5GOU
 
 | | Structure of a 16-mer protein nanocage fabricated from its 24-mer analogue by subunit interface redesign | | 分子名称: | Ferritin heavy chain | | 著者 | Zhang, S, Zang, J, Wang, W, Wang, H, Zhao, G. | | 登録日 | 2016-07-29 | | 公開日 | 2017-02-22 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.91 Å) | | 主引用文献 | Conversion of the Native 24-mer Ferritin Nanocage into Its Non-Native 16-mer Analogue by Insertion of Extra Amino Acid Residues.
Angew. Chem. Int. Ed. Engl., 55, 2016
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3WX4
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3CLH
 | | Crystal structure of 3-dehydroquinate synthase (DHQS)from Helicobacter pylori | | 分子名称: | 3-dehydroquinate synthase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ZINC ION | | 著者 | Wang, W.C, Liu, J.S, Cheng, W.C, Wang, H.J, Chen, Y.C. | | 登録日 | 2008-03-19 | | 公開日 | 2009-03-24 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structure-based inhibitor discovery of Helicobacter pylori dehydroquinate synthase.
Biochem.Biophys.Res.Commun., 373, 2008
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3DD4
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3WUR
 | | Structure of DMP19 Complex with 18-crown-6 | | 分子名称: | 1,2-ETHANEDIOL, 1,4,7,10,13,16-HEXAOXACYCLOOCTADECANE, L(+)-TARTARIC ACID, ... | | 著者 | Lee, C.C, Wang, H.C, Wang, A.H.J. | | 登録日 | 2014-05-02 | | 公開日 | 2014-10-15 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | | 主引用文献 | Crowning proteins: modulating the protein surface properties using crown ethers.
Angew.Chem.Int.Ed.Engl., 53, 2014
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5H64
 | | Cryo-EM structure of mTORC1 | | 分子名称: | Regulatory-associated protein of mTOR, Serine/threonine-protein kinase mTOR, Target of rapamycin complex subunit LST8 | | 著者 | Yang, H, Wang, J, Liu, M, Chen, X, Huang, M, Tan, D, Dong, M, Wong, C.C.L, Wang, J, Xu, Y, Wang, H. | | 登録日 | 2016-11-10 | | 公開日 | 2017-01-25 | | 最終更新日 | 2019-11-06 | | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | | 主引用文献 | 4.4 angstrom Resolution Cryo-EM structure of human mTOR Complex 1
Protein Cell, 7, 2016
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1YD0
 | | Crystal structure of the GIY-YIG N-terminal endonuclease domain of UvrC from Thermotoga maritima bound to its catalytic divalent cation: manganese | | 分子名称: | GLYCEROL, MANGANESE (II) ION, UvrABC system protein C | | 著者 | Truglio, J.J, Rhau, B, Croteau, D.L, Wang, L, Skorvaga, M, Karakas, E, DellaVecchia, M.J, Wang, H, Van Houten, B, Kisker, C. | | 登録日 | 2004-12-23 | | 公開日 | 2005-03-01 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Structural insights into the first incision reaction during nucleotide excision repair
Embo J., 24, 2005
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1YD1
 | | Crystal structure of the GIY-YIG N-terminal endonuclease domain of UvrC from Thermotoga maritima bound to its catalytic divalent cation: magnesium | | 分子名称: | GLYCEROL, MAGNESIUM ION, UvrABC system protein C | | 著者 | Truglio, J.J, Rhau, B, Croteau, D.L, Wang, L, Skorvaga, M, Karakas, E, DellaVecchia, M.J, Wang, H, Van Houten, B, Kisker, C. | | 登録日 | 2004-12-23 | | 公開日 | 2005-03-01 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structural insights into the first incision reaction during nucleotide excision repair
Embo J., 24, 2005
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1YD4
 | | Crystal structure of the GIY-YIG N-terminal endonuclease domain of UvrC from Thermotoga maritima: Point mutant Y29F bound to its catalytic divalent cation | | 分子名称: | MANGANESE (II) ION, UvrABC system protein C | | 著者 | Truglio, J.J, Rhau, B, Croteau, D.L, Wang, L, Skorvaga, M, Karakas, E, DellaVecchia, M.J, Wang, H, Van Houten, B, Kisker, C. | | 登録日 | 2004-12-23 | | 公開日 | 2005-03-01 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structural insights into the first incision reaction during nucleotide excision repair
Embo J., 24, 2005
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1YD5
 | | Crystal structure of the GIY-YIG N-terminal endonuclease domain of UvrC from Thermotoga maritima: Point mutant N88A bound to its catalytic divalent cation | | 分子名称: | MANGANESE (II) ION, UvrABC system protein C | | 著者 | Truglio, J.J, Rhau, B, Croteau, D.L, Wang, L, Skorvaga, M, Karakas, E, DellaVecchia, M.J, Wang, H, Van Houten, B, Kisker, C. | | 登録日 | 2004-12-23 | | 公開日 | 2005-03-01 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structural insights into the first incision reaction during nucleotide excision repair
Embo J., 24, 2005
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1YCZ
 | | Crystal structure of the GIY-YIG N-terminal endonuclease domain of UvrC from Thermotoga maritima | | 分子名称: | GLYCEROL, UvrABC system protein C | | 著者 | Truglio, J.J, Rhau, B, Croteau, D.L, Wang, L, Skorvaga, M, Karakas, E, DellaVecchia, M.J, Wang, H, Van Houten, B, Kisker, C. | | 登録日 | 2004-12-23 | | 公開日 | 2005-03-01 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structural insights into the first incision reaction during nucleotide excision repair
Embo J., 24, 2005
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2A4G
 | | Hepatitis C Protease NS3-4A serine protease with Ketoamide Inhibitor SCH225724 Bound | | 分子名称: | ({1-[1-CARBAMOYL-PHENYL-METHYL)-CARBAMOYL]-METHYL}-AMINOOXALYL)-BUTYLCARBAMOYL)-3-METHYL-BUTYLCARBAMOYL)-CYCLOHEXYL-METHYL)-CARBAMIC ACID ISOBUTYL ESTER, NS3 protease/helicase, NS4a peptide, ... | | 著者 | Arasappan, A, Njoroge, F.G, Chan, T.Y, Bennett, F, Bogen, S.L, Chen, K, Gu, H, Hong, L, Jao, E, Liu, Y.T, Lovey, R.G, Parekh, T, Pike, R.E, Pinto, P, Santhanam, B, Venkatraman, S, Vaccaro, H, Wang, H, Yang, X, Zhu, Z, Mckittrick, B, Saksena, A.K, Girijavallabhan, V, Pichardo, J, Butkiewicz, N, Ingram, R, Malcolm, B, Prongay, A.J, Yao, N, Marten, B, Madison, V, Kemp, S, Levy, O, Lim-Wilby, M, Tamura, S, Ganguly, A.K. | | 登録日 | 2005-06-28 | | 公開日 | 2006-07-04 | | 最終更新日 | 2021-10-20 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Hepatitis C virus NS3-4a serine protease inhibitors. SAR of P2' moiety with improved potency.
Bioorg.Med.Chem.Lett., 15, 2005
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1OYN
 | | Crystal structure of PDE4D2 in complex with (R,S)-rolipram | | 分子名称: | ROLIPRAM, ZINC ION, cAMP-specific phosphodiesterase PDE4D2 | | 著者 | Huai, Q, Wang, H, Sun, Y, Kim, H.Y, Liu, Y, Ke, H. | | 登録日 | 2003-04-05 | | 公開日 | 2003-07-15 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Three-dimensional structures of PDE4D in complex with roliprams and implication on inhibitor selectivity
Structure, 11, 2003
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1Q9M
 | | Three dimensional structures of PDE4D in complex with roliprams and implication on inhibitor selectivity | | 分子名称: | ROLIPRAM, ZINC ION, cAMP-specific phosphodiesterase PDE4D2 | | 著者 | Huai, Q, Wang, H, Sun, Y, Kim, H.Y, Liu, Y, Ke, H. | | 登録日 | 2003-08-25 | | 公開日 | 2003-09-02 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Three dimensional structures of PDE4D in complex with roliprams and implication on inhibitor selectivity
Structure, 11, 2003
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8HRI
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8HRJ
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8HRM
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6QIM
 | | Structure of AtPIP2;4 | | 分子名称: | Probable aquaporin PIP2-4 | | 著者 | Schoebel, S, Wang, H. | | 登録日 | 2019-01-21 | | 公開日 | 2019-11-20 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (3.7 Å) | | 主引用文献 | Characterization of aquaporin-driven hydrogen peroxide transport.
Biochim Biophys Acta Biomembr, 1862, 2020
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5ZND
 | | 8-mer nanotube derived from 24-mer rHuHF nanocage | | 分子名称: | Ferritin heavy chain | | 著者 | Wang, W.M, Wang, L.L, Zang, J.C, Chen, H, Zhao, G.H, Wang, H.F. | | 登録日 | 2018-04-09 | | 公開日 | 2018-11-07 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Selective Elimination of the Key Subunit Interfaces Facilitates Conversion of Native 24-mer Protein Nanocage into 8-mer Nanorings.
J. Am. Chem. Soc., 140, 2018
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1Q2U
 | | Crystal structure of DJ-1/RS and implication on familial Parkinson's disease | | 分子名称: | RNA-binding protein regulatory subunit | | 著者 | Huai, Q, Sun, Y, Wang, H, Chin, L.S, Li, L, Robinson, H, Ke, H. | | 登録日 | 2003-07-26 | | 公開日 | 2003-10-07 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Crystal structure of DJ-1/RS and implication on familial Parkinson's disease
Febs Lett., 549, 2003
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8H2H
 | | Cryo-EM structure of a Group II Intron Complexed with its Reverse Transcriptase | | 分子名称: | Group II intron-encoded protein LtrA, LtrB, RNA (5'-R(P*CP*AP*CP*AP*UP*CP*CP*AP*UP*AP*AP*C)-3') | | 著者 | Liu, N, Dong, X.L, Qu, G.S, Wang, J, Wang, H.W, Belfort, M. | | 登録日 | 2022-10-06 | | 公開日 | 2022-11-23 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Functionalized graphene grids with various charges for single-particle cryo-EM.
Nat Commun, 13, 2022
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5GTX
 | | Crystal structure of mutated buckwheat glutaredoxin | | 分子名称: | buckwheat glutaredoxin | | 著者 | Zhang, X, Wang, W, Zhao, Y, Wang, Z, Wang, H. | | 登録日 | 2016-08-23 | | 公開日 | 2017-07-05 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.28 Å) | | 主引用文献 | Structural insights into the binding of buckwheat glutaredoxin with GSH and regulation of its catalytic activity
J. Inorg. Biochem., 173, 2017
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7SBF
 | | PZM21 bound Mu Opioid Receptor-Gi Protein Complex | | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... | | 著者 | Huang, W, Qu, Q, Wang, H, Skiniotis, G, Kobilka, B. | | 登録日 | 2021-09-24 | | 公開日 | 2022-04-20 | | 最終更新日 | 2022-07-06 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | Structure-Based Evolution of G Protein-Biased mu-Opioid Receptor Agonists.
Angew.Chem.Int.Ed.Engl., 61, 2022
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1Y4U
 | | Conformation rearrangement of heat shock protein 90 upon ADP binding | | 分子名称: | Chaperone protein htpG | | 著者 | Huai, Q, Wang, H, Liu, Y, Kim, H, Toft, D, Ke, H. | | 登録日 | 2004-12-01 | | 公開日 | 2005-04-19 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Structures of the N-terminal and middle domains of E. coli Hsp90 and conformation changes upon ADP binding.
Structure, 13, 2005
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1Y4S
 | | Conformation rearrangement of heat shock protein 90 upon ADP binding | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Chaperone protein htpG, MAGNESIUM ION | | 著者 | Huai, Q, Wang, H, Liu, Y, Kim, H, Toft, D, Ke, H. | | 登録日 | 2004-12-01 | | 公開日 | 2005-04-19 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Structures of the N-terminal and middle domains of E. coli Hsp90 and conformation changes upon ADP binding.
Structure, 13, 2005
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