8OXO
ATM(Q2971A) dimeric C-terminal region activated by oxidative stress in complex with Mg AMP-PNP and p53 peptide
Summary for 8OXO
| Entry DOI | 10.2210/pdb8oxo/pdb |
| EMDB information | 17266 |
| Descriptor | Cellular tumor antigen p53, Serine-protein kinase ATM, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... (5 entities in total) |
| Functional Keywords | kinase, ataxia-telangiectasia mutated, atm, p53, signaling protein |
| Biological source | Homo sapiens (human) More |
| Total number of polymer chains | 4 |
| Total formula weight | 733927.82 |
| Authors | Howes, A.C.,Perisic, O.,Williams, R.L. (deposition date: 2023-05-02, release date: 2023-09-27, Last modification date: 2023-10-11) |
| Primary citation | Howes, A.C.,Perisic, O.,Williams, R.L. Structural insights into the activation of ataxia-telangiectasia mutated by oxidative stress. Sci Adv, 9:eadi8291-eadi8291, 2023 Cited by PubMed: 37756394DOI: 10.1126/sciadv.adi8291 PDB entries with the same primary citation |
| Experimental method | ELECTRON MICROSCOPY (3 Å) |
Structure validation
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