tag
His 213	-	expression tag
His 214	-	expression tag
His 215	-	expression tag
His 216	-	expression tag
Ser 217	-	expression tag
Ser 218	-	expression tag
Gly 219	-	expression tag
Glu 220	-	expression tag
Asn 221	-	expression tag
Leu 222	-	expression tag
Tyr 223	-	expression tag
Phe 224	-	expression tag
Gln 225	-	expression tag
His 226	-	expression tag
Met 227	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	19041.5
Non-Polymers*	Number of molecules	2
	Total formula weight	184.2
All*	Total formula weight	19225.7

*Water molecules are not included.