5DFZ

Structure of Vps34 complex II from S. cerevisiae.

Summary for 5DFZ

Entry DOI	10.2210/pdb5dfz/pdb
Descriptor	Vacuolar protein sorting-associated protein 38, Phosphatidylinositol 3-kinase VPS34, Serine/threonine-protein kinase VPS15, ... (6 entities in total)
Functional Keywords	vps34, vps15, vps30, vps38, autophagy, vacuolar protein sorting, yeast, complex ii, pi3p, kinase, lipid, wd40, bara, c2, coiled-coil, heat, nanobody, transferase
Biological source	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) More
Cellular location	Golgi apparatus, trans-Golgi network membrane; Peripheral membrane protein: Q05919 P22543 Golgi apparatus, trans-Golgi network membrane; Lipid-anchor: P22219 Endosome membrane; Peripheral membrane protein: Q02948
Total number of polymer chains	6
Total formula weight	400489.65
Authors	Rostislavleva, K.,Soler, N.,Ohashi, Y.,Zhang, L.,Williams, R.L. (deposition date: 2015-08-27, release date: 2015-10-07, Last modification date: 2017-08-30)
Primary citation	Rostislavleva, K.,Soler, N.,Ohashi, Y.,Zhang, L.,Pardon, E.,Burke, J.E.,Masson, G.R.,Johnson, C.,Steyaert, J.,Ktistakis, N.T.,Williams, R.L. Structure and flexibility of the endosomal Vps34 complex reveals the basis of its function on membranes. Science, 350:aac7365-aac7365, 2015 Cited by PubMed: 26450213 DOI: 10.1126/science.aac7365 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (4.4 Å)

Structure validation