4QUN
Crystal structure of the PTPN3 (PTPH1) catalytic domain C842S mutant
Summary for 4QUN
Entry DOI | 10.2210/pdb4qun/pdb |
Related | 2B49 4QUM |
Descriptor | Tyrosine-protein phosphatase non-receptor type 3, PHOSPHATE ION, GLYCEROL, ... (4 entities in total) |
Functional Keywords | alpha beta, hydrolase |
Biological source | Homo sapiens (human) |
Cellular location | Cell membrane; Peripheral membrane protein; Cytoplasmic side: P26045 |
Total number of polymer chains | 2 |
Total formula weight | 70145.38 |
Authors | Chen, K.E.,Meng, T.C.,Wang, A.H.J. (deposition date: 2014-07-11, release date: 2014-12-10, Last modification date: 2023-11-08) |
Primary citation | Chen, K.E.,Lin, S.Y.,Wu, M.J.,Ho, M.R.,Santhanam, A.,Chou, C.C.,Meng, T.C.,Wang, A.H.J. Reciprocal allosteric regulation of p38 gamma and PTPN3 involves a PDZ domain-modulated complex formation. Sci.Signal., 7:ra98-ra98, 2014 Cited by PubMed: 25314968DOI: 10.1126/scisignal.2005722 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.86 Å) |
Structure validation
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