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1HYO

CRYSTAL STRUCTURE OF FUMARYLACETOACETATE HYDROLASE COMPLEXED WITH 4-(HYDROXYMETHYLPHOSPHINOYL)-3-OXO-BUTANOIC ACID

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
FUMARYLACETOACETATE HYDROLASEpolymer42146296.72UniProt (P35505)
Pfam (PF09298)
Pfam (PF01557)
Mus musculus (house mouse)FUMARYLACETOACETASE, BETA-DIKETONASE, FAA
2C, G
(A, B)
MAGNESIUM IONnon-polymer24.32Chemie (MG)
3D, H
(A, B)
CALCIUM IONnon-polymer40.12Chemie (CA)
4E, J
(A, B)
ACETATE IONnon-polymer59.02Chemie (ACT)
5F, K
(A, B)
4-[HYDROXY-[METHYL-PHOSPHINOYL]]-3-OXO-BUTANOIC ACIDnon-polymer180.12Chemie (HBU)
6I
(B)
NICKEL (II) IONnon-polymer58.71Chemie (NI)
7L, M
(A, B)
waterwater18.0834Chemie (HOH)
Sequence modifications
A, B: 1 - 419 (UniProt: P35505)
PDBExternal DatabaseDetails
Gly -1-cloning artifact
Ser 0-cloning artifact
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight92593.3
Non-Polymers*Number of molecules9
Total formula weight665.7
All*Total formula weight93259.1
*Water molecules are not included.

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PDB entries from 2025-07-02

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