1UPT
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![BU of 1upt by Molmil](/molmil-images/mine/1upt) | Structure of a complex of the golgin-245 GRIP domain with Arl1 | 分子名称: | ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 1, GOLGI AUTOANTIGEN, GOLGIN SUBFAMILY A MEMBER 4, ... | 著者 | Panic, B, Perisic, O, Veprintsev, D.B, Williams, R.L, Munro, S. | 登録日 | 2003-10-12 | 公開日 | 2003-10-30 | 最終更新日 | 2019-10-23 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Structural Basis for Arl1-Dependent Targeting of Homodimeric Grip Domains to the Golgi Apparatus Mol.Cell, 12, 2003
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1W2D
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![BU of 1w2d by Molmil](/molmil-images/mine/1w2d) | Human Inositol (1,4,5)-trisphosphate 3-kinase complexed with Mn2+/ADP/Ins(1,3,4,5)P4 | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, INOSITOL-(1,3,4,5)-TETRAKISPHOSPHATE, INOSITOL-TRISPHOSPHATE 3-KINASE A, ... | 著者 | Gonzalez, B, Schell, M.J, Irvine, R.F, Williams, R.L. | 登録日 | 2004-07-01 | 公開日 | 2004-09-09 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | 主引用文献 | Structure of a Human Inositol 1,4,5-Trisphosphate 3-Kinase; Substrate Binding Reveals Why It is not a Phosphoinositide 3-Kinase Mol.Cell, 15, 2004
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2XVC
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![BU of 2xvc by Molmil](/molmil-images/mine/2xvc) | Molecular and structural basis of ESCRT-III recruitment to membranes during archaeal cell division | 分子名称: | CADMIUM ION, CDVA, SSO0911, ... | 著者 | Samson, R.Y, Obita, T, Hodgson, B, Shaw, M.K, Chong, P.L, Williams, R.L, Bell, S.D. | 登録日 | 2010-10-25 | 公開日 | 2011-02-02 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Molecular and Structural Basis of Escrt-III Recruitment to Membranes During Archaeal Cell Division. Mol.Cell, 41, 2011
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6CVO
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![BU of 6cvo by Molmil](/molmil-images/mine/6cvo) | Human Aprataxin (Aptx) bound to nicked RNA-DNA, AMP and Zn product complex | 分子名称: | ADENOSINE MONOPHOSPHATE, Aprataxin, BETA-MERCAPTOETHANOL, ... | 著者 | Schellenberg, M.J, Tumbale, P.P, Williams, R.S. | 登録日 | 2018-03-28 | 公開日 | 2018-08-29 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Mechanism of APTX nicked DNA sensing and pleiotropic inactivation in neurodegenerative disease. EMBO J., 37, 2018
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2PT7
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![BU of 2pt7 by Molmil](/molmil-images/mine/2pt7) | Crystal structure of Cag VirB11 (HP0525) and an inhibitory protein (HP1451) | 分子名称: | Cag-alfa, Hypothetical protein | 著者 | Hare, S, Fischer, W, Williams, R, Terradot, L, Bayliss, R, Haas, R, Waksman, G. | 登録日 | 2007-05-08 | 公開日 | 2007-11-13 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Identification, structure and mode of action of a new regulator of the Helicobacter pylori HP0525 ATPase. Embo J., 26, 2007
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8OXP
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![BU of 8oxp by Molmil](/molmil-images/mine/8oxp) | ATM(Q2971A) in complex with Mg AMP-PNP | 分子名称: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Serine-protein kinase ATM, ... | 著者 | Howes, A.C, Perisic, O, Williams, R.L. | 登録日 | 2023-05-02 | 公開日 | 2023-09-27 | 最終更新日 | 2023-10-11 | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | 主引用文献 | Structural insights into the activation of ataxia-telangiectasia mutated by oxidative stress. Sci Adv, 9, 2023
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8OXQ
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![BU of 8oxq by Molmil](/molmil-images/mine/8oxq) | ATM(Q2971A) dimeric C-terminal region in complex with Mg AMP-PNP | 分子名称: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Serine-protein kinase ATM, ... | 著者 | Howes, A.C, Perisic, O, Williams, R.L. | 登録日 | 2023-05-02 | 公開日 | 2023-09-27 | 最終更新日 | 2023-10-11 | 実験手法 | ELECTRON MICROSCOPY (2.5 Å) | 主引用文献 | Structural insights into the activation of ataxia-telangiectasia mutated by oxidative stress. Sci Adv, 9, 2023
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8OXM
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![BU of 8oxm by Molmil](/molmil-images/mine/8oxm) | ATM(Q2971A) activated by oxidative stress in complex with Mg AMP-PNP and p53 peptide | 分子名称: | Cellular tumor antigen p53, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | 著者 | Howes, A.C, Perisic, O, Williams, R.L. | 登録日 | 2023-05-02 | 公開日 | 2023-09-27 | 最終更新日 | 2023-10-11 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Structural insights into the activation of ataxia-telangiectasia mutated by oxidative stress. Sci Adv, 9, 2023
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8OXO
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![BU of 8oxo by Molmil](/molmil-images/mine/8oxo) | ATM(Q2971A) dimeric C-terminal region activated by oxidative stress in complex with Mg AMP-PNP and p53 peptide | 分子名称: | Cellular tumor antigen p53, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | 著者 | Howes, A.C, Perisic, O, Williams, R.L. | 登録日 | 2023-05-02 | 公開日 | 2023-09-27 | 最終更新日 | 2023-10-11 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Structural insights into the activation of ataxia-telangiectasia mutated by oxidative stress. Sci Adv, 9, 2023
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6SB2
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![BU of 6sb2 by Molmil](/molmil-images/mine/6sb2) | cryo-EM structure of mTORC1 bound to active RagA/C GTPases | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Ras-related GTP-binding protein A, ... | 著者 | Anandapadamanaban, M, Berndt, A, Masson, G.R, Perisic, O, Williams, R.L. | 登録日 | 2019-07-18 | 公開日 | 2019-10-16 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (6.2 Å) | 主引用文献 | Architecture of human Rag GTPase heterodimers and their complex with mTORC1. Science, 366, 2019
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6S8F
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![BU of 6s8f by Molmil](/molmil-images/mine/6s8f) | Structure of nucleotide-bound Tel1/ATM | 分子名称: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Serine/threonine-protein kinase TEL1,Serine/threonine-protein kinase TEL1,Serine/threonine-protein kinase TEL1,Serine/threonine-protein kinase TEL1,Serine/threonine-protein kinase TEL1 | 著者 | Yates, L.A, Williams, R.M, Ayala, R, Zhang, X. | 登録日 | 2019-07-09 | 公開日 | 2019-10-30 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Cryo-EM Structure of Nucleotide-Bound Tel1ATMUnravels the Molecular Basis of Inhibition and Structural Rationale for Disease-Associated Mutations. Structure, 28, 2020
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5W7P
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![BU of 5w7p by Molmil](/molmil-images/mine/5w7p) | Crystal structure of OxaC | 分子名称: | OxaC, S-ADENOSYLMETHIONINE | 著者 | Newmister, S.A, Romminger, S, Schmidt, J.J, Williams, R.M, Smith, J.L, Berlinck, R.G.S, Sherman, D.H. | 登録日 | 2017-06-20 | 公開日 | 2018-06-27 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Unveiling sequential late-stage methyltransferase reactions in the meleagrin/oxaline biosynthetic pathway. Org. Biomol. Chem., 16, 2018
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2DOQ
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![BU of 2doq by Molmil](/molmil-images/mine/2doq) | crystal structure of Sfi1p/Cdc31p complex | 分子名称: | CALCIUM ION, Cell division control protein 31, SFI1p | 著者 | Li, S, Sandercock, A.M, Conduit, P.T, Robinson, C.V, Williams, R.L, Kilmartin, J.V. | 登録日 | 2006-05-03 | 公開日 | 2006-06-27 | 最終更新日 | 2017-10-11 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structural role of Sfi1p-centrin filaments in budding yeast spindle pole body duplication. J.Cell Biol., 173, 2006
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5W7K
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![BU of 5w7k by Molmil](/molmil-images/mine/5w7k) | Crystal structure of OxaG | 分子名称: | CHLORIDE ION, OxaG, S-ADENOSYL-L-HOMOCYSTEINE | 著者 | Newmister, S.A, Romminger, S, Schmidt, J.J, Williams, R.M, Smith, J.L, Berlinck, R.G.S, Sherman, D.H. | 登録日 | 2017-06-20 | 公開日 | 2018-06-27 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.994 Å) | 主引用文献 | Unveiling sequential late-stage methyltransferase reactions in the meleagrin/oxaline biosynthetic pathway. Org. Biomol. Chem., 16, 2018
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5W7S
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![BU of 5w7s by Molmil](/molmil-images/mine/5w7s) | Crystal structure of OxaC in complex with sinefungin and meleagrin | 分子名称: | (3E,7aR,12aS)-6-hydroxy-3-[(1H-imidazol-4-yl)methylidene]-12-methoxy-7a-(2-methylbut-3-en-2-yl)-7a,12-dihydro-1H,5H-imidazo[1',2':1,2]pyrido[2,3-b]indole-2,5(3H)-dione, OxaC, SINEFUNGIN | 著者 | Newmister, S.A, Romminger, S, Schmidt, J.J, Williams, R.M, Smith, J.L, Berlinck, R.G.S, Sherman, D.H. | 登録日 | 2017-06-20 | 公開日 | 2018-06-27 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.948 Å) | 主引用文献 | Unveiling sequential late-stage methyltransferase reactions in the meleagrin/oxaline biosynthetic pathway. Org. Biomol. Chem., 16, 2018
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5W7R
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![BU of 5w7r by Molmil](/molmil-images/mine/5w7r) | Crystal structure of OxaC in complex with SAH and oxaline | 分子名称: | (3E,7aR,12aS)-3-[(1H-imidazol-4-yl)methylidene]-6,12-dimethoxy-7a-(2-methylbut-3-en-2-yl)-7a,12-dihydro-1H,5H-imidazo[1 ',2':1,2]pyrido[2,3-b]indole-2,5(3H)-dione, OxaC, S-ADENOSYL-L-HOMOCYSTEINE | 著者 | Newmister, S.A, Romminger, S, Schmidt, J.J, Williams, R.M, Smith, J.L, Berlinck, R.G.S, Sherman, D.H. | 登録日 | 2017-06-20 | 公開日 | 2018-07-04 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.497 Å) | 主引用文献 | Unveiling sequential late-stage methyltransferase reactions in the meleagrin/oxaline biosynthetic pathway. Org. Biomol. Chem., 16, 2018
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6CVP
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![BU of 6cvp by Molmil](/molmil-images/mine/6cvp) | Human Aprataxin (Aptx) R199H bound to RNA-DNA, AMP and Zn product complex | 分子名称: | ADENOSINE MONOPHOSPHATE, Aprataxin, DNA (5'-D(*GP*AP*AP*TP*CP*AP*TP*AP*AP*C)-3'), ... | 著者 | Schellenberg, M.J, Williams, R.S, Tumbale, P.S. | 登録日 | 2018-03-28 | 公開日 | 2018-07-04 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.999 Å) | 主引用文献 | Mechanism of APTX nicked DNA sensing and pleiotropic inactivation in neurodegenerative disease. EMBO J., 37, 2018
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5W7M
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![BU of 5w7m by Molmil](/molmil-images/mine/5w7m) | Crystal structure of RoqN | 分子名称: | Glandicoline B O-methyltransferase roqN, S-ADENOSYL-L-HOMOCYSTEINE | 著者 | Newmister, S.A, Romminger, S, Schmidt, J.J, Williams, R.M, Smith, J.L, Berlinck, R.G.S, Sherman, D.H. | 登録日 | 2017-06-20 | 公開日 | 2018-06-27 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Unveiling sequential late-stage methyltransferase reactions in the meleagrin/oxaline biosynthetic pathway. Org. Biomol. Chem., 16, 2018
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4A55
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![BU of 4a55 by Molmil](/molmil-images/mine/4a55) | Crystal structure of p110alpha in complex with iSH2 of p85alpha and the inhibitor PIK-108 | 分子名称: | PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT ALPHA, PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE 3-KINASE CATALYTIC SUBUNIT ALPHA ISOFORM, PIK-108 | 著者 | Hon, W.-C, Berndt, A, Williams, R.L. | 登録日 | 2011-10-24 | 公開日 | 2011-12-28 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | Regulation of Lipid Binding Underlies the Activation Mechanism of Class Ia Pi3-Kinases. Oncogene, 31, 2012
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6CVQ
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![BU of 6cvq by Molmil](/molmil-images/mine/6cvq) | Human Aprataxin (Aptx) H201Q bound to RNA-DNA, AMP and Zn product complex | 分子名称: | ADENOSINE MONOPHOSPHATE, Aprataxin, BETA-MERCAPTOETHANOL, ... | 著者 | Schellenberg, M.J, Tumbale, P.S, Williams, R.S. | 登録日 | 2018-03-28 | 公開日 | 2018-07-04 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Mechanism of APTX nicked DNA sensing and pleiotropic inactivation in neurodegenerative disease. EMBO J., 37, 2018
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2R1Z
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![BU of 2r1z by Molmil](/molmil-images/mine/2r1z) | |
5DFZ
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![BU of 5dfz by Molmil](/molmil-images/mine/5dfz) | Structure of Vps34 complex II from S. cerevisiae. | 分子名称: | Nanobody binding S. cerevisiae Vps34, Phosphatidylinositol 3-kinase VPS34, Putative N-terminal domain of S. cerevisiae Vps30, ... | 著者 | Rostislavleva, K, Soler, N, Ohashi, Y, Zhang, L, Williams, R.L. | 登録日 | 2015-08-27 | 公開日 | 2015-10-07 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (4.4 Å) | 主引用文献 | Structure and flexibility of the endosomal Vps34 complex reveals the basis of its function on membranes. Science, 350, 2015
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8BXR
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![BU of 8bxr by Molmil](/molmil-images/mine/8bxr) | |
6U9I
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![BU of 6u9i by Molmil](/molmil-images/mine/6u9i) | Crystal structure of BvnE pinacolase from Penicillium brevicompactum | 分子名称: | BvnE, DI(HYDROXYETHYL)ETHER, GLYCEROL | 著者 | Ye, Y, Du, L, Zhang, X, Newmister, S.A, McCauley, M, Alegre-Requena, J.V, Zhang, W, Mu, S, Minami, A, Fraley, A.E, Adrover-Castellano, M.L, Carney, N, Shende, V.V, Oikawa, H, Kato, H, Tsukamoto, S, Paton, R.S, Williams, R.M, Sherman, D.H, Li, S. | 登録日 | 2019-09-09 | 公開日 | 2020-09-09 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.777 Å) | 主引用文献 | Fungal-derived brevianamide assembly by a stereoselective semipinacolase. Nat Catal, 3, 2020
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6CVT
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![BU of 6cvt by Molmil](/molmil-images/mine/6cvt) | Human Aprataxin (Aptx) V263G bound to RNA-DNA, AMP and Zn product complex | 分子名称: | ADENOSINE MONOPHOSPHATE, Aprataxin, DNA (5'-D(*GP*AP*AP*TP*CP*AP*TP*AP*AP*C)-3'), ... | 著者 | Schellenberg, M.J, Tumbale, P.S, Williams, R.S. | 登録日 | 2018-03-28 | 公開日 | 2018-07-04 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.941 Å) | 主引用文献 | Mechanism of APTX nicked DNA sensing and pleiotropic inactivation in neurodegenerative disease. EMBO J., 37, 2018
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