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PDB: 162 件
2FA5
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The crystal structure of an unliganded multiple antibiotic-resistance repressor (MarR) from Xanthomonas campestris
分子名称: CHLORIDE ION, transcriptional regulator marR/emrR family
著者Chin, K.H, Tu, Z.L, Li, J.N, Chou, C.C, Wang, A.H.J, Chou, S.H.
登録日2005-12-06
公開日2006-11-14
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The crystal structure of XC1739: a putative multiple antibiotic-resistance repressor (MarR) from Xanthomonas campestris at 1.8 A resolution
Proteins, 65, 2006
2E9A
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BU of 2e9a by Molmil
E. coli undecaprenyl pyrophosphate synthase in complex with BPH-628
分子名称: (1-HYDROXY-1-PHOSPHONO-2-[1,1';4',1'']TERPHENYL-3-YL-ETHYL)-PHOSPHONIC ACID, Undecaprenyl pyrophosphate synthetase
著者Guo, R.T, Ko, T.P, Cao, R, Liang, P.H, Oldfield, E, Wang, A.H.J.
登録日2007-01-24
公開日2007-06-12
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Bisphosphonates target multiple sites in both cis- and trans-prenyltransferases
Proc.Natl.Acad.Sci.Usa, 104, 2007
4QUM
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BU of 4qum by Molmil
Crystal structure of PTPN3 (PTPH1) in complex with a dually phosphorylated MAPK12 peptide
分子名称: Mitogen-activated protein kinase 12, Tyrosine-protein phosphatase non-receptor type 3
著者Chen, K.E, Meng, T.C, Wang, A.H.J.
登録日2014-07-10
公開日2014-12-10
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (2.516 Å)
主引用文献Reciprocal allosteric regulation of p38 gamma and PTPN3 involves a PDZ domain-modulated complex formation.
Sci.Signal., 7, 2014
4QUN
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BU of 4qun by Molmil
Crystal structure of the PTPN3 (PTPH1) catalytic domain C842S mutant
分子名称: GLYCEROL, PHOSPHATE ION, Tyrosine-protein phosphatase non-receptor type 3
著者Chen, K.E, Meng, T.C, Wang, A.H.J.
登録日2014-07-11
公開日2014-12-10
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献Reciprocal allosteric regulation of p38 gamma and PTPN3 involves a PDZ domain-modulated complex formation.
Sci.Signal., 7, 2014
4QNN
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BU of 4qnn by Molmil
Crystal Structure of phospholipase A 1 from hornet(Vespa basalis) venom
分子名称: CHLORIDE ION, MERCURY (II) ION, Phospholipase A 1 from hornet(Vespa basalis) venom
著者Chuang, C.Y, Ko, T.P, Wang, A.H.J, Hou, M.H.
登録日2014-06-18
公開日2015-06-24
最終更新日2018-03-07
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal Structure of phospholipase A 1 from hornet(Vespa basalis) venom
To be Published
5AYR
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BU of 5ayr by Molmil
The crystal structure of SAUGI/human UDG complex
分子名称: MAGNESIUM ION, Uncharacterized protein, Uracil-DNA glycosylase
著者Wang, H.C, Ko, T.P, Huang, M.F, Wang, A.H.J.
登録日2015-09-02
公開日2016-06-08
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Using structural-based protein engineering to modulate the differential inhibition effects of SAUGI on human and HSV uracil DNA glycosylase.
Nucleic Acids Res., 44, 2016
5AYS
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BU of 5ays by Molmil
Crystal structure of SAUGI/HSV UDG complex
分子名称: Uncharacterized protein, Uracil-DNA glycosylase
著者Wang, H.C, Ko, T.P, Huang, M.F, Wang, A.H.J.
登録日2015-09-02
公開日2016-06-08
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.09 Å)
主引用文献Using structural-based protein engineering to modulate the differential inhibition effects of SAUGI on human and HSV uracil DNA glycosylase.
Nucleic Acids Res., 44, 2016
3EU0
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BU of 3eu0 by Molmil
Crystal structure of the S-nitrosylated Cys215 of PTP1B
分子名称: Tyrosine-protein phosphatase non-receptor type 1
著者Chu, H.M, Wang, A.H.J, Chen, Y.Y, Pan, K.T, Wang, D.L, Khoo, K.H, Meng, T.C.
登録日2008-10-09
公開日2008-11-11
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Cysteine S-Nitrosylation Protects Protein-tyrosine Phosphatase 1B against Oxidation-induced Permanent Inactivation
J.Biol.Chem., 283, 2008
3ACW
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BU of 3acw by Molmil
Crystal structure of the C(30) carotenoid dehydrosqualene synthase from Staphylococcus aureus complexed with BPH-651
分子名称: (3R)-3-biphenyl-4-yl-1-azabicyclo[2.2.2]octan-3-ol, Dehydrosqualene synthase
著者Liu, C.I, Jeng, W.Y, Wang, A.H.J, Oldfield, E.
登録日2010-01-13
公開日2010-11-24
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.63 Å)
主引用文献Mechanism of action and inhibition of dehydrosqualene synthase
Proc.Natl.Acad.Sci.USA, 107, 2010
3P19
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BU of 3p19 by Molmil
Improved NADPH-dependent Blue Fluorescent Protein
分子名称: NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Putative blue fluorescent protein
著者Kao, T.H, Chen, Y, Pai, C.H, Wang, A.H.J.
登録日2010-09-30
公開日2011-07-20
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Structure of a NADPH-dependent blue fluorescent protein revealed the unique role of Gly176 on the fluorescence enhancement.
J.Struct.Biol., 174, 2011
3PB4
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BU of 3pb4 by Molmil
Crystal structure of the catalytic domain of human Golgi-resident glutaminyl cyclase at pH 6.0
分子名称: Glutaminyl-peptide cyclotransferase-like protein, ZINC ION
著者Huang, K.F, Liaw, S.S, Huang, W.L, Chia, C.Y, Lo, Y.C, Chen, Y.L, Wang, A.H.J.
登録日2010-10-20
公開日2011-02-02
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.13 Å)
主引用文献Structures of human Golgi-resident glutaminyl cyclase and its complexes with inhibitors reveal a large loop movement upon inhibitor binding
J.Biol.Chem., 286, 2011
3PB6
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BU of 3pb6 by Molmil
Crystal structure of the catalytic domain of human Golgi-resident glutaminyl cyclase at pH 6.5
分子名称: CACODYLATE ION, Glutaminyl-peptide cyclotransferase-like protein, ZINC ION
著者Huang, K.F, Liaw, S.S, Huang, W.L, Chia, C.Y, Lo, Y.C, Chen, Y.L, Wang, A.H.J.
登録日2010-10-20
公開日2011-02-02
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.05 Å)
主引用文献Structures of human Golgi-resident glutaminyl cyclase and its complexes with inhibitors reveal a large loop movement upon inhibitor binding
J.Biol.Chem., 286, 2011
3PBB
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BU of 3pbb by Molmil
Crystal structure of human secretory glutaminyl cyclase in complex with PBD150
分子名称: 1-(3,4-dimethoxyphenyl)-3-[3-(1H-imidazol-1-yl)propyl]thiourea, Glutaminyl-peptide cyclotransferase, ZINC ION
著者Huang, K.F, Liaw, S.S, Huang, W.L, Chia, C.Y, Lo, Y.C, Chen, Y.L, Wang, A.H.J.
登録日2010-10-20
公開日2011-02-02
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structures of human Golgi-resident glutaminyl cyclase and its complexes with inhibitors reveal a large loop movement upon inhibitor binding
J.Biol.Chem., 286, 2011
3PB8
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Crystal structure of the catalytic domain of human Golgi-resident glutaminyl cyclase in complex with N-acetylhistamine
分子名称: Glutaminyl-peptide cyclotransferase-like protein, N-[2-(1H-IMIDAZOL-4-YL)ETHYL]ACETAMIDE, ZINC ION
著者Huang, K.F, Liaw, S.S, Huang, W.L, Chia, C.Y, Lo, Y.C, Chen, Y.L, Wang, A.H.J.
登録日2010-10-20
公開日2011-02-02
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.13 Å)
主引用文献Structures of human Golgi-resident glutaminyl cyclase and its complexes with inhibitors reveal a large loop movement upon inhibitor binding
J.Biol.Chem., 286, 2011
3ACX
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BU of 3acx by Molmil
Crystal structure of the C(30) carotenoid dehydrosqualene synthase from Staphylococcus aureus complexed with BPH-673
分子名称: Dehydrosqualene synthase, N-(1-methylethyl)-3-[(3-prop-2-en-1-ylbiphenyl-4-yl)oxy]propan-1-amine
著者Liu, C.I, Jeng, W.Y, Wang, A.H.J, Oldfield, E.
登録日2010-01-13
公開日2010-11-24
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.31 Å)
主引用文献Mechanism of action and inhibition of dehydrosqualene synthase
Proc.Natl.Acad.Sci.USA, 107, 2010
3ACY
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BU of 3acy by Molmil
Crystal structure of the C(30) carotenoid dehydrosqualene synthase from Staphylococcus aureus complexed with BPH-702
分子名称: (1R)-4-[3-(2-benzylphenoxy)phenyl]-1-phosphonobutane-1-sulfonic acid, Dehydrosqualene synthase, MAGNESIUM ION
著者Liu, C.I, Jeng, W.Y, Wang, A.H.J, Oldfield, E.
登録日2010-01-13
公開日2010-11-24
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.84 Å)
主引用文献Mechanism of action and inhibition of dehydrosqualene synthase
Proc.Natl.Acad.Sci.USA, 107, 2010
3PB7
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BU of 3pb7 by Molmil
Crystal structure of the catalytic domain of human Golgi-resident glutaminyl cyclase in complex with PBD150
分子名称: 1-(3,4-dimethoxyphenyl)-3-[3-(1H-imidazol-1-yl)propyl]thiourea, Glutaminyl-peptide cyclotransferase-like protein, ZINC ION
著者Huang, K.F, Liaw, S.S, Huang, W.L, Chia, C.Y, Lo, Y.C, Chen, Y.L, Wang, A.H.J.
登録日2010-10-20
公開日2011-02-02
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Structures of human Golgi-resident glutaminyl cyclase and its complexes with inhibitors reveal a large loop movement upon inhibitor binding
J.Biol.Chem., 286, 2011
3PB9
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BU of 3pb9 by Molmil
Crystal structure of the catalytic domain of human Golgi-resident glutaminyl cyclase in complex with 1-benzylimidazole
分子名称: 1-BENZYL-1H-IMIDAZOLE, Glutaminyl-peptide cyclotransferase-like protein, ZINC ION
著者Huang, K.F, Liaw, S.S, Huang, W.L, Chia, C.Y, Lo, Y.C, Chen, Y.L, Wang, A.H.J.
登録日2010-10-20
公開日2011-02-02
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.12 Å)
主引用文献Structures of human Golgi-resident glutaminyl cyclase and its complexes with inhibitors reveal a large loop movement upon inhibitor binding
J.Biol.Chem., 286, 2011
3IWZ
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BU of 3iwz by Molmil
The c-di-GMP Responsive Global Regulator CLP Links Cell-Cell Signaling to Virulence Gene Expression in Xanthomonas campestris
分子名称: Catabolite activation-like protein
著者Chin, K.H, Tu, Z.L, Tseng, Y.H, Dow, J.M, Wang, A.H.J, Chou, S.H.
登録日2009-09-03
公開日2009-12-15
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The cAMP receptor-like protein CLP is a novel c-di-GMP receptor linking cell-cell signaling to virulence gene expression in Xanthomonas campestris.
J.Mol.Biol., 396, 2010
2ZUD
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BU of 2zud by Molmil
Crystal Structure of Left-handed RadA Filament
分子名称: DNA repair and recombination protein radA
著者Chang, Y.W, Ko, T.P, Wang, T.F, Wang, A.H.J.
登録日2008-10-16
公開日2009-04-07
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Three new structures of left-handed RADA helical filaments: structural flexibility of N-terminal domain is critical for recombinase activity
Plos One, 4, 2009
2ZUC
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Crystal structure of left-handed RadA filament
分子名称: DNA repair and recombination protein radA
著者Chang, Y.W, Ko, T.P, Wang, T.F, Wang, A.H.J.
登録日2008-10-15
公開日2009-04-07
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Three new structures of left-handed RADA helical filaments: structural flexibility of N-terminal domain is critical for recombinase activity
Plos One, 4, 2009
2ZUB
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Left handed RadA
分子名称: DNA repair and recombination protein radA
著者Chang, Y.W, Ko, T.P, Wang, T.F, Wang, A.H.J.
登録日2008-10-15
公開日2009-04-07
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Three new structures of left-handed RADA helical filaments: structural flexibility of N-terminal domain is critical for recombinase activity
Plos One, 4, 2009
2Z43
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Structure of a twinned crystal of RadA
分子名称: DNA repair and recombination protein radA
著者Chen, L.T, Ko, T.P, Wang, A.H.J, Wang, T.F.
登録日2007-06-12
公開日2007-11-13
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献Structural and functional analyses of five conserved positively charged residues in the L1 and N-terminal DNA binding motifs of archaeal RADA protein
Plos One, 2, 2007
2I6O
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Crystal structure of the complex of the archaeal sulfolobus PTP-fold phosphatase with phosphopeptides N-G-(p)Y-K-N
分子名称: CALCIUM ION, IMIDAZOLE, NK(PTR)GN, ...
著者Chu, H.M, Wang, A.H.J.
登録日2006-08-29
公開日2007-03-13
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Enzyme-substrate interactions revealed by the crystal structures of the archaeal Sulfolobus PTP-fold phosphatase and its phosphopeptide complexes
Proteins, 66, 2006
2I6J
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Crystal structure of the complex of the archaeal sulfolobus PTP-fold phosphatase with phosphate ion
分子名称: PHOSPHATE ION, Sulfolobus solfataricus protein tyrosine phosphatase
著者Chu, H.M, Wang, A.H.J.
登録日2006-08-29
公開日2007-03-13
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.66 Å)
主引用文献Enzyme-substrate interactions revealed by the crystal structures of the archaeal Sulfolobus PTP-fold phosphatase and its phosphopeptide complexes
Proteins, 66, 2006

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