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PDB: 34 results

1W8A
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Third LRR domain of Drosophila Slit
Descriptor: SLIT PROTEIN
Authors:Howitt, J.A, Clout, N.J, Hohenester, E.
Deposit date:2004-09-17
Release date:2004-10-25
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Binding Site for Robo Receptors Revealed by Dissection of the Leucine-Rich Repeat Region of Slit.
Embo J., 23, 2004
1P69
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STRUCTURAL BASIS FOR VARIATION IN ADENOVIRUS AFFINITY FOR THE CELLULAR RECEPTOR CAR (P417S MUTANT)
Descriptor: Coxsackievirus and adenovirus receptor, Fiber protein
Authors:Howitt, J, Bewley, M.C, Graziano, V, Flanagan, J.M, Freimuth, P.
Deposit date:2003-04-29
Release date:2004-05-11
Last modified:2018-08-22
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structural basis for variation in adenovirus affinity for the cellular coxsackievirus and adenovirus receptor.
J.Biol.Chem., 278, 2003
1P6A
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STRUCTURAL BASIS FOR VARIATION IN ADENOVIRUS AFFINITY FOR THE CELLULAR RECEPTOR CAR (S489Y MUTANT)
Descriptor: Coxsackievirus and adenovirus receptor, Fiber protein
Authors:Howitt, J, Bewley, M.C, Graziano, V, Flanagan, J.M, Freimuth, P.
Deposit date:2003-04-29
Release date:2004-05-11
Last modified:2018-08-22
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural basis for variation in adenovirus affinity for the cellular coxsackievirus and adenovirus receptor.
J.Biol.Chem., 278, 2003
1S8F
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Crystal structure of Rab9 complexed to GDP reveals a dimer with an active conformation of switch II
Descriptor: BENZOIC ACID, CHLORIDE ION, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Wittmann, J.G, Rudolph, M.G.
Deposit date:2004-02-02
Release date:2004-06-11
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:Crystal structure of Rab9 complexed to GDP reveals a dimer with an active conformation of switch II.
Febs Lett., 568, 2004
2QCH
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Crystal structure of the orotidine-5'-monophosphate decarboxylase domain of human UMP synthase bound to 5-iodo-UMP
Descriptor: 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, 5-IODO-2'-DEOXYURIDINE-5'-MONOPHOSPHATE, IODIDE ION, ...
Authors:Wittmann, J, Rudolph, M.
Deposit date:2007-06-19
Release date:2007-11-06
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structures of the human orotidine-5'-monophosphate decarboxylase support a covalent mechanism and provide a framework for drug design.
Structure, 16, 2008
2QCF
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Crystal structure of the orotidine-5'-monophosphate decarboxylase domain (Asp312Asn mutant) of human UMP synthase bound to 5-fluoro-UMP
Descriptor: 5-FLUORO-URIDINE-5'-MONOPHOSPHATE, GLYCEROL, Uridine 5'-monophosphate synthase (UMP synthase)
Authors:Wittmann, J, Rudolph, M.
Deposit date:2007-06-19
Release date:2007-11-06
Last modified:2021-10-20
Method:X-RAY DIFFRACTION (1.22 Å)
Cite:Structures of the human orotidine-5'-monophosphate decarboxylase support a covalent mechanism and provide a framework for drug design.
Structure, 16, 2008
2QCE
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Crystal structure of the orotidine-5'-monophosphate decarboxylase domain of human UMP synthase bound to sulfate, glycerol, and chloride
Descriptor: CHLORIDE ION, GLYCEROL, SULFATE ION, ...
Authors:Wittmann, J, Rudolph, M.
Deposit date:2007-06-19
Release date:2007-11-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.43 Å)
Cite:Structures of the human orotidine-5'-monophosphate decarboxylase support a covalent mechanism and provide a framework for drug design.
Structure, 16, 2008
2QCL
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Crystal structure of the orotidine-5'-monophosphate decarboxylase domain (Asp312Asn mutant) of human UMP synthase bound to OMP
Descriptor: GLYCEROL, OROTIDINE-5'-MONOPHOSPHATE, Uridine 5'-monophosphate synthase (UMP synthase)
Authors:Wittmann, J, Rudolph, M.
Deposit date:2007-06-19
Release date:2007-11-06
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structures of the human orotidine-5'-monophosphate decarboxylase support a covalent mechanism and provide a framework for drug design.
Structure, 16, 2008
2QCC
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Crystal structure of the orotidine-5'-monophosphate decarboxylase domain of human UMP synthase, apo form
Descriptor: GLYCEROL, Orotidine 5'- phosphate decarboxylase (OMPdecase), SULFATE ION
Authors:Wittmann, J, Rudolph, M.
Deposit date:2007-06-19
Release date:2007-11-06
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structures of the human orotidine-5'-monophosphate decarboxylase support a covalent mechanism and provide a framework for drug design.
Structure, 16, 2008
2QCM
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Crystal structure of the orotidine-5'-monophosphate decarboxylase domain (Asp312Asn mutant) of human UMP synthase bound to 6-hydroxymethyl-UMP
Descriptor: 6-(HYDROXYMETHYL)URIDINE 5'-(DIHYDROGEN PHOSPHATE), Uridine 5'-monophosphate synthase (UMP synthase)
Authors:Wittmann, J, Rudolph, M.
Deposit date:2007-06-19
Release date:2007-11-06
Last modified:2021-10-20
Method:X-RAY DIFFRACTION (1.67 Å)
Cite:Structures of the human orotidine-5'-monophosphate decarboxylase support a covalent mechanism and provide a framework for drug design.
Structure, 16, 2008
2QCG
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Crystal structure of the orotidine-5'-monophosphate decarboxylase domain of human UMP synthase bound to 5-bromo-UMP
Descriptor: 5-BROMO-URIDINE-5'-MONOPHOSPHATE, Uridine 5'-monophosphate synthase (UMP synthase)
Authors:Wittmann, J, Rudolph, M.
Deposit date:2007-06-19
Release date:2007-11-06
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structures of the human orotidine-5'-monophosphate decarboxylase support a covalent mechanism and provide a framework for drug design.
Structure, 16, 2008
2QCN
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Covalent complex of the orotidine-5'-monophosphate decarboxylase domain of human UMP synthase with 6-iodo-UMP
Descriptor: GLYCEROL, SULFATE ION, URIDINE-5'-MONOPHOSPHATE, ...
Authors:Wittmann, J, Rudolph, M.
Deposit date:2007-06-19
Release date:2007-11-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structures of the human orotidine-5'-monophosphate decarboxylase support a covalent mechanism and provide a framework for drug design.
Structure, 16, 2008
2QCD
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BU of 2qcd by Molmil
Crystal structure of the orotidine-5'-monophosphate decarboxylase domain of human UMP synthase bound to UMP
Descriptor: URIDINE-5'-MONOPHOSPHATE, Uridine 5'-monophosphate synthase (UMP synthase)
Authors:Wittmann, J, Rudolph, M.
Deposit date:2007-06-19
Release date:2007-11-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:Structures of the human orotidine-5'-monophosphate decarboxylase support a covalent mechanism and provide a framework for drug design.
Structure, 16, 2008
5MV1
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Crystal structure of the E protein of the Japanese encephalitis virulent virus
Descriptor: E protein
Authors:Liu, X, Zhao, X, Na, R, Li, L, Warkentin, E, Witt, J, Lu, X, Wei, Y, Peng, G, Li, Y, Wang, J.
Deposit date:2017-01-14
Release date:2018-05-23
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:The structure differences of Japanese encephalitis virus SA14 and SA14-14-2 E proteins elucidate the virulence attenuation mechanism.
Protein Cell, 10, 2019
5MV2
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Crystal structure of the E protein of the Japanese encephalitis live attenuated vaccine virus
Descriptor: E protein
Authors:Liu, X, Zhao, X, Na, R, Li, L, Warkentin, E, Witt, J, Lu, X, Wei, Y, Peng, G, Li, Y, Wang, J.
Deposit date:2017-01-14
Release date:2018-05-23
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The structure differences of Japanese encephalitis virus SA14 and SA14-14-2 E proteins elucidate the virulence attenuation mechanism.
Protein Cell, 10, 2019
1HYO
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CRYSTAL STRUCTURE OF FUMARYLACETOACETATE HYDROLASE COMPLEXED WITH 4-(HYDROXYMETHYLPHOSPHINOYL)-3-OXO-BUTANOIC ACID
Descriptor: 4-[HYDROXY-[METHYL-PHOSPHINOYL]]-3-OXO-BUTANOIC ACID, ACETATE ION, CALCIUM ION, ...
Authors:Bateman, R.L, Bhanumoorthy, P, Witte, J.F, McClard, R.W, Grompe, M, Timm, D.E.
Deposit date:2001-01-21
Release date:2001-02-14
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Mechanistic inferences from the crystal structure of fumarylacetoacetate hydrolase with a bound phosphorus-based inhibitor.
J.Biol.Chem., 276, 2001
1C7Z
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BU of 1c7z by Molmil
REGULATORY COMPLEX OF FRUCTOSE-2,6-BISPHOSPHATASE
Descriptor: FRUCTOSE-2,6-BISPHOSPHATASE, GLYCERALDEHYDE-3-PHOSPHATE, PHOSPHATE ION
Authors:Lee, Y.H, Olson, T.W, McClard, R.W, Witte, J.F, McFarlan, S.C, Banaszak, L.J, Levitt, D.G, Lange, A.J.
Deposit date:2000-04-03
Release date:2003-06-10
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Reaction Mechanism of Fructose-2,6-bisphosphatase Suggested by the Crystal Structures of a pseudo-Michaelis complex and Metabolite Complexes
To be Published
1C81
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MICHAELIS COMPLEX OF FRUCTOSE-2,6-BISPHOSPHATASE
Descriptor: 2,5-anhydro-1-deoxy-1-phosphono-6-O-phosphono-D-glucitol, FRUCTOSE-2,6-BISPHOSPHATASE
Authors:Lee, Y.H, Olson, T.W, McClard, R.W, Witte, J.F, McFarlan, S.C, Banaszak, L.J, Levitt, D.G, Lange, A.J.
Deposit date:2000-04-03
Release date:2003-06-10
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Reaction Mechanism of Fructose-2,6-bisphosphatase Suggested by the Crystal Structures of a pseudo-Michaelis complex and Metabolite Complexes
To be Published
1C80
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REGULATORY COMPLEX OF FRUCTOSE-2,6-BISPHOSPHATASE
Descriptor: FRUCTOSE-2,6-BISPHOSPHATASE, GUANOSINE-5'-TRIPHOSPHATE, PHOSPHATE ION
Authors:Lee, Y.H, Olson, T.W, McClard, R.W, Witte, J.F, McFarlan, S.C, Banaszak, L.J, Levitt, D.G, Lange, A.J.
Deposit date:2000-04-03
Release date:2003-06-10
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Reaction Mechanism of Fructose-2,6-bisphosphatase Suggested by the Crystal Structures of a pseudo-Michaelis complex and Metabolite Complexes
To be Published
2XYK
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BU of 2xyk by Molmil
Group II 2-on-2 Hemoglobin from the Plant Pathogen Agrobacterium tumefaciens
Descriptor: 2-ON-2 HEMOGLOBIN, PROTOPORPHYRIN IX CONTAINING FE
Authors:Pesce, A, Nardini, M, LaBarre, M, Richard, C, Wittenberg, J.B, Wittenberg, B.A, Guertin, M, Bolognesi, M.
Deposit date:2010-11-18
Release date:2010-12-01
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural Characterization of a Group II 2/2 Hemoglobin from the Plant Pathogen Agrobacterium Tumefaciens.
Biochim.Biophys.Acta, 1814, 2011
2K9R
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Enhancing the activity of insulin by stereospecific unfolding
Descriptor: Insulin
Authors:Hua, Q.X, Xu, B, Huang, K, Hu, S.Q, Nakarawa, S, Jia, W.H, Philips, N.F.P, Wittaker, L, Wittaker, J, Katsoyannis, P.G, Weiss, M.A.
Deposit date:2008-10-23
Release date:2008-11-11
Last modified:2021-10-20
Method:SOLUTION NMR
Cite:Enhancing the Activity of a Protein by Stereospecific Unfolding: CONFORMATIONAL LIFE CYCLE OF INSULIN AND ITS EVOLUTIONARY ORIGINS.
J.Biol.Chem., 284, 2009
2K91
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Enhancing the activity of insulin by stereospecific unfolding
Descriptor: Insulin
Authors:Hua, Q.X, Xu, B, Huang, K, Hu, S.Q, Nakarawa, S, Jia, W.H, Philips, N.F.P, Wittaker, L, Wittaker, J, Katsoyannis, P.G, Weiss, M.A.
Deposit date:2008-09-29
Release date:2008-11-18
Last modified:2021-10-20
Method:SOLUTION NMR
Cite:Enhancing the Activity of a Protein by Stereospecific Unfolding: CONFORMATIONAL LIFE CYCLE OF INSULIN AND ITS EVOLUTIONARY ORIGINS.
J.Biol.Chem., 284, 2009
1FLP
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BU of 1flp by Molmil
STRUCTURE OF THE SULFIDE-REACTIVE HEMOGLOBIN FROM THE CLAM LUCINA PECTINATA: CRYSTALLOGRAPHIC ANALYSIS AT 1.5 ANGSTROMS RESOLUTION
Descriptor: HEMOGLOBIN I (AQUO MET), PROTOPORPHYRIN IX CONTAINING FE
Authors:Rizzi, M, Wittenberg, J.B, Ascenzi, P, Fasano, M, Coda, A, Bolognesi, M.
Deposit date:1994-05-16
Release date:1994-07-31
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structure of the sulfide-reactive hemoglobin from the clam Lucina pectinata. Crystallographic analysis at 1.5 A resolution.
J.Mol.Biol., 244, 1994
1OS8
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RECOMBINANT STREPTOMYCES GRISEUS TRYPSIN
Descriptor: CALCIUM ION, SULFATE ION, trypsin
Authors:Page, M.J, Wong, S.L, Hewitt, J, Strynadka, N.C, MacGillivray, R.T.
Deposit date:2003-03-18
Release date:2003-08-19
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Engineering the Primary Substrate Specificity of Streptomyces griseus Trypsin.
Biochemistry, 42, 2003
2VRA
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Drosophila Robo IG1-2 (monoclinic form)
Descriptor: 2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose, ROUNDABOUT 1, SULFATE ION
Authors:Fukuhara, N, Howitt, J.A, Hussain, S, Hohenester, E.
Deposit date:2008-03-28
Release date:2008-04-08
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural and Functional Analysis of Slit and Heparin Binding to Immunoglobulin-Like Domains 1 and 2 of Drosophila Robo
J.Biol.Chem., 283, 2008

 

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