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1HYO

CRYSTAL STRUCTURE OF FUMARYLACETOACETATE HYDROLASE COMPLEXED WITH 4-(HYDROXYMETHYLPHOSPHINOYL)-3-OXO-BUTANOIC ACID

Summary for 1HYO
Entry DOI10.2210/pdb1hyo/pdb
Related1QCN 1QCO 1QQJ
DescriptorFUMARYLACETOACETATE HYDROLASE, MAGNESIUM ION, CALCIUM ION, ... (7 entities in total)
Functional Keywordsbeta-sandwich roll, hydrolase
Biological sourceMus musculus (house mouse)
Total number of polymer chains2
Total formula weight93259.06
Authors
Bateman, R.L.,Bhanumoorthy, P.,Witte, J.F.,McClard, R.W.,Grompe, M.,Timm, D.E. (deposition date: 2001-01-21, release date: 2001-02-14, Last modification date: 2023-08-09)
Primary citationBateman, R.L.,Bhanumoorthy, P.,Witte, J.F.,McClard, R.W.,Grompe, M.,Timm, D.E.
Mechanistic inferences from the crystal structure of fumarylacetoacetate hydrolase with a bound phosphorus-based inhibitor.
J.Biol.Chem., 276:15284-15291, 2001
Cited by
PubMed: 11154690
DOI: 10.1074/jbc.M007621200
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.3 Å)
Structure validation

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