5DFZ
Structure of Vps34 complex II from S. cerevisiae.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Vacuolar protein sorting-associated protein 38 | polymer | 441 | 51072.9 | 1 | UniProt (Q05919) Pfam (PF17649) | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | |
| 2 | B (C) | Phosphatidylinositol 3-kinase VPS34 | polymer | 875 | 100973.1 | 1 | UniProt (P22543) Pfam (PF00792) Pfam (PF00613) Pfam (PF00454) | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | PtdIns-3-kinase VPS34,Carboxypeptidase Y-deficient protein 15,Vacuolar protein sorting-associated protein 34,Vacuolar protein-targeting protein 29 |
| 3 | C (B) | Serine/threonine-protein kinase VPS15 | polymer | 1460 | 167082.5 | 1 | UniProt (P22219) Pfam (PF00069) | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | Golgi-retention defective mutant protein 8,Vacuolar protein sorting-associated protein 15 |
| 4 | D (E) | Nanobody binding S. cerevisiae Vps34 | polymer | 124 | 13772.3 | 1 | Lama glama | ||
| 5 | E (D) | Vacuolar protein sorting-associated protein 30 | polymer | 559 | 63400.7 | 1 | UniProt (Q02948) Pfam (PF17675) Pfam (PF04111) | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | Autophagy-related protein 6 |
| 6 | F (G) | Putative N-terminal domain of S. cerevisiae Vps30 | polymer | 49 | 4188.2 | 1 | Saccharomyces cerevisiae (Baker's yeast) |
Sequence modifications
A: 1 - 439 (UniProt: Q05919)
C: 1 - 875 (UniProt: P22543)
B: 1 - 1454 (UniProt: P22219)
D: 1 - 557 (UniProt: Q02948)
| PDB | External Database | Details |
|---|---|---|
| Gly 440 | - | expression tag |
| Ser 441 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Ala 2 | Ser 2 | conflict |
| Gly 241 | Asp 241 | conflict |
| PDB | External Database | Details |
|---|---|---|
| - | Ser 559 | deletion |
| - | Met 560 | deletion |
| - | Asp 561 | deletion |
| - | Asn 562 | deletion |
| - | Asn 563 | deletion |
| - | Thr 564 | deletion |
| - | Glu 565 | deletion |
| - | Ile 566 | deletion |
| - | Met 567 | deletion |
| - | Glu 568 | deletion |
| Gly 1455 | - | expression tag |
| Ser 1456 | - | expression tag |
| Ser 1457 | - | expression tag |
| Arg 1458 | - | expression tag |
| Pro 1459 | - | expression tag |
| Thr 1460 | - | expression tag |
| Thr 1461 | - | expression tag |
| Ala 1462 | - | expression tag |
| Ser 1463 | - | expression tag |
| Glu 1464 | - | expression tag |
| Asn 1465 | - | expression tag |
| Leu 1466 | - | expression tag |
| Tyr 1467 | - | expression tag |
| Phe 1468 | - | expression tag |
| Gln 1469 | - | expression tag |
| Gly 1470 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Ile 77 | Lys 77 | conflict |
| Ala 467 | Thr 467 | conflict |
| His 549 | Tyr 549 | conflict |
| Gly 558 | - | expression tag |
| Ser 559 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 400489.6 | |
| All* | Total formula weight | 400489.6 |
